Proteomic analysis ofAspergillus fumigatus– clinical implications

Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA

(2016) Elke R. Duell et al.   ACS Chemical Biology

The glycolytic enzyme enolase represents a plasminogen-binding protein on the surface of a wide variety of medically important fungal species

(2016) Jana Funk et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance

(2016) Neil A. Brown et al.   JOURNAL OF MICROBIOLOGY

Recent advances in the understanding of the Aspergillus fumigatus cell wall

(2016) Mark J. Lee et al.   JOURNAL OF MICROBIOLOGY

Proteomic Profiling of Serological Responses to Aspergillus fumigatus Antigens in Patients with Invasive Aspergillosis

(2016) Janka Teutschbein et al.   JOURNAL OF PROTEOME RESEARCH

The iron-responsive microsomal proteome of Aspergillus fumigatus

(2016) Nicola M. Moloney et al.   Journal of Proteomics

The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence ofAspergillus fumigatus

(2016) Kristin Kroll et al.   MOLECULAR MICROBIOLOGY

FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection

(2016) Sheena C. Kerr et al.   PLoS Pathogens

Breaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategy

(2015) Audrey L. Lamb   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model

(2015) S. Namvar et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Activity-based protein profiling of microbes

(2015) Natalie C Sadler et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus

(2015) Rebecca A. Owens et al.   EUKARYOTIC CELL

A monoclonal antibody against glycoproteins of Aspergillus fumigatus shows anti-adhesive potential

(2015) Awanit Kumar et al.   MICROBIAL PATHOGENESIS

Proteomics of hosts and pathogens in cystic fibrosis

(2015) Karthik Shantharam Kamath et al.   Proteomics Clinical Applications

Resistance is not futile: gliotoxin biosynthesis, functionality and utility

(2015) Stephen K. Dolan et al.   TRENDS IN MICROBIOLOGY

A fungal protease allergen provokes airway hyper-responsiveness in asthma

(2015) Nariman A. Balenga et al.   Nature Communications

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

Cycloaspeptide A and Pseurotin A from the Endophytic Fungus Penicillium janczewskii

(2015) Guillermo Schmeda-Hirschmann et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus

(2014) Grainne O’Keeffe et al.   BMC GENOMICS

Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus

(2014) Stephen K. Dolan et al.   CHEMISTRY & BIOLOGY

The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine

(2014) Gary W. Jones et al.   GENE

Immunoproteome of Aspergillus fumigatus Using Sera of Patients with Invasive Aspergillosis

(2014) Emylli Virginio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of Immunogenic Antigens fromAspergillus fumigatusby Direct Multiparameter Characterization of Specific Conventional and Regulatory CD4+T Cells

(2014) Petra Bacher et al.   JOURNAL OF IMMUNOLOGY

Opposed Effects of Enzymatic Gliotoxin N- and S-Methylations

(2014) Daniel H. Scharf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fungal siderophore metabolism with a focus on Aspergillus fumigatus

(2014) Hubertus Haas   NATURAL PRODUCT REPORTS

A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus

(2014) Rebecca A. Owens et al.   PLoS One

Interference of Aspergillus fumigatus with the immune response

(2014) Thorsten Heinekamp et al.   Seminars in Immunopathology

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Protein Analysis by Shotgun/Bottom-up Proteomics

(2013) Yaoyang Zhang et al.   CHEMICAL REVIEWS

Adhesins in Human Fungal Pathogens: Glue with Plenty of Stick

(2013) Piet W. J. de Groot et al.   EUKARYOTIC CELL

conF and conJ contribute to conidia germination and stress response in the filamentous fungus Aspergillus nidulans

(2013) Satoshi Suzuki et al.   FUNGAL GENETICS AND BIOLOGY

Mutations in the Chromodomain-like Insertion of Translation Elongation Factor 3 Compromise Protein Synthesis through Reduced ATPase Activity

(2013) Arjun N. Sasikumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular characterization of AfuFleA, an l-fucose-specific lectin from Aspergillus fumigatus

(2013) Satoshi Kuboi et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity

(2013) Josef Houser et al.   PLoS One

Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bγ deletion inAspergillus fumigatus

(2013) Grainne O'Keeffe et al.   PROTEIN SCIENCE

Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

(2013) Kyung J. Kwon-Chung et al.   PLoS Pathogens

Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus

(2013) Anne Beauvais et al.   PLoS Pathogens

Investigation of Aspergillus fumigatus biofilm formation by various “omics” approaches

