Hierarchical mesoporous metal-organic frameworks encapsulated enzymes: Progress and perspective

Hierarchical mesoporous metal-organic frameworks (HM-MOFs) with adjustable mesopores have shown great potential for the encapsulation of enzyme because of their enhanced performance for enzymatic catalysis. The evolution of HM-MOFs encapsulated enzymes has resulted in tremendous progress. To date, a considerable number of HM-MOFs featured with intrinsic mesopores or mesoporous defects have been developed for enzyme encapsulation, and significant enhancement has been achieved in terms of catalytic activity, stability, and reusability. This review systematically summarizes the exploitation and strategies to design HM-MOFs. Various strategies for developing enzyme@HM-MOF composites and their advanced applications are also surveyed. Possible future directions in this area are also envisioned and discussed to provide an accessible introduction to HM-MOFs encapsulated enzymes for the scientists in this field. (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

Hierarchical mesoporous metal-organic frameworks (HM-MOFs) with adjustable mesopores have shown great potential for enzyme encapsulation, resulting in significant progress in catalytic activity, stability, and reusability. Possible future directions and strategies in this area have also been discussed to provide an accessible introduction to scientists.