Sex-differential heterologous (non-specific) effects of vaccines: an emerging public health issue that needs to be understood and exploited

Changing oral vaccine to inactivated polio vaccine might increase mortality

(2016) Eleanor N Fish et al.   LANCET

Impact of Adjuvant Intravesical Bacillus Calmette-Guérin Treatment on Patients with High-Grade T1 Bladder Cancer

(2016) Vladimir Novotny et al.   UROLOGIA INTERNATIONALIS

RTS,S Malaria Vaccine and Increased Mortality in Girls

(2016) Sabra L. Klein et al.   mBio

The Effect of Oral Polio Vaccine at Birth on Infant Mortality: A Randomized Trial

(2015) Najaaraq Lund et al.   CLINICAL INFECTIOUS DISEASES

Low-Dose Versus Standard Dose of Bacillus Calmette-Guerin in the Treatment of Nonmuscle Invasive Bladder Cancer

(2015) Shuxiong Zeng et al.   MEDICINE

Y-linked variation for autosomal immune gene regulation has the potential to shape sexually dimorphic immunity

(2015) Ian C. Kutch et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The heterologous (non-specific) effects of vaccines: implications for policy in high-mortality countries

(2015) F. Shann   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

BCG-associated heterologous immunity, a historical perspective: intervention studies in animal models of infectious diseases

(2015) B. Freyne et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Nanoparticles modify dendritic cell homeostasis and induce non-specific effects on immunity to malaria

(2015) S. D. Xiang et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Vaccination and heterologous immunity: educating the immune system

(2015) Anna Gil et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Oral Polio Vaccination and Hospital Admissions With Non-Polio Infections in Denmark: Nationwide Retrospective Cohort Study

(2015) Signe Sørup et al.   Open Forum Infectious Diseases

Does neonatal BCG vaccination prevent allergic disease in later life?

(2014) B. Freyne et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Immunization with hepatitis B vaccine accelerates SLE-like disease in a murine model

(2014) Nancy Agmon-Levin et al.   JOURNAL OF AUTOIMMUNITY

Mycobacterium bovis Bacille Calmette-Guerin Infection in the CNS Suppresses Experimental Autoimmune Encephalomyelitis and Th17 Responses in an IFN- -Independent Manner

(2014) J. Lee et al.   JOURNAL OF IMMUNOLOGY

Heterologous Immunological Effects of Early BCG Vaccination in Low-Birth-Weight Infants in Guinea-Bissau: A Randomized-controlled Trial

(2014) Kristoffer Jarlov Jensen et al.   JOURNAL OF INFECTIOUS DISEASES

Policy: NIH to balance sex in cell and animal studies

(2014) Janine A. Clayton et al.   NATURE

Nonspecific effects of neonatal and infant vaccination: public-health, immunological and conceptual challenges

(2014) Peter Aaby et al.   NATURE IMMUNOLOGY

Systems vaccinology: Probing humanity's diverse immune systems with vaccines

(2014) B. Pulendran   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sexual dimorphism in biomedical research: a call to analyse by sex

(2014) K. L. Flanagan   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Heterologous and sex differential effects of administering vitamin A supplementation with vaccines

(2014) K. J. Jensen et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Increased emergency room visits or hospital admissions in females after 12-month MMR vaccination, but no difference after vaccinations given at a younger age

(2014) Kumanan Wilson et al.   VACCINE

Bacillus Calmette-Guérin Suppresses Asthmatic Responses via CD4+CD25+Regulatory T Cells and Dendritic Cells

(2014) Young-Joon Kim et al.   Allergy Asthma & Immunology Research

Childhood vaccination associated adverse events by sex: A literature review

(2014) Sandra Köhli Weber et al.   Travel Medicine and Infectious Disease

Heterologous ("Nonspecific") and Sex-Differential Effects of Vaccines: Epidemiology, Clinical Trials, and Emerging Immunologic Mechanisms

(2013) K. L. Flanagan et al.   CLINICAL INFECTIOUS DISEASES

The effects of engineered nanoparticles on pulmonary immune homeostasis

(2013) Rohimah Mohamud et al.   DRUG METABOLISM REVIEWS

Differential Uptake of Nanoparticles and Microparticles by Pulmonary APC Subsets Induces Discrete Immunological Imprints

(2013) C. L. Hardy et al.   JOURNAL OF IMMUNOLOGY

Transcriptional profiling technology for studying vaccine responses: An untapped goldmine

