Tumor-derived extracellular vesicles containing long noncoding RNA PART1 exert oncogenic effect in hepatocellular carcinoma by polarizing macrophages into M2

Circular RNA TTC3 regulates cerebral ischemia-reperfusion injury and neural stem cells by miR-372-3p/TLR4 axis in cerebral infarction

(2021) Bo Yang et al.   Stem Cell Research & Therapy

LncRNA PART1 facilitates the malignant progression of colorectal cancer via miR‐150‐5p/LRG1 axis

(2020) Tingting Lou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment

(2020) Pei-pei Hou et al.   MOLECULAR CELL

Hepatocellular carcinoma cell-derived extracellular vesicles encapsulated microRNA-584-5p facilitates angiogenesis through PCK1-mediated nuclear factor E2-related factor 2 signaling pathway

(2020) Zigong Shao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Long Noncoding RNA PART1 Promotes Hepatocellular Carcinoma Progression via Targeting miR-590-3p/HMGB2 Axis

(2020) Jian Pu et al.   OncoTargets and Therapy

Construction of a disease‐specific lncRNA‐miRNA‐mRNA regulatory network reveals potential regulatory axes and prognostic biomarkers for hepatocellular carcinoma

(2020) Qi Zhang et al.   Cancer Medicine

Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma

(2019) Ying Jiang et al.   NATURE

Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

(2019) Rongkun Li et al.   Molecular Cancer

TLR 4 increases the stemness and is highly expressed in relapsed human hepatocellular carcinoma

(2019) Shuang Zhou et al.   Cancer Medicine

Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM

(2019) Xia Cheng et al.   Breast Cancer

Over-expression of MiR-122 promotes apoptosis of hepatocellular carcinoma via targeting TLR4

(2019) Xiaolin Wei et al.   Annals of Hepatology

Long noncoding RNA PART1 promotes progression of non‐small cell lung cancer cells via JAK‐STAT signaling pathway

(2019) Dengyan Zhu et al.   Cancer Medicine

LncRNA PART1 modulates toll-like receptor pathways to influence cell proliferation and apoptosis in prostate cancer cells

(2018) Ming Sun et al.   BIOLOGICAL CHEMISTRY

Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages

(2018) Ineta Popēna et al.   Cell Communication and Signaling

Long non-coding RNA expression profile can predict early recurrence in hepatocellular carcinoma after curative resection

(2018) Yufeng Lv et al.   HEPATOLOGY RESEARCH

Hepatocellular carcinoma

(2018) Alejandro Forner et al.   LANCET

Neurotensin/IL-8 pathway orchestrates local inflammatory response and tumor invasion by inducing M2 polarization of Tumor-Associated macrophages and epithelial-mesenchymal transition of hepatocellular carcinoma cells

(2018) Pei Xiao et al.   OncoImmunology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism

(2018) Ting Chen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA

(2018) Min Kang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Tumour exosomes from cells harbouring PTPRZ1–MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma

(2017) A-L Zeng et al.   ONCOGENE

Long noncoding RNA, the methylation of genomic elements and their emerging crosstalk in hepatocellular carcinoma

(2016) Sheng-xian Yuan et al.   CANCER LETTERS

Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10

(2016) Aditya Ambade et al.   OncoImmunology

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY