Review
Cardiac & Cardiovascular Systems
Pishoy Gouda, Justin Ezekowitz
Summary: The use of electronic medical records has provided new opportunities for cardiovascular research, such as improving quality of care and examining genetic and pharmacological associations. However, further assessment of true clinical utility is needed before fully embracing these opportunities.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
(2023)
Article
Clinical Neurology
K. Pun, C. W. Zhu, M. T. Kinsella, M. Sewell, H. Grossman, J. Neugroschl, C. Li, A. Ardolino, N. Velasco, M. Sano
Summary: Recruiting older individuals for research on cognitive health and aging via mail was moderately successful, with a response rate of 6.0% and an enrollment rate of 0.2% out of 15,952 recipients. Although utilizing EHR did not improve study enrollment, the comparison group yielded higher enrollment rates.
JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE
(2021)
Article
Computer Science, Information Systems
Nyiramugisha K. Niyibizi, Candace D. Speight, Charlie Gregor, Yi-An Ko, Stephanie A. Kraft, Andrea R. Mitchell, Bradley G. Phillips, Kathryn M. Porter, Seema K. Shah, Jeremy Sugarman, Benjamin S. Wilfond, Neal W. Dickert
Summary: Through an online experimental survey, we found that participants are most concerned about information, privacy, and having enough time to think in an authorization for contact (AFC) program, with specific clusters having concerns about privacy, lack of interest in research, and not wanting to be bothered. A novel flyer with a simple and positive framing was associated with lower odds of not wanting to be bothered and not being interested in research, suggesting it may be a more effective recruitment tool.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Article
Medicine, Research & Experimental
David Dunn, Leanne McCabe, Ellen White, Valerie Delpech, Peter D. Kirwan, Jameel Khawam, Sara Croxford, Denise Ward, Elizabeth Brodnicki, Alison Rodger, Sheena McCormack
Summary: This article describes the experience of using electronic health records (EHRs) to capture primary outcomes in two randomized HIV prevention trials in the UK. Linkage to the UKHSA database was crucial for capturing HIV diagnoses and ensuring the success of the trials.
Article
Health Care Sciences & Services
Wen Shi, Shobna Vasishta, Louise Dow, Daniella Cavellini, Colin Palmer, Brian McKinstry, Frank Sullivan
Summary: SHARE provides recruitment support services for researchers, utilizing patients' Electronic Health Records (EHRs) for participant recruitment. The evaluation of SHARE's performance in recruitment showed potential for improvement in expanding the registrant base and incorporating more data into candidate-searching processes.
BMC MEDICAL RESEARCH METHODOLOGY
(2021)
Article
Psychology, Developmental
Gabrielle F. Duhon, Andrea R. Simon, Danica L. Limon, Kelli L. Ahmed, Gabriela Marzano, Robin P. Goin-Kochel
Summary: The success of a targeted best practice alert (BPA) in recruiting underrepresented families into an autism spectrum disorder research cohort was evaluated. The findings indicate that a targeted BPA can help researchers access more diverse groups and improve equitable representation, but also suggest potential selection bias among pediatricians in determining who should receive information about study opportunities.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Review
Public, Environmental & Occupational Health
Ingridy M. P. Barbalho, Felipe Fernandes, Daniele M. S. Barros, Jailton C. Paiva, Jorge Henriques, Antonio H. F. Morais, Karilany D. Coutinho, Giliate C. Coelho Neto, Arthur Chioro, Ricardo A. M. Valentim
Summary: This paper presents an audit of the main approaches used for Electronic Health Records (EHR) development in Brazil, discussing prospects, challenges, and existing gaps. The analysis highlights the importance of interoperability, data security, and defined development methodologies.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Ramesh Nadarajah, Jianhua Wu, David Hogg, Keerthenan Raveendra, Yoko M. Nakao, Kazuhiro Nakao, Ronen Arbel, Moti Haim, Doron Zahger, John Parry, Chris Bates, Campbel Cowan, Chris P. Gale
Summary: A machine learning algorithm called FIND-AF was developed to predict the risk of incident atrial fibrillation (AF) within 6 months using primary care data. The algorithm outperformed existing scores in predicting AF and can be applied at scale in routine practice.
Article
Information Science & Library Science
Indranil R. Bardhan, Chenzhang Bao, Sezgin Ayabakan
Summary: This study investigates the impact of hospitals' electronic health records (EHR) sourcing strategies on healthcare value. The findings suggest that hospitals with single-vendor EHR configurations have better health information sharing compared to hospitals with multi-vendor systems. The integration between hospitals and physician practices moderates the effect of single sourcing on health information sharing, ultimately improving value in healthcare.
