Why TAPBPR? Implications of an additional player in MHC class I peptide presentation

A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor

(2020) Lina Sagert et al.   eLife

The love and hate relationship of HLA-DM/DO in the selection of immunodominant epitopes

(2020) Robin A Welsh et al.   CURRENT OPINION IN IMMUNOLOGY

Structural and dynamic studies of TAPBPR and Tapasin reveal the mechanism of peptide loading of MHC-I molecules

(2020) David H Margulies et al.   CURRENT OPINION IN IMMUNOLOGY

Atomistic structure and dynamics of the human MHC-I peptide-loading complex

(2020) Olivier Fisette et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HLA tapasin independence: broader peptide repertoire and HIV control

(2020) Arman A. Bashirova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

(2020) Hamish E. G. McWilliam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin

(2019) Ida Hafstrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR

(2019) F. Tudor Ilca et al.   Cell Reports

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

(2018) Andrew C. McShan et al.   Nature Chemical Biology

Preferential interaction of MHC class I with TAPBPR in the absence of glycosylation

(2018) Andreas Neerincx et al.   MOLECULAR IMMUNOLOGY

Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules

(2018) F. Tudor Ilca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

(2018) F Tudor Ilca et al.   eLife

Structure of the human MHC-I peptide-loading complex

(2017) Andreas Blees et al.   NATURE

Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen presentation

(2017) Jiansheng Jiang et al.   SCIENCE

Structure of the TAPBPR–MHC I complex defines the mechanism of peptide loading and editing

(2017) Christoph Thomas et al.   SCIENCE

How MR1 Presents a Pathogen Metabolic Signature to Mucosal-Associated Invariant T (MAIT) Cells

(2017) Hamish E.G. McWilliam et al.   TRENDS IN IMMUNOLOGY

TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway

(2017) Andreas Neerincx et al.   eLife

Recent advances in viral evasion of the MHC Class I processing pathway

(2016) Anouk BC Schuren et al.   CURRENT OPINION IN IMMUNOLOGY

Antigen processing and immune regulation in the response to tumours

(2016) Emma Reeves et al.   IMMUNOLOGY

Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing

(2016) Giora I. Morozov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

F pocket flexibility influences the tapasin dependence of two differentially disease-associated MHC Class I proteins

(2015) Esam T. Abualrous et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

(2015) Clemens Hermann et al.   eLife

TAPBPR isoforms exhibit altered association with MHC class I

(2014) Keith M. Porter et al.   IMMUNOLOGY

Distinct Assembly Profiles of HLA-B Molecules

(2014) S. M. Rizvi et al.   JOURNAL OF IMMUNOLOGY

The Adaptable Major Histocompatibility Complex (MHC) Fold: Structure and Function of Nonclassical and MHC Class I–Like Molecules

(2013) Erin J. Adams et al.   Annual Review of Immunology

Pathways of Antigen Processing

(2013) Janice S. Blum et al.   Annual Review of Immunology

Tapasin Facilitation of Natural HLA-A and -B Allomorphs Is Strongly Influenced by Peptide Length, Depends on Stability, and Separates Closely Related Allomorphs

(2013) L. Geironson et al.   JOURNAL OF IMMUNOLOGY

The Binding of TAPBPR and Tapasin to MHC Class I Is Mutually Exclusive

(2013) C. Hermann et al.   JOURNAL OF IMMUNOLOGY

Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway

(2013) Louise H. Boyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

(2012) Wouter Pos et al.   CELL

HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism

(2012) Abigail I Guce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility

(2011) Malgorzata Anna Garstka et al.   FASEB JOURNAL

Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer

(2009) Gang Dong et al.   IMMUNITY