Review
Pharmacology & Pharmacy
Taylor Bourn, Sister Michaela Serpa
Summary: Bupivacaine/meloxicam extended-release solution is a reliable and safe non-opioid local anesthetic for postoperative pain management for 72 hours, effectively reducing pain and minimizing opioid consumption.
ANNALS OF PHARMACOTHERAPY
(2023)
Article
Medicine, General & Internal
Anna Danielewicz, Marek Fatyga, Grzegorz Starobrat, Monika Rozanska-Boczula, Magdalena Wojciak, Ireneusz Sowa, Slawomir Dresler, Michal Latalski
Summary: The study suggests that pre-closure bupivacaine injection may help alleviate pain in the early postoperative period for children and adolescents undergoing spinal deformity correction. However, the use of local anesthetics does not significantly impact overall opioid consumption in the long term and may lead to increased bleeding.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nursing
Manuel Luque Oliveros, Ruben Morilla Romero de la Osa
Summary: The study evaluated the effectiveness of wound infiltration with 0.5% bupivacaine for pain management in cardiac surgery patients. Results showed a significant difference in pain scores between the bupivacaine and saline infiltration groups, with bupivacaine providing clinically and statistically significant pain relief in the immediate post-operative period.
NURSING IN CRITICAL CARE
(2022)
Article
Anesthesiology
Jinjie Cui, Qing Xu, Zhengya Yu, Jinwen Sun, Yi Zheng, Wei Huang, Yunxian Yu, Shu Gao, Zhenjun Wang, Shanchun Zhang
Summary: The study found that HYR-PB21 has better analgesic efficacy and a similar safety profile compared to bupivacaine HCl for patients after haemorrhoidectomy. This study suggests that HYR-PB21 is an effective option for controlling postoperative pain.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Medicine, General & Internal
Francisco Javier Quesada-Bravo, Ana Rocio Garcia-Carricondo, Fernando Espin-Galvez, Carmen Fernandez-Sanchez, Damaso Fernandez-Gines, Maria del Mar Requena-Mullor, Raquel Alarcon-Rodriguez
Summary: The study compared the benefits of combining dexamethasone-bupivacaine with articaine-epinephrine as an anesthetic block after third molar surgery. Results showed that the combination significantly reduced postoperative pain and decreased analgesic drug consumption, supporting the use of bupivacaine as an alternative to articaine in oral surgery.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Atul Dilawri, Marcia Wyman, Sneha Shah
Summary: A retrospective study in a single medical center found that compared with LB, IRB can reduce total opioid consumption in adult surgical patients within 24 and 72 hours postoperatively, and also shorten postoperative length of stay.
ANNALS OF PHARMACOTHERAPY
(2022)
Review
Clinical Neurology
Sung Huang Laurent Tsai, Yagiz Ugur Yolcu, Shao-Wen Hung, Shyam J. Kurian, Mohammed Ali Alvi, Tsai-Sheng Fu, Mohamad Bydon
Summary: The study aimed to examine the outcomes of intraoperative intravenous lidocaine and intrawound or epidural bupivacaine use in spine surgery for reducing postoperative pain and opioid consumption. The results showed that lidocaine had a stronger effect on reducing opioid consumption compared to bupivacaine, with no significant difference between the two in postoperative VAS score, length of stay, and nausea/vomiting.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Article
Biotechnology & Applied Microbiology
Xiaohong Chen, Jianfeng Zhang, Yan Yu, Haoran Wang, Genshan Ma, Di Wang, Hanzhong Cao, Jianping Yang
Summary: Ultrasound-triggered Lido-PPIX@ER hydrogel offers controlled release of lidocaine for the management of postoperative pain, providing individualized and timed relief.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Orthopedics
Yuwarat Monteerarat, Pimolpan Misen, Panai Laohaprasitiporn, Pattarawat Wongsaengaroonsri, Nittaya Lektrakul, Torpon Vathana
Summary: This study investigated the prevalence of dorsal proximal interphalangeal (PIP) joint tenderness in trigger finger patients and compared postoperative outcomes between patients with and without joint tenderness. The results showed that 46.8% of patients had PIP joint tenderness, which differs from previous perceptions. Patients with joint tenderness experienced more overall postoperative pain for up to 6 weeks and reported residual minor pain for up to 3 months. The only observed risk factor was the patient's occupation.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Anesthesiology
Christina W. Fidkowski, Nandak Choksi, Mohamed-Rida Alsaden
Summary: The study compared the analgesic efficacy of plain bupivacaine, liposomal bupivacaine, and a mixture of both in TAP block for postoperative pain relief in abdominal surgeries. Results showed that the mixture did not provide better analgesia compared to using liposomal bupivacaine or plain bupivacaine alone.
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2021)
Article
Anesthesiology
Michael Suer, Nicholas Philips, Stephanie Kliethermes, Tamara Scerpella, Nalini Sehgal
Summary: This study evaluates predictors of pain following nonarthroplasty shoulder surgery and finds that increased baseline kinesiophobia and pain catastrophizing are associated with greater postoperative pain.
Article
Gastroenterology & Hepatology
Nolberto A. Medina-Gallardo, Xavier De Castro, Enric De Caralt-Mestres, Yuhamy Curbelo-Pena, Andres Dardano-Berriel, Jordi Serrat Puyol, Pere Roura-Poch, Helena Vallverdu-Cartie
Summary: This study evaluated the effectiveness of infiltrating surgical wounds with bupivacaine and triamcinolone in relieving postoperative pain in hemorrhoidectomy. The results showed that infiltration reduced postoperative pain and morphine requirements.
DISEASES OF THE COLON & RECTUM
(2022)
Review
Orthopedics
Andrew D. Gailey, Robert F. Ostrum
Summary: The use of liposomal bupivacaine in fracture patients lacks clear evidence, requiring prospective, randomized clinical trials for further evaluation. Clinicians should maintain a healthy skepticism and rely on their own interpretation of the available data before widely implementing the use of liposomal bupivacaine.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Review
Multidisciplinary Sciences
Natasha C. Brigham, Ru-Rong Ji, Matthew L. Becker
Summary: The study reviews the use of polymeric materials in post-operative pain management devices and highlights opportunities for improvement in current systems. Pain management plays a significant role in patient comfort, care quality, and compliance.
NATURE COMMUNICATIONS
(2021)
Review
Nursing
Nahadja Tahaynara Barros Leal, Naryllenne Maciel de Araujo, Silmara de Oliveira Silva, Maria Amellia Lopes Cabral, Bruna Vilar Soares da Silva, Thais Brunna Mauricio Pinheiro, Rodrigo Assis Neves Dantas, Daniele Vieira Dantas
Summary: This study aimed to map the scientific evidence on pain management in patients in the postoperative period of amputation surgeries. The results showed that pharmacological measures and neurostimulation techniques were effective strategies for pain management, but more research on non-pharmacological measures is needed.
JOURNAL OF CLINICAL NURSING
(2023)