INFORMATION SYSTEMS RESEARCH
(2022)
Editorial Material
Health Care Sciences & Services
Roseann S. Gammal, Lucas A. Berenbrok, Philip E. Empey, Mylynda B. Massart
Summary: The article highlights the importance of documenting pharmacogenomic test results in a patient's electronic health record, especially in the absence of dedicated clinical pharmacogenomics teams and support. Practical tips are provided for clinicians to maximize the visibility and utility of these results over time.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Clinical Neurology
C. Mary Vance, M. Myron Chang, B. Jeremy Sussman, Kara Zivin, N. Paul Pfeiffer
Summary: This study evaluated clinical prediction models estimating the response likelihood of primary care treatment for depression in the VA healthcare system. The model performance did not support its use in clinical decision-making, suggesting the need for future research to explore obtaining additional risk factor data from patients or modeling PHQ-9 scores over a narrower time interval to improve the performance of clinical risk prediction tools for depression.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Medicine, Research & Experimental
Emily C. O'Brien, Sudha R. Raman, Alicia Ellis, Bradley G. Hammill, Lisa G. Berdan, Tyrus Rorick, Salim Janmohamed, Zachary Lampron, Adrian F. Hernandez, Lesley H. Curtis
Summary: Although electronic health record screening is commonly used for recruitment in a cardiovascular outcomes trial, there are important technical, governance, and regulatory barriers that need to be addressed to support optimal use of EHR for trial participant identification.
Article
Computer Science, Information Systems
Elsie M. F. Horne, Susannah McLean, Mohammad A. Alsallakh, Gwyneth A. Davies, David B. Price, Aziz Sheikh, Athanasios Tsanas
Summary: This study defined and validated asthma subtypes using large longitudinal primary care electronic health records (EHRs). The results showed that asthma subtypes were primarily defined by the level of steroid use, level of healthcare utilization, and the presence of comorbidities. This has important clinical implications for defining asthma subtypes, facilitating patient stratification, and developing more personalized monitoring and treatment strategies.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2023)
Article
Health Care Sciences & Services
Wendy L. Bennett, Carolyn T. Bramante, Scott D. Rothenberger, Jennifer L. Kraschnewski, Sharon J. Herring, Michelle R. Lent, Jeanne M. Clark, Molly B. Conroy, Harold Lehmann, Nickie Cappella, Megan Gauvey-Kern, Jody McCullough, Kathleen M. McTigue
Summary: The study recruited 1085 patients from 5 health systems, with the highest recruitment efficiency being in-person recruitment, followed by electronic messaging which also recruited more Black patients.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Geriatrics & Gerontology
Paul Campbell, Trishna Rathod-Mistry, Michelle Marshall, James Bailey, Carolyn A. Chew-Graham, Peter Croft, Martin Frisher, Richard Hayward, Rashi Negi, Swaran Singh, Shula Tantalo-Baker, Suhail Tarafdar, Opeyemi O. Babatunde, Louise Robinson, Athula Sumathipala, Nwe Thein, Kate Walters, Scott Weich, Kelvin P. Jordan
Summary: The study identified 63 markers of dementia-related health mapped to 13 domains, with comorbidity and home pressures being the most and least prevalent domains in dementia patients. These markers provide valuable insights into the challenges faced by dementia patients in their daily lives and could be used to identify individuals at risk of faster progression.
AGING & MENTAL HEALTH
(2021)
Article
Primary Health Care
Kelly E. Lloyd, Louise H. Hall, Lucy Ziegler, Robbie Foy, Gillian M. Borthwick, Mairead MacKenzie, David G. Taylor, Samuel G. Smith
Summary: The study investigated the optimal type and level of information to communicate with GPs in order to increase their willingness to prescribe aspirin for Lynch syndrome. The results showed that providing different combinations of information on clinical guidance, trial results, and benefits and harms did not increase GPs' willingness to prescribe aspirin.
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Article
Medicine, General & Internal
Samuel G. Smith, Sophie M. C. Green, Rachel Ellison, Robbie Foy, Christopher D. Graham, Ellen Mason, David P. French, Louise H. Hall, Hollie Wilkes, Emma McNaught, Erin Raine, Rebecca Walwyn, Daniel Howdon, Jane Clark, Nikki Rousseau, Jacqueline Buxton, Sally J. L. Moore, Catherine Parbutt, Galina Velikova, Amanda Farrin, Michelle Collinson
Summary: Women with breast cancer who do not adhere to adjuvant endocrine therapy (AET) have increased risks of mortality and recurrence. Multiple barriers to AET adherence include medication side-effects, beliefs about medication, memory, and psychological distress. This pilot trial aims to establish key trial parameters, intervention component adherence, availability and feasibility of outcome and process data, and cost estimation.
Review
Criminology & Penology
Jenna Blackaby, Jordan Byrne, Sue Bellass, Krysia Canvin, Robbie Foy
Summary: This scoping literature review highlights the lack of high-quality evidence on strategies to implement evidence-based healthcare in prison settings. Most evaluations have focused on priority areas for incarcerated populations, but there is limited attention to long-term conditions relevant to primary care delivery. There is a need for a stronger evidence base to bridge the gap between evidence and practice in prison primary care.
Meeting Abstract
Primary Health Care
Kate McLintock, Robbie Foy, Krysia Canvin, Sue Bellass, Pip Hearty, Nat Wright, Marie Cunningham, Nicola Seanor, Laura Sheard, Tracey Farragher
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Article
Primary Health Care
Laura Sheard, Sue Bellass, Kate Mclintock, Robbie Foy, Krysia Canvin
Summary: This qualitative interview study identified chronic understaffing and its impact as the most significant threat to the quality of and access to primary care in prisons. The study also highlighted the reactive and crisis-led service model, unreliable communication about healthcare matters, and the positive role of individual healthcare professionals.
BRITISH JOURNAL OF GENERAL PRACTICE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Kate P. Kenny, Sue Pavitt, Robbie Foy, Peter F. Day
Summary: Poor recording of diagnostic and treatment codes in clinical dentistry makes it difficult to evaluate the success of dental injury treatment. This study used a sequential, mixed-methods approach to determine the outcomes that should be included in a minimum dataset for traumatic dental injuries. Interviews with patients and a Delphi survey with clinicians were conducted to identify important outcomes, and a consensus meeting involving stakeholders was held to finalize the dataset.
DENTAL TRAUMATOLOGY
(2023)
Article
Health Care Sciences & Services
Michael Sykes, Bethan Copsey, Tracy Finch, David Meads, Amanda Farrin, Jenny Mcsharry, Naomi Holman, Bob Young, Alex Berry, Kat Ellis, Lauren Moreau, Thomas Willis, Sarah Alderson, Melissa Girling, Elaine O'Halloran, Robbie Foy
Summary: This study aims to improve the uptake of insulin pumps among people with type 1 diabetes through a quality improvement collaborative project, and evaluate its effectiveness through data analysis and evaluation.
IMPLEMENTATION SCIENCE
(2023)
Article
Medicine, Research & Experimental
Thomas A. Willis, Alexandra Wright-Hughes, Clare Skinner, Amanda J. Farrin, Suzanne Hartley, Rebecca Walwyn, Ana Weller, Mohamed Althaf, Stephanie Wilson, Chris P. Gale, Robbie Foy
Summary: Online studies offer efficient recruitment and data collection methods, but they are also vulnerable to attempted fraud. This study detected and managed suspected fraud during an online trial, providing valuable lessons for researchers.
Article
Medicine, Research & Experimental
Robbie Foy, Noah M. Ivers, Jeremy M. Grimshaw, Paul M. Wilson
Summary: There is a debate about the role of randomized trials in evaluating implementation strategies, given the emergence of more rigorous quasi-experimental designs. Critiques of trials for implementation science highlight their limitations in providing real-world evidence, addressing important questions, and understanding contextual influences. Suggestions for optimizing the conditions for randomized trials include strengthening partnerships with policy-makers, accelerating ethical approvals, and simplifying governance procedures.
Article
Medicine, Research & Experimental
Rebecca Lawton, Jenni Murray, Ruth Baxter, Gerry Richardson, Sarah Cockayne, Kalpita Baird, Laura Mandefield, Stephen Brealey, Jane O'Hara, Robbie Foy, Laura Sheard, Alison Cracknell, Edmund Breckin, Catherine Hewitt, PACT res team
Summary: This study aims to evaluate the effectiveness and cost-effectiveness of the YCNY intervention in improving patient safety and experience for older people during the transition from hospital to home. Data will be collected and a process evaluation will be conducted to understand the implementation of the intervention and how to optimize it.
Editorial Material
Health Care Sciences & Services
Sarah Alderson, Noah Michael Ivers, Robbie Foy
BMJ QUALITY & SAFETY
(2023)
Article
Medicine, General & Internal
Kate McLintock, Robbie Foy, Krysia Canvin, Sue Bellass, Philippa Hearty, Nat Wright, Marie Cunningham, Nicola Seanor, Laura Sheard, Tracey Farragher
Summary: The study reveals significant room for improvement in the quality of primary care for prisoners, with marked variations that remain even after adjusting for prison and prisoner characteristics.
Article
Hematology
H. G. Evans, M. F. Murphy, R. Foy, P. Dhiman, L. Green, A. Kotze, L. von Neree, A. J. Palmer, S. E. Robinson, A. Shah, F. Tomini, S. Trompeter, S. Warnakulasuriya, W. K. Wong, S. J. Stanworth
Summary: There is significant variation in the practice of transfusion medicine, and the effectiveness and cost-effectiveness of current measures such as education, clinical guidelines, and audit feedback remain unclear. Computerized decision support systems and novel electronic capabilities offer alternative approaches to improving transfusion practice. In England, a research program funded by the National Institute for Health and Care Research focuses on data-driven methods to optimize blood and transfusion alternatives and integrate them into routine practice.
BRITISH JOURNAL OF HAEMATOLOGY
(2023)