Article
Nanoscience & Nanotechnology
Xiaohui Ni, Yang Jiao, Baisheng Cai, Renbao Liu, Kaihang Lu, Pengpeng Zhang, Xingling Wu, Quanming Zhao
Summary: Surface modification of biomedical titanium is crucial for improving its osteogenic and antibacterial properties. In this study, a microporous magnesium-doped titanium dioxide coating with good antibacterial activity was successfully prepared. The coating promoted cell proliferation and differentiation, while inhibiting the growth of pathogenic bacteria.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Bo Zhang, Jun Feng, Shuo Chen, Ruohan Liao, Chengdong Zhang, Xuwei Luo, Zelong Yang, Dongqin Xiao, Kui He, Ke Duan
Summary: In this study, a magnesium (Mg)-incorporating tantalum (Ta) coating was deposited on a 3D Ti6Al4V scaffold using a sol-gel method for enhancing its osteogenic properties. The results showed that the Mg-incorporating Ta2O5 coating exhibited significantly improved cell proliferation, osteogenic gene expression, and bone ingrowth compared to the uncoated scaffold.
Article
Engineering, Environmental
Yulu Yang, Ju Liu, Maowen Chen, Pengfei Gao, Yi Gong, Rui Chen, Yu Tang, Weihu Yang, Kaiyong Cai
Summary: This study developed a novel strategy for Ti implants based on photolithography, achieving near-infrared light-controlled loading, releasing, and clearing of antimicrobial agents. In vitro antibacterial evaluation and cell experiments demonstrated that the modified Ti substrate exhibited excellent antibacterial and osteoinductive abilities. This work may provide a promising strategy for dynamic orthopedic applications.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Materials Science, Biomaterials
Yue He, Mengyu Yao, Jielong Zhou, Juning Xie, Changxiang Liang, Dong Yin, Shuaihao Huang, Yu Zhang, Feng Peng, Shi Cheng
Summary: This study investigates the effects of nano-structure combined with bioactive ions release on macrophage polarization, osteogenesis, and angiogenesis. The results show that the nano-Mg(OH)(2) film coated Ti surface is more favorable for macrophages polarizing to tissue healing M2 phenotype. In vivo experiments also confirm that the nano-Mg(OH)(2) film induces milder inflammation and thinner fibrous layer compared to untreated Ti. Moreover, the macrophages-conditioned culture medium collected from the nano-Mg(OH)(2) coated Ti group enhances the osteogenic and angiogenic behaviors of bone marrow stem cells and human umbilical vein endothelial cells.
REGENERATIVE BIOMATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Litao Yao, Haiyan Wang, Li Li, Zheng Cao, Yilong Dong, Lili Yao, Weiwei Lou, Shutian Zheng, Yizuo Shi, Xinkun Shen, Chunyuan Cai, Lieping Sheng
Summary: This study focuses on the development of dental implants with a dual-layer coating of silver and strontium titanate, which can effectively promote osteogenesis and exhibit antibacterial properties.
MATERIALS & DESIGN
(2022)
Article
Chemistry, Physical
Yunhui Si, Huanyao Liu, Mengsha Li, Xuzhou Jiang, Hongying Yu, Dongbai Sun
Summary: In this study, a metal-organic framework (MOF) based drug delivery platform was used to modify titanium implants, providing them with antibacterial activity, biocompatibility, and osteogenesis-promoting properties. The modified implants released Zn2+ and MV, which caused oxidative damage to E. coli and S. aureus, inhibiting bacterial proliferation. Furthermore, the MV@ZIF-8 coating promoted osteogenic differentiation of human bone mesenchymal stem cells by activating the canonical Wnt/b-catenin signaling pathway. This research demonstrates the potential application of MOF-based drug delivery platforms in bone tissue engineering.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Review
Chemistry, Applied
Yingchao Xu, Yunting Guo, Guangyu Li, Jianshe Lian
Summary: Phytic acid coating can improve the corrosion resistance of magnesium alloy, possess osteogenic inducement and environmental friendliness, and plays a significant role in improving the integrity of temporary repair implants for implant materials.
