Single-cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis

GPR56-Related Polymicrogyria

(2015) Neelu A. Desai et al.   JOURNAL OF CHILD NEUROLOGY

Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3-Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects

(2015) Yasuhiro Wada et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive molecular characterization of human adipocytes reveals a transient brown phenotype

(2015) Andrea Guennoun et al.   Journal of Translational Medicine

Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice

(2014) Liping Qiao et al.   DIABETOLOGIA

Lipocalin 2 Regulates Brown Fat Activation via a Nonadrenergic Activation Mechanism

(2014) Yuanyuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

18F-FDG PET/CT Monitoring of  3 Agonist-Stimulated Brown Adipocyte Recruitment in White Adipose Tissue

(2014) J. W. Park et al.   JOURNAL OF NUCLEAR MEDICINE

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

(2014) J. P. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNAs regulate adipogenesis

(2013) Lei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant

(2012) S. C. Gunawardana et al.   DIABETES

Long-Acting FGF21 Has Enhanced Efficacy in Diet-Induced Obese Mice and in Obese Rhesus Monkeys

(2012) Murielle M. Véniant et al.   ENDOCRINOLOGY

Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans

(2012) T Yoneshiro et al.   INTERNATIONAL JOURNAL OF OBESITY

The role of adipokines in β-cell failure of type 2 diabetes

(2012) Simon J Dunmore et al.   JOURNAL OF ENDOCRINOLOGY

Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin

(2012) Jeffrey S. Dubins et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

FGF21 Takes a Fat Bite

(2012) C. Canto et al.   SCIENCE

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling

(2012) Jeremie Boucher et al.   Nature Communications

Molecules affecting hypothalamic control of core body temperature in response to calorie intake

(2012) Tamas Bartfai et al.   Frontiers in Genetics

β1-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor-knockout mice via nonshivering thermogenesis

(2011) Charlotte L. Mattsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brown fat and obesity: the next big thing?

(2011) Mark Stephens et al.   CLINICAL ENDOCRINOLOGY

Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors

(2011) Manuel Sanchez-Alavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse

(2011) J. T. Eppig et al.   NUCLEIC ACIDS RESEARCH

Drug targets: single-cell transcriptomics hastens unbiased discovery

(2011) Tamas Bartfai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men

(2010) C. Benedict et al.   DIABETES

Brown fat thermogenesis and body weight regulation in mice: relevance to humans

(2010) L P Kozak et al.   INTERNATIONAL JOURNAL OF OBESITY

Thyroid hormones: igniting brown fat via the brain

(2010) Barbara Cannon et al.   NATURE MEDICINE

The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics

(2010) J. A. Blake et al.   NUCLEIC ACIDS RESEARCH

Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response

(2010) James Eberwine et al.   PHARMACOLOGY & THERAPEUTICS

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Recruitment of brown fat and conversion of white into brown adipocytes: Strategies to fight the metabolic complications of obesity?

(2009) Dominique Langin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Insulin Causes Hyperthermia by Direct Inhibition of Warm-Sensitive Neurons

(2009) M. Sanchez-Alavez et al.   DIABETES

The β3-Adrenoceptor Agonist GW427353 (Solabegron) Decreases Excitability of Human Enteric Neurons via Release of Somatostatin

(2009) Michael Schemann et al.   GASTROENTEROLOGY

Transcriptional control of brown adipocyte development and physiological function--of mice and men

(2009) P. Seale et al.   GENES & DEVELOPMENT

Sensory and sympathetic nervous system control of white adipose tissue lipolysis

(2009) Timothy J. Bartness et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination

(2008) S. Li et al.   JOURNAL OF NEUROSCIENCE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE