Discovery of new inhibitor for the protein arginine deiminase type 4 (PAD4) by rational design of α-enolase-derived peptides

PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets

(2020) Ashley M. Curran et al.   Nature Reviews Rheumatology

Interleukin-15 as a Biomarker Candidate of Rheumatoid Arthritis Development

(2020) Weronika Kurowska et al.   Journal of Clinical Medicine

The relationship of PADI4_94 polymorphisms with the morbidity of rheumatoid arthritis in Caucasian and Asian populations: a meta-analysis and system review

(2018) Chao Lu et al.   CLINICAL RHEUMATOLOGY

Peptidylarginine deiminase 4 -104C/T polymorphism and risk of rheumatoid arthritis: A pooled analysis based on different populations

(2018) Jiong Hua et al.   PLoS One

Novel treatment strategies in rheumatoid arthritis

(2017) Gerd R Burmester et al.   LANCET

Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004–2014

(2017) Theresa M. Hunter et al.   RHEUMATOLOGY INTERNATIONAL

High-Titer Rheumatoid Arthritis Antibodies Preferentially Bind Fibrinogen Citrullinated by Peptidylarginine Deiminase 4

(2017) Nathalie E. Blachère et al.   Arthritis & Rheumatology

Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice

(2016) Akari Suzuki et al.   BMC MUSCULOSKELETAL DISORDERS

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

Association between susceptibility to rheumatoid arthritis and PADI4 polymorphisms: a meta-analysis

(2015) Young Ho Lee et al.   CLINICAL RHEUMATOLOGY

The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

Improved PEP-FOLD Approach for Peptide and Miniprotein Structure Prediction

(2014) Yimin Shen et al.   Journal of Chemical Theory and Computation

PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides

(2012) P. Thevenet et al.   NUCLEIC ACIDS RESEARCH

Cysteine 351 is an essential nucleophile in catalysis by Porphyromonas gingivalis peptidylarginine deiminase

(2010) Sofía B. Rodríguez et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The lifetime risk of adult-onset rheumatoid arthritis and other inflammatory autoimmune rheumatic diseases

(2010) Cynthia S. Crowson et al.   ARTHRITIS AND RHEUMATISM

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

(2009) Mary-Clare Miller et al.   ARTHRITIS AND RHEUMATISM

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis

(2008) Michelle L. Harris et al.   ARTHRITIS AND RHEUMATISM

Inactivation of Microbial Arginine Deiminases byl-Canavanine

(2008) Ling Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FireDock: a web server for fast interaction refinement in molecular docking

(2008) E. Mashiach et al.   NUCLEIC ACIDS RESEARCH

An important step towards completing the rheumatoid arthritis cycle

(2008) Walther J van Venrooij et al.   ARTHRITIS RESEARCH & THERAPY

Profiling Protein Arginine Deiminase 4 (PAD4): A novel screen to identify PAD4 inhibitors

(2007) Bryan Knuckley et al.   BIOORGANIC & MEDICINAL CHEMISTRY