Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation

Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts

(2016) Adam Byron et al.   CURRENT OPINION IN CELL BIOLOGY

Expression ofN-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels

(2016) Jishun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells

(2016) Sicong Hou et al.   Scientific Reports

Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation viaN-Glycosylation

(2015) Qinglei Hang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialic Acids Sweeten a Tumor's Life

(2014) C. Bull et al.   CANCER RESEARCH

An Oncogenic Protein Golgi Phosphoprotein 3 Up-regulates Cell Migration via Sialylation

(2014) Tomoya Isaji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic Domain Interactions of Syndecan-1 and Syndecan-4 with α6β4 Integrin Mediate Human Epidermal Growth Factor Receptor (HER1 and HER2)-dependent Motility and Survival

(2014) Haiyao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

(2014) Matthew J. Paszek et al.   NATURE

Dynamic catch of a Thy-1–α5β1+syndecan-4 trimolecular complex

(2014) Vincent F. Fiore et al.   Nature Communications

Expression of integrins α3β1 and α5β1 and GlcNAc β1,6 glycan branching influences metastatic melanoma cell migration on fibronectin

(2013) Ewa Pocheć et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Roles of Talin and Kindlin in Regulating Integrin α5β1 Function and Trafficking

(2012) Coert Margadant et al.   CURRENT BIOLOGY

Epidermal Growth Factor (EGF) Regulates α5β1 Integrin Activation State in Human Cancer Cell Lines through the p90RSK-dependent Phosphorylation of Filamin A

(2012) Daniel Vial et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

(2012) Masamichi Nagae et al.   JOURNAL OF CELL BIOLOGY

Regulation of Integrin Activation

(2011) Chungho Kim et al.   Annual Review of Cell and Developmental Biology

Mechanisms of integrin activation and trafficking

(2011) Coert Margadant et al.   CURRENT OPINION IN CELL BIOLOGY

Integrin Structure, Activation, and Interactions

(2011) I. D. Campbell et al.   Cold Spring Harbor Perspectives in Biology

Role of Altered Sialylation of the I-Like Domain of β1 Integrin in the Binding of Fibronectin to β1 Integrin: Thermodynamics and Conformational Analyses

(2010) Di Pan et al.   BIOPHYSICAL JOURNAL

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signal co-operation between integrins and other receptor systems

(2009) Charles H. Streuli et al.   BIOCHEMICAL JOURNAL

Importance of N-Glycosylation on α5β1 Integrin for Its Biological Functions

(2009) Jianguo Gu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

AnN-Glycosylation Site on theβ-Propeller Domain of the Integrin α5 Subunit Plays Key Roles in Both Its Function and Site-specific Modification byβ1,4-N-Acetylglucosaminyltransferase III

(2009) Yuya Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Glycosylation of the I-like Domain of β1 Integrin Is Essential for β1 Integrin Expression and Biological Function

(2009) Tomoya Isaji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bisecting GlcNAc Residues on Laminin-332 Down-regulate Galectin-3-dependent Keratinocyte Motility

(2009) Yoshinobu Kariya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialylation of β1 Integrins Blocks Cell Adhesion to Galectin-3 and Protects Cells against Galectin-3-induced Apoptosis

(2008) Ya Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function

(2008) Daniel R Christie et al.   Journal of Ovarian Research