Should we develop screens for multi-drug antibiotic tolerance?

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

(2016) Valerie Defraine et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide

(2016) Mehmet A. Orman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Persistence and resistance as complementary bacterial adaptations to antibiotics

(2016) T. Vogwill et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells

(2016) Yingying Pu et al.   MOLECULAR CELL

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

(2016) Bram Van den Bergh et al.   Nature Microbiology

A Novel Point Mutation Promotes Growth Phase-Dependent Daptomycin Tolerance in Staphylococcus aureus

(2015) Lukas Mechler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combatting bacterial infections by killing persister cells with mitomycin C

(2015) Brian W. Kwan et al.   ENVIRONMENTAL MICROBIOLOGY

Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance

(2015) Natalie Verstraeten et al.   MOLECULAR CELL

Fitness trade-offs explain low levels of persister cells in the opportunistic pathogenPseudomonas aeruginosa

(2015) Kristine Stepanyan et al.   MOLECULAR ECOLOGY

HipBA–promoter structures reveal the basis of heritable multidrug tolerance

(2015) Maria A. Schumacher et al.   NATURE

Reversible Antibiotic Tolerance Induced in Staphylococcus aureus by Concurrent Drug Exposure

(2015) Jakob Haaber et al.   mBio

Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens

(2015) Leo Lin et al.   EBioMedicine

Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens

(2014) Lee W. Goneau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Mechanisms Underlying Bacterial Persisters

(2014) Etienne Maisonneuve et al.   CELL

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment

(2014) Patrick Kaiser et al.   PLOS BIOLOGY

A Screen for and Validation of Prodrug Antimicrobials

(2013) Laura E. Fleck et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microbial Persistence and the Road to Drug Resistance

(2013) Nadia R. Cohen et al.   Cell Host & Microbe

Activated ClpP kills persisters and eradicates a chronic biofilm infection

(2013) B. P. Conlon et al.   NATURE

High-Resolution Single Nucleotide Polymorphism Analysis Distinguishes Recrudescence and Reinfection in Recurrent Invasive Nontyphoidal Salmonella Typhimurium Disease

(2012) Chinyere K. Okoro et al.   CLINICAL INFECTIOUS DISEASES

Heterogeneous bacterial persisters and engineering approaches to eliminate them

(2011) Kyle R Allison et al.   CURRENT OPINION IN MICROBIOLOGY

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies

(2011) M. Fauvart et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis

(2010) L. R. Mulcahy et al.   JOURNAL OF BACTERIOLOGY