(2013) K.L. Flanagan et al.   METHODS

Effects of Bacille Calmette-Guerin after the first demyelinating event in the CNS

(2013) G. Ristori et al.   NEUROLOGY

Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination

(2013) D. Furman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Personalized vaccinology: One size and dose might not fit both sexes

(2013) Sabra L. Klein et al.   VACCINE

Immediate hypersensitivity reactions following monovalent 2009 pandemic influenza A (H1N1) vaccines: Reports to VAERS

(2013) Neal A. Halsey et al.   VACCINE

Non-specific effect of Bacille Calmette-Guérin vaccine on the immune response to routine immunisations

(2013) Nicole Ritz et al.   VACCINE

Co-administration of live measles and yellow fever vaccines and inactivated pentavalent vaccines is associated with increased mortality compared with measles and yellow fever vaccines only. An observational study from Guinea-Bissau

(2013) Ane Bærent Fisker et al.   VACCINE

Vaccine administration and the development of immune thrombocytopenic purpura in children

(2013) Valerio Cecinati et al.   Human Vaccines & Immunotherapeutics

Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial

(2012) Peter Aaby et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination

(2012) Steven G. Smith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Proof-of-Concept, Randomized, Controlled Clinical Trial of Bacillus-Calmette-Guerin for Treatment of Long-Term Type 1 Diabetes

(2012) Denise L. Faustman et al.   PLoS One

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Testing the hypothesis that diphtheria–tetanus–pertussis vaccine has negative non-specific and sex-differential effects on child survival in high-mortality countries

(2012) Peter Aaby et al.   BMJ Open

Heterologous immunity: Immunopathology, autoimmunity and protection during viral infections

(2011) Liisa K. Selin et al.   AUTOIMMUNITY

X-chromosome-located microRNAs in immunity: Might they explain male/female differences?

(2011) Iris Pinheiro et al.   BIOESSAYS

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Role of bacillus Calmette–Guérin in the treatment of advanced melanoma

(2011) John H Stewart et al.   Expert Review of Anticancer Therapy

Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study

(2011) Signe Sørup et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Randomized Trial of BCG Vaccination at Birth to Low-Birth-Weight Children: Beneficial Nonspecific Effects in the Neonatal Period?

(2011) Peter Aaby et al.   JOURNAL OF INFECTIOUS DISEASES

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

The non-specific effects of vaccines

(2010) F. Shann   ARCHIVES OF DISEASE IN CHILDHOOD

The Xs and Y of immune responses to viral vaccines

(2010) Sabra L Klein et al.   LANCET INFECTIOUS DISEASES

Neonatal BCG vaccination induces IL-10 production by CD4+ CD25+ T cells

(2010) Tunc Akkoc et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Simultaneous Administration of Vitamin A and DTP Vaccine Modulates the Immune Response in a Murine Cerebral Malaria Model

(2010) L. Hein-Kristensen et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

A possible mechanism of intravesical BCG therapy for human bladder carcinoma: involvement of innate effector cells for the inhibition of tumor growth

(2009) Tomoe Higuchi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Does BCG vaccination protect against the development of childhood asthma? A systematic review and meta-analysis of epidemiological studies

(2009) M. El-Zein et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Molecular Analyte Profiling of the Early Events and Tissue Conditioning Following Intravesical Bacillus Calmette-Guerin Therapy in Patients With Superficial Bladder Cancer

(2009) Aurélie Bisiaux et al.   JOURNAL OF UROLOGY

Transverse myelitis and vaccines: a multi-analysis

(2009) N. Agmon-Levin et al.   LUPUS

Ten cases of systemic lupus erythematosus related to hepatitis B vaccine

(2009) N. Agmon-Levin et al.   LUPUS

Adjuvants and autoimmunity

(2009) E. Israeli et al.   LUPUS

Vaccines and autoimmunity

(2009) Nancy Agmon-Levin et al.   Nature Reviews Rheumatology

Risk of lymphoma and leukaemia after bacille Calmette-Guérin and smallpox vaccination: A Danish case-cohort study

(2009) Marie Villumsen et al.   VACCINE

Personalized vaccines: the emerging field of vaccinomics

(2008) Gregory A Poland et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma

(2008) Kara L. McDonald et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Adverse event reports following yellow fever vaccination

(2008) Nicole P. Lindsey et al.   VACCINE

Sexual dimorphism of humoral immunity with human vaccines

(2008) Ian Francis Cook   VACCINE