PROGRESS IN ORGANIC COATINGS
(2022)
Review
Chemistry, Applied
Yingchao Xu, Yunting Guo, Guangyu Li, Jianshe Lian
Summary: This paper reviews the research progress of phytic acid (PA) coating on biodegradable magnesium (Mg) alloys. The PA conversion coating can improve the corrosion resistance of the Mg matrix while also promoting osteogenesis and being environmentally friendly. The article discusses the structure of PA, the factors influencing the coating, and the strategy of combining with other coatings to enhance its performance.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Engineering, Biomedical
Xiaojing Zhang, Weina Wang, Jia Chen, Min Lai
Summary: In this study, a micro/nanostructured titanium surface was created by dual-acid treatment and anodic oxidation, and then coated with GelMA hydrogel loaded with GL13K to develop anti-bacterial titanium implants. The results showed that the modified titanium surface had good biocompatibility, promoted osteoblast differentiation, and prevented the growth of gram-positive and gram-negative bacteria by the release of GL13K.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2023)
Article
Biophysics
Zheng Wang, Li Mei, Xinqiang Liu, Qihui Zhou
Summary: Hierarchically hybrid biocoatings on Ti implants are developed in this study by incorporating polydopamine, ZnO nanoparticles, and chitosan/nanocrystal hydroxyapatite. These coatings enhance antibacterial activity and osteogenesis, offering a promising alternative for developing Ti implants with long-lifetime bioactivity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biophysics
Yunhui Si, Huanyao Liu, Hongying Yu, Xuzhou Jiang, Dongbai Sun
Summary: In this study, a metal-organic framework derived CuO@ZnO composite was coated onto polydopamine modified titanium alloy, which exhibits antibacterial properties by inhibiting bacterial biofilm formation and sterilizing Staphylococcus aureus. Moreover, it promotes the adhesion and proliferation of human bone marrow mesenchymal stem cells and stimulates angiogenesis by up-regulating the expression of vascular endothelial growth factor.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Materials Science, Biomaterials
Fan Wang, Ping Sun, En Xie, Yinjun Ji, Yunfei Niu, Fengqian Li, Jie Wei
Summary: This study developed an artificial ligament with osteogenic activity by coating polyetheretherketone fibers with a phytic acid/magnesium ion complex. The artificial ligament showed improved surface properties, slow release of magnesium ions, and enhanced responses of bone marrow stem cells and macrophages. The ligament also inhibited fibrous encapsulation and promoted osteogenesis in vivo. The results suggest that the coating of phytic acid/magnesium ion complex has tremendous potential for reconstructing the anterior cruciate ligament (ACL) by creating a pro-osteogenic and anti-inflammatory environment.
BIOMATERIALS ADVANCES
(2022)
Article
Chemistry, Multidisciplinary
Dan Yu, Yansong Liu, Yuanlin Ren, Xiaohui Liu, Hongqiang Qu
Summary: A facile and eco-friendly one-pot technique based on a safflower yellow derivative was used to give silk fabric dyeing, flame retardant, and UV-resistant performance. The modified silk samples showed improved color depth, flame retardancy, and excellent UV protection factor (UPF).
Article
Chemistry, Multidisciplinary
Xiaodong He, HuaJun Wu, Yan Wang, Yunjie Xiang, Kai Zhang, Xi Rao, En-Tang Kang, Liqun Xu
Summary: Surface modification is crucial for tailoring the functionalities of solid materials. In this study, a simple and universal surface modification method based on phytic acid (PA) is developed, which introduces antimicrobial function through the adhesion and electrostatic interaction of PA. The modified surfaces exhibit strong antibacterial performance due to the synergistic bactericidal effects of cationic polymers (CPs) and photothermal effect caused by Prussian blue nanoparticles (PB NPs). The PA-PB-CP coating disturbs the membrane integrity, enzymatic activity, and metabolism function of bacteria, leading to the elimination of adhered bacteria.
Article
Engineering, Environmental
Xiaodong He, Jieyu Zhang, Liwei Xie, Gnanasekar Sathishkumar, Chunmei Li, Xi Rao, Jing Zhao, Kai Zhang, Rui Wang, En-Tang Kang, Liqun Xu
Summary: This study investigated a simplified method for supramolecular assembly of natural bio compounds to develop functional coating layers. The coating exhibited antibacterial, anticorrosive, and biocompatible properties, and promoted endothelial cell proliferation. In addition, the coating demonstrated effective anti-fogging performance. The one-step co-deposition method provided a simple, environmentally benign, and sustainable approach for designing and fabricating multifunctional surfaces.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)