Fully automated counting of DNA damage foci in tumor cell culture: A matter of cell separation

FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy

(2020) Simon Memmel et al.   BMC BIOINFORMATICS

A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer

(2018) Sabrina Köcher et al.   INTERNATIONAL JOURNAL OF CANCER

AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair

(2018) Nicor Lengert et al.   Scientific Reports

Impact of in Vivo High-Field-Strength and Ultra-High-Field-Strength MR Imaging on DNA Double-Strand-Break Formation in Human Lymphocytes

(2017) Annika Reddig et al.   RADIOLOGY

Radiation dose determines the method for quantification of DNA double strand breaks

(2016) TANJA BULAT et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice

(2016) Ali Bakr et al.   RADIOTHERAPY AND ONCOLOGY

Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes

(2015) Annika Reddig et al.   PLoS One

The Focinator - a new open-source tool for high-throughput foci evaluation of DNA damage

(2015) Sebastian Oeck et al.   Radiation Oncology

Residual γH2AX foci after ex vivo irradiation of patient samples with known tumour-type specific differences in radio-responsiveness

(2015) Apostolos Menegakis et al.   RADIOTHERAPY AND ONCOLOGY

γH2AX assay in ex vivo irradiated tumour specimens: A novel method to determine tumour radiation sensitivity in patient-derived material

(2015) Apostolos Menegakis et al.   RADIOTHERAPY AND ONCOLOGY

DNA Damage Response Assessments in Human Tumor Samples Provide Functional Biomarkers of Radiosensitivity

(2015) Henning Willers et al.   SEMINARS IN RADIATION ONCOLOGY

Functional Ex Vivo Assay to Select Homologous Recombination-Deficient Breast Tumors for PARP Inhibitor Treatment

(2014) K. A. T. Naipal et al.   CLINICAL CANCER RESEARCH

Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells

(2014) Annika Kötter et al.   Molecular Oncology

Fully automated analysis of chemically induced γH2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence

(2013) Annika Willitzki et al.   CYTOMETRY PART A

Manual versus automated γ-H2AX foci analysis across five European laboratories: Can this assay be used for rapid biodosimetry in a large scale radiation accident?

(2013) Kai Rothkamm et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Laboratory Intercomparison on the γ-H2AX Foci Assay

(2013) K. Rothkamm et al.   RADIATION RESEARCH

Fully automated interpretation of ionizing radiation-induced γH2AX foci by the novel pattern recognition system AKLIDES®

(2012) Roswitha Runge et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase

(2012) Sabrina Köcher et al.   NUCLEIC ACIDS RESEARCH

Early Increase of Radiation-induced γH2AX Foci in a Human Ku70/80 Knockdown Cell Line Characterized by an Enhanced Radiosensitivity

(2010) Veerle VANDERSICKEL et al.   JOURNAL OF RADIATION RESEARCH

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair

(2008) Ulla Kasten-Pisula et al.   RADIOTHERAPY AND ONCOLOGY