(2013) Laetitia Muszkieta   Frontiers in Microbiology

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

(2013) Thorsten Heinekamp et al.   Frontiers in Microbiology

Luciferase-Based Assay for Adenosine: Application to S-Adenosyl-l-homocysteine Hydrolase

(2012) Emmanuel S. Burgos et al.   ANALYTICAL CHEMISTRY

Protein targets for broad-spectrum mycosis vaccines: quantitative proteomic analysis ofAspergillusandCoccidioidesand comparisons with other fungal pathogens

(2012) Jackson Champer et al.   Annals of the New York Academy of Sciences

Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter

(2012) Bridget M Barker et al.   BMC GENOMICS

Immunoproteomics based identification of thioredoxin reductase GliT and novel Aspergillus fumigatus antigens for serologic diagnosis of invasive aspergillosis

(2012) Li-ning Shi et al.   BMC MICROBIOLOGY

Antibody specific to thioredoxin reductase as a new biomarker for serodiagnosis of invasive aspergillosis in non-neutropenic patients

(2012) Li-ning Shi et al.   CLINICA CHIMICA ACTA

Heat Shock Protein 90 Is Required for Conidiation and Cell Wall Integrity in Aspergillus fumigatus

(2012) Frédéric Lamoth et al.   EUKARYOTIC CELL

Hypoxia and Fungal Pathogenesis: To Air or Not To Air?

(2012) Nora Grahl et al.   EUKARYOTIC CELL

Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging

(2012) Milos Petrik et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates

(2012) Edward Farnell et al.   Fungal Biology

Gliotoxin effects on fungal growth: Mechanisms and exploitation

(2012) Stephen Carberry et al.   FUNGAL GENETICS AND BIOLOGY

Fungi and allergic lower respiratory tract diseases

(2012) Alan P. Knutsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Multiplexed Activity-based Protein Profiling of the Human PathogenAspergillus fumigatusReveals Large Functional Changes upon Exposure to Human Serum

(2012) Susan D. Wiedner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Characterization of Aspergillus fumigatus Treated with an Antifungal Coumarin for Identification of Novel Target Molecules of Key Pathways

(2012) Seema Singh et al.   JOURNAL OF PROTEOME RESEARCH

Differential proteomic analysis of Aspergillus fumigatus morphotypes reveals putative drug targets

(2012) Paula H. Kubitschek-Barreira et al.   Journal of Proteomics

Transcriptional and Proteomic Analysis of the Aspergillus fumigatus ΔprtT Protease-Deficient Mutant

(2012) Shelly Hagag et al.   PLoS One

Development stage-specific proteomic profiling uncovers small, lineage specific proteins most abundant in the Aspergillus Fumigatus conidial proteome

(2012) Moo-Jin Suh et al.   Proteome Science

Reshuffling of Aspergillus fumigatus Cell Wall Components Chitin and β-Glucan under the Influence of Caspofungin or Nikkomycin Z Alone or in Combination

(2011) Patricia E. B. Verwer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens

(2011) Rupanjali Chaudhuri et al.   BMC GENOMICS

Molecular mechanism of Aspergillus fumigatus adherence to host constituents

(2011) Donald C Sheppard   CURRENT OPINION IN MICROBIOLOGY

Fungal proteomics: from identification to function

(2011) Sean Doyle   FEMS MICROBIOLOGY LETTERS

Identification of virulence determinants of the human pathogenic fungi Aspergillus fumigatus and Candida albicans by proteomics

(2011) Olaf Kniemeyer et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein

(2011) Dirk Wartenberg et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Analysis of theAspergillus fumigatusProteome Reveals Metabolic Changes and the Activation of the Pseurotin A Biosynthesis Gene Cluster in Response to Hypoxia

(2011) Martin Vödisch et al.   JOURNAL OF PROTEOME RESEARCH

Identification of virulence factors and diagnostic markers using immunosecretome of Aspergillus fumigatus

(2011) Awanit Kumar et al.   Journal of Proteomics

The Proteomic Signature ofAspergillus fumigatusDuring Early Development

(2011) Steven E. Cagas et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification of Fibrinogen-Binding Proteins of Aspergillus fumigatus Using Proteomic Approach

(2011) Santosh Kumar Upadhyay et al.   MYCOPATHOLOGIA

Transcriptomic and Proteomic Profile of Aspergillus fumigatus on Exposure to Artemisinin

(2011) Poonam Gautam et al.   MYCOPATHOLOGIA

Fungal Proteases and Their Pathophysiological Effects

(2011) Iwona Yike   MYCOPATHOLOGIA

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Profiling theAspergillus fumigatusProteome in Response to Caspofungin

