S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure

Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effectsin vivoin a mouse model of hypertrophic cardiomyopathy

(2015) Frederik Flenner et al.   CARDIOVASCULAR RESEARCH

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

(2015) Lucie Carrier et al.   GENE

The Year in Cardiology 2013: heart failure

(2014) G. Ertl et al.   EUROPEAN HEART JOURNAL

Novel aspects of ROS signalling in heart failure

(2013) Anne D. Hafstad et al.   BASIC RESEARCH IN CARDIOLOGY

GSK3β Phosphorylates Newly Identified Site in the Proline-Alanine–Rich Region of Cardiac Myosin–Binding Protein C and Alters Cross-Bridge Cycling Kinetics in Human

(2013) Diederik W. D. Kuster et al.   CIRCULATION RESEARCH

Oxidative Stress and Sarcomeric Proteins

(2013) Susan F. Steinberg   CIRCULATION RESEARCH

Emerging mechanisms of glutathione-dependent chemistry in biology and disease

(2013) Yvonne M. W. Janssen-Heininger et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The PEG-switch assay: A fast semi-quantitative method to determine protein reversible cysteine oxidation

(2013) Joseph Robert Burgoyne et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein C

(2013) Bindiya G. Patel et al.   Frontiers in Physiology

Ranolazine Improves Cardiac Diastolic Dysfunction Through Modulation of Myofilament Calcium Sensitivity

(2012) Joshua D. Lovelock et al.   CIRCULATION RESEARCH

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

(2012) Mark Pfuhl et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

(2012) Susanne A.I. Seidel et al.   METHODS

Phosphatase-1 inhibitor-1 in physiological and pathological  -adrenoceptor signalling

(2011) K. Wittkopper et al.   CARDIOVASCULAR RESEARCH

A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function

(2011) Sakthivel Sadayappan et al.   CIRCULATION RESEARCH

Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function

(2011) Sabine J. van Dijk et al.   Circulation-Heart Failure

cMyBP-C as a promiscuous substrate: phosphorylation by non-PKA kinases and its potential significance

(2011) Sonya C. Bardswell et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Cardiac myosin binding protein C phosphorylation in cardiac disease

(2011) Diederik W. D. Kuster et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Novel Role for p90 Ribosomal S6 Kinase in the Regulation of Cardiac Myofilament Phosphorylation

(2010) Friederike Cuello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of cardiac myosin binding protein-C phosphorylation in human heart muscle

(2010) O'Neal Copeland et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease

(2010) Nazha Hamdani et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

Cardiac Myosin Binding Protein-C Phosphorylation in a β-Myosin Heavy Chain Background

(2009) Sakthivel Sadayappan et al.   CIRCULATION

Nitroxyl Activates SERCA in Cardiac Myocytes via Glutathiolation of Cysteine 674

(2009) Steve Lancel et al.   CIRCULATION RESEARCH

Reactive oxidative metabolites are associated with atrial conduction disturbance in patients with atrial fibrillation

(2009) Masayuki Shimano et al.   HEART RHYTHM

Distinct Sarcomeric Substrates Are Responsible for Protein Kinase D-mediated Regulation of Cardiac Myofilament Ca2+Sensitivity and Cross-bridge Cycling

(2009) Sonya C. Bardswell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation and function of cardiac myosin binding protein-C in health and disease

(2009) David Barefield et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac Myosin-Binding Protein C Modulates the Tuning of the Molecular Motor in the Heart

(2008) Yves Lecarpentier et al.   BIOPHYSICAL JOURNAL

Acceleration of Crossbridge Kinetics by Protein Kinase A Phosphorylation of Cardiac Myosin Binding Protein C Modulates Cardiac Function

(2008) Carl W. Tong et al.   CIRCULATION RESEARCH

Multiplex Kinase Signaling Modifies Cardiac Function at the Level of Sarcomeric Proteins

(2008) R. John Solaro   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle

(2008) Adam M. Jacques et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY