PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice

IL-32 exacerbates adenoid hypertrophy via activating NLRP3-mediated cell pyroptosis, which promotes inflammation

(2021) Junmei Zhang et al.   Molecular Medicine Reports

Fine particulate matter-induced lung inflammation is mediated by pyroptosis in mice

(2021) Juan Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Tanshinone IIA alleviates blast-induced inflammation, oxidative stress and apoptosis in mice partly by inhibiting the PI3K/Akt/FoxO1 signaling pathway

(2020) Yunen Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

M1 macrophage features in severe Plasmodium falciparum malaria patients with pulmonary oedema

(2020) Aekkarin Klinkhamhom et al.   MALARIA JOURNAL

Long-term effect of personal PM2.5 exposure on lung function: A panel study in China

(2020) Yun Zhou et al.   JOURNAL OF HAZARDOUS MATERIALS

Preconditioning with rHMGB1 ameliorates lung ischemia–reperfusion injury by inhibiting alveolar macrophage pyroptosis via the Keap1/Nrf2/HO-1 signaling pathway

(2020) Lin Fei et al.   Journal of Translational Medicine

Quantifying public health benefits of PM2.5 reduction and spatial distribution analysis in China

(2020) Guiwen Luo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The angiotensin-converting enzyme 2/angiotensin (1–7)/mas axis protects against pyroptosis in LPS-induced lung injury by inhibiting NLRP3 activation

(2020) Haihua Huang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Circular RNA circBbs9 promotes PM2.5-induced lung inflammation in mice via NLRP3 inflammasome activation

(2020) Meizhen Li et al.   ENVIRONMENT INTERNATIONAL

Cancer-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to promote lung cancer progression

(2020) Manman Liang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis alleviates excess molybdenum-induced apoptosis in duck renal tubular epithelial cells

(2020) Shaoxing Pi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation

(2020) Ken-ichiro Tanaka et al.   ENVIRONMENTAL POLLUTION

Astragaloside IV alleviates PM2.5-induced lung injury in rats by modulating TLR4/MyD88/NF-κB signalling pathway

(2020) Yongcan Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hydrogen sulfide attenuates lung ischemia–reperfusion injury through SIRT3-dependent regulation of mitochondrial function in type 2 diabetic rats

(2019) Tao Jiang et al.   SURGERY

STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3

(2019) Ning Li et al.   Redox Biology

Resveratrol alleviates chronic “real-world” ambient particulate matter-induced lung inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice

(2019) Shibin Ding et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Targeting NLRP3 Inflammasome Activation in Severe Asthma

(2019) Efthymia Theofani et al.   Journal of Clinical Medicine

Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived PM 2.5

(2017) B. Leclercq et al.   ENVIRONMENTAL POLLUTION

Nickle(II) ions exacerbate bleomycin-induced pulmonary inflammation and fibrosis by activating the ROS/Akt signaling pathway

(2017) Lawei Yang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Anti-inflammatory effects on ischemia/reperfusion-injured lung transplants by the cluster of differentiation 26/dipeptidylpeptidase 4 (CD26/DPP4) inhibitor vildagliptin

(2017) Jae-Hwi Jang et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gasdermins: Effectors of Pyroptosis

(2017) Stephen B. Kovacs et al.   TRENDS IN CELL BIOLOGY

Oxymatrine on Hsp90a expression and apoptosis in a model of lung ischemia-reperfusion injury

(2017) Bing Zhu et al.   Experimental and Therapeutic Medicine

Roles of Caspases in Necrotic Cell Death

(2016) Junying Yuan et al.   CELL

Oxidative Stress and Lung Ischemia-Reperfusion Injury

(2015) Renata Salatti Ferrari et al.   Oxidative Medicine and Cellular Longevity

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Differential inflammatory responses in aging and disease: TNF-α and IL-6 as possible biomarkers

(2010) David de Gonzalo-Calvo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell death in the host response to infection

(2008) K Labbé et al.   CELL DEATH AND DIFFERENTIATION