(2010) Steven E. Cagas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Integrative analysis of the heat shock response in Aspergillus fumigatus

(2010) Daniela Albrecht et al.   BMC GENOMICS

Tasting the fungal cell wall

(2010) Jean-Paul Latgé   CELLULAR MICROBIOLOGY

Analysis of the cellular Aspergillus fumigatus proteome that reacts with sera from rabbits developing an acquired immunity after experimental aspergillosis

(2010) Abdul R. Asif et al.   ELECTROPHORESIS

Regulation of secondary metabolism by chromatin structure and epigenetic codes

(2010) Joseph Strauss et al.   FUNGAL GENETICS AND BIOLOGY

Secreted Aspergillus fumigatus Protease Alp1 Degrades Human Complement Proteins C3, C4, and C5

(2010) J. Behnsen et al.   INFECTION AND IMMUNITY

Metabolic Response to Iron Deficiency in Saccharomyces cerevisiae

(2010) Minoo Shakoury-Elizeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

68Ga-Siderophores for PET Imaging of Invasive Pulmonary Aspergillosis: Proof of Principle

(2010) M. Petrik et al.   JOURNAL OF NUCLEAR MEDICINE

Immuno-Reactive Molecules Identified from the Secreted Proteome ofAspergillus fumigatus

(2010) Bharat Singh et al.   JOURNAL OF PROTEOME RESEARCH

Proteome Profiling and Functional Classification of Intracellular Proteins from Conidia of the Human-Pathogenic MoldAspergillus fumigatus

(2010) Janka Teutschbein et al.   JOURNAL OF PROTEOME RESEARCH

Novel Cytosolic Allergens ofAspergillus fumigatusIdentified from Germinating Conidia

(2010) Bharat Singh et al.   JOURNAL OF PROTEOME RESEARCH

Transannular Disulfide Formation in Gliotoxin Biosynthesis and Its Role in Self-Resistance of the Human PathogenAspergillus fumigatus

(2010) Daniel H. Scharf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Developing a vaccine against aspergillosis

(2010) David A. Stevens et al.   MEDICAL MYCOLOGY

Clinical risk factors for invasive aspergillosis

(2010) John W. Baddley   MEDICAL MYCOLOGY

Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin

(2010) Sandra Bruns et al.   PROTEOMICS

Proteomics by Mass Spectrometry: Approaches, Advances, and Applications

(2009) John R. Yates et al.   Annual Review of Biomedical Engineering

Pseurotin A and its analogues as inhibitors of immunoglobuline E production

(2009) Minoru Ishikawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

(2009) T. R. T. Dagenais et al.   CLINICAL MICROBIOLOGY REVIEWS

A Regulator of Aspergillus fumigatus Extracellular Proteolytic Activity Is Dispensable for Virulence

(2009) A. Bergmann et al.   INFECTION AND IMMUNITY

Transcription Factor PrtT Controls Expression of Multiple Secreted Proteases in the Human Pathogenic Mold Aspergillus fumigatus

(2009) H. Sharon et al.   INFECTION AND IMMUNITY

Identification and characterization of a laminin-binding protein of Aspergillus fumigatus: extracellular thaumatin domain protein (AfCalAp)

(2009) S. K. Upadhyay et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Vaccine progress

(2009) James I. Ito et al.   MEDICAL MYCOLOGY

Proteome Analysis of Aspergillus fumigatus Total Membrane Proteins Identifies Proteins Associated with the Glycoconjugates and Cell Wall Biosynthesis Using 2D LC-MS/MS

(2009) Haomiao Ouyang et al.   MOLECULAR BIOTECHNOLOGY

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus

(2009) Martin Vödisch et al.   PROTEOMICS

Proteomic and Transcriptomic Analysis of Aspergillus fumigatus on Exposure to Amphotericin B

(2008) P. Gautam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Elongation Factor 3, EF3, Associates with the Calcium Channel Cch1 and Targets Cch1 to the Plasma Membrane inCryptococcus neoformans

(2008) Min Liu et al.   EUKARYOTIC CELL

Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils

(2008) Janyce A. Sugui et al.   PLoS One

Cell surface glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of Lactobacillus plantarum LA 318 recognizes human A and B blood group antigens

(2008) Hideki Kinoshita et al.   RESEARCH IN MICROBIOLOGY

Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis

(2008) Andrew McDonagh et al.   PLoS Pathogens