Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors

A Phase 2 Trial of Selumetinib in Children with Recurrent Optic Pathway and Hypothalamic Low-Grade Glioma without NF1: A Pediatric Brain Tumor Consortium Study

(2021) Jason Fangusaro et al.   NEURO-ONCOLOGY

Decoding neuronal composition and ontogeny of individual hypothalamic nuclei

(2021) Tong Ma et al.   NEURON

Advancing RAS/RASopathy therapies: An NCI‐sponsored intramural and extramural collaboration for the study of RASopathies

(2020) Andrea M. Gross et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Implications of New Understandings of Gliomas in Children and Adults with NF1: Report of a Consensus Conference

(2020) Roger J Packer et al.   NEURO-ONCOLOGY

Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas

(2020) Scott Ryall et al.   CANCER CELL

Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution

(2020) Yinghua Li et al.   Nature Communications

Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus

(2020) Xin Zhou et al.   Nature Communications

Costello syndrome: Clinical phenotype, genotype, and management guidelines

(2019) Karen W. Gripp et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

(2019) Zachary J. Reitman et al.   Nature Communications

Serial MRIs provide novel insight into natural history of optic pathway gliomas in patients with neurofibromatosis 1

(2018) Laura Sellmer et al.   Orphanet Journal of Rare Diseases

Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma

(2018) Seçkin Akgül et al.   Cell Reports

The molecular landscape of glioma in patients with Neurofibromatosis 1

(2018) Fulvio D’Angelo et al.   NATURE MEDICINE

Pediatric low-grade gliomas: next biologically driven steps

(2017) David T W Jones et al.   NEURO-ONCOLOGY

Origin of Oligodendrocytes in the Vertebrate Optic Nerve: A Review

(2017) Katsuhiko Ono et al.   NEUROCHEMICAL RESEARCH

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

(2017) Cristian Tomasetti et al.   SCIENCE

Neurofibromatosis type 1

(2017) David H. Gutmann et al.   Nature Reviews Disease Primers

Oligodendrocyte development in the embryonic tuberal hypothalamus and the influence of Ascl1

(2016) Candace M. Marsters et al.   Neural Development

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Development of astrocytes in the vertebrate eye

(2014) Chenqi Tao et al.   DEVELOPMENTAL DYNAMICS

eulerAPE: Drawing Area-Proportional 3-Venn Diagrams Using Ellipses

(2014) Luana Micallef et al.   PLoS One

Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1

(2014) Edward Kim et al.   eLife

Innate Neural Stem Cell Heterogeneity Determines the Patterning of Glioma Formation in Children

(2012) Da Yong Lee et al.   CANCER CELL

ERK Inhibition Rescues Defects in Fate Specification of Nf1-Deficient Neural Progenitors and Brain Abnormalities

(2012) Yuan Wang et al.   CELL

Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis

(2012) M. J. Fisher et al.   NEURO-ONCOLOGY

MEK Is a Key Regulator of Gliogenesis in the Developing Brain

(2012) Xiaoyan Li et al.   NEURON

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature

(2009) A. Tchoghandjian et al.   BRAIN

Expression of Mutant p53 Proteins Implicates a Lineage Relationship between Neural Stem Cells and Malignant Astrocytic Glioma in a Murine Model

(2009) Yuan Wang et al.   CANCER CELL