Endothelial FoxO proteins impair insulin sensitivity and restrain muscle angiogenesis in response to a high-fat diet

MicroRNA-181b Improves Glucose Homeostasis and Insulin Sensitivity by Regulating Endothelial Function in White Adipose TissueNovelty and Significance

(2016) Xinghui Sun et al.   CIRCULATION RESEARCH

FOXO1 couples metabolic activity and growth state in the vascular endothelium

(2016) Kerstin Wilhelm et al.   NATURE

Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis

(2015) Nicolas J. Pillon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Forkhead Box O-1 Modulation Improves Endothelial Insulin Resistance in Human Obesity

(2015) S. Karki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased Skeletal Muscle Capillarization Independently Enhances Insulin Sensitivity in Older Adults After Exercise Training and Detraining

(2015) Steven J. Prior et al.   DIABETES

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Forkhead BoxO transcription factors restrain exercise-induced angiogenesis

(2014) Dara Slopack et al.   JOURNAL OF PHYSIOLOGY-LONDON

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

Endothelial FoxO1 is an intrinsic regulator of thrombospondin 1 expression that restrains angiogenesis in ischemic muscle

(2013) Emilie Roudier et al.   ANGIOGENESIS

Capillary Endothelial Fatty Acid Binding Proteins 4 and 5 Play a Critical Role in Fatty Acid Uptake in Heart and Skeletal Muscle

(2013) Tatsuya Iso et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance

(2013) Annayya R. Aroor et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

High-fat feeding induces angiogenesis in skeletal muscle and activates angiogenic pathways in capillaries

(2012) Mika Silvennoinen et al.   ANGIOGENESIS

FoxOs Integrate Pleiotropic Actions of Insulin in Vascular Endothelium to Protect Mice from Atherosclerosis

(2012) Kyoichiro Tsuchiya et al.   Cell Metabolism

Identification of a Mechanism Underlying Regulation of the Anti-Angiogenic Forkhead Transcription Factor FoxO1 in Cultured Endothelial Cells and Ischemic Muscle

(2011) Malgorzata Milkiewicz et al.   AMERICAN JOURNAL OF PATHOLOGY

Prevention of Overweight/Obesity as a Strategy to Optimize Cardiovascular Health

(2011) Marc-Andre Cornier et al.   CIRCULATION

Tumor Necrosis Factor α and Regulation of Adipose Tissue

(2010) Erik Arner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrative analysis of RUNX1 downstream pathways and target genes

(2009) Joëlle Michaud et al.   BMC GENOMICS

Foxo1 Links Hyperglycemia to LDL Oxidation and Endothelial Nitric Oxide Synthase Dysfunction in Vascular Endothelial Cells

(2009) J. Tanaka et al.   DIABETES

Direct and macrophage-mediated actions of fatty acids causing insulin resistance in muscle cells

(2009) Phillip J. Bilan et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY