PM2.5 aggravates NQO1-induced mucus hyper-secretion through release of neutrophil extracellular traps in an asthma model

Investigation of the chemical components of ambient fine particulate matter (PM2.5) associated with in vitro cellular responses to oxidative stress and inflammation

(2020) Fanfan Xu et al.   ENVIRONMENT INTERNATIONAL

Diesel particulate matter2.5 promotes epithelial-mesenchymal transition of human retinal pigment epithelial cells via generation of reactive oxygen species

(2020) Hyesook Lee et al.   ENVIRONMENTAL POLLUTION

Air pollution and the development of asthma from birth until young adulthood

(2020) Ulrike Gehring et al.   EUROPEAN RESPIRATORY JOURNAL

Oxidative stress activates the TRPM2-Ca2+-NLRP3 axis to promote PM2.5-induced lung injury of mice

(2020) Chunyuan Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation

(2020) David Siegel et al.   Redox Biology

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

(2019) Marrah E Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The receptor for advanced glycation end products is a critical mediator of type 2 cytokine signaling in the lungs

(2019) Timothy N. Perkins et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis

(2018) Kentaro Takahashi et al.   EUROPEAN RESPIRATORY JOURNAL

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

(2018) Nick Shrine et al.   Lancet Respiratory Medicine

Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation

(2017) Marie Toussaint et al.   NATURE MEDICINE

Airway Mucus and Asthma: The Role of MUC5AC and MUC5B

(2017) Luke Bonser et al.   Journal of Clinical Medicine

Urban PM2.5 exacerbates allergic inflammation in the murine lung via a TLR2/TLR4/MyD88-signaling pathway

(2017) Miao He et al.   Scientific Reports

Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012

(2016) Kiros Berhane et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB

(2015) T. Xie et al.   CLINICAL AND EXPERIMENTAL ALLERGY

TNFα and IL-6 Responses to Particulate Matter in Vitro: Variation According to PM Size, Season, and Polycyclic Aromatic Hydrocarbon and Soil Content

(2015) Natalia Manzano-León et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A Mutually Inhibitory Feedback Loop between the 20S Proteasome and Its Regulator, NQO1

(2015) Oren Moscovitz et al.   MOLECULAR CELL

Outdoor air pollution and asthma

(2014) Michael Guarnieri et al.   LANCET

Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles

(2014) Susanne Walz et al.   NATURE

Unlocking the quiet zone: the small airway asthma phenotype

(2014) Brian Lipworth et al.   Lancet Respiratory Medicine

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

(2013) Wendy C. Moore et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia

(2012) Marisa L. Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Size, source and chemical composition as determinants of toxicity attributable to ambient particulate matter

(2012) Frank J. Kelly et al.   ATMOSPHERIC ENVIRONMENT

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Black Carbon as an Additional Indicator of the Adverse Health Effects of Airborne Particles Compared with PM 10 and PM 2.5

(2011) Nicole A.H. Janssen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Important role of neutrophils in the late asthmatic response in mice

(2011) Takeshi Nabe et al.   LIFE SCIENCES

Hospital Admissions and Chemical Composition of Fine Particle Air Pollution

(2009) Michelle L. Bell et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

NAD(P)H: Quinone oxidoreductase 1, glutathione S-transferase M1, environmental tobacco smoke exposure, and childhood asthma

(2009) Yu-Fen Li et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS