Pioglitazone for the treatment of Alzheimer’s disease

PPARγ agonist pioglitazone improves cerebellar dysfunction at pre-Aβ deposition stage in APPswe/PS1dE9 Alzheimer's disease model mice

(2016) Junya Toba et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinical drug research in chronic central neurodegenerative disorders

(2016) Thomas Müller et al.   Expert Review of Neurotherapeutics

Clinical drug research in chronic central neurodegenerative disorders

(2016) Thomas Müller et al.   Expert Review of Neurotherapeutics

Efficacy of memantine hydrochloride once-daily in Alzheimer’s disease

(2014) Alexander Kurz et al.   EXPERT OPINION ON PHARMACOTHERAPY

Transdermal rivastigmine in the treatment of Alzheimer’s disease: current and future directions

(2014) Hamid Reza Amanatkar et al.   Expert Review of Neurotherapeutics

Efficacy and safety of galantamine treatment for patients with Alzheimer’s disease: a meta-analysis of randomized controlled trials

(2014) Deqi Jiang et al.   JOURNAL OF NEURAL TRANSMISSION

TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial

(2013) Allen D. Roses et al.   Alzheimers & Dementia

Alzheimer disease therapy—moving from amyloid-β to tau

(2013) Ezio Giacobini et al.   Nature Reviews Neurology

PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid-  Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice

(2012) M. Yamanaka et al.   JOURNAL OF NEUROSCIENCE

Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

(2012) S. Mandrekar-Colucci et al.   JOURNAL OF NEUROSCIENCE

Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimers Disease: Two Phase 3 Studies

(2011) C. Harrington et al.   Current Alzheimer Research

The effect of rosiglitazone on LRP1 expression and amyloid β uptake in human brain microvascular endothelial cells: a possible role of a low-dose thiazolidinedione for dementia treatment

(2011) Jae Hoon Moon et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Progress in Alzheimer’s disease

(2011) Daniela Galimberti et al.   JOURNAL OF NEUROLOGY

Epidemiology of Alzheimer disease

(2011) Christiane Reitz et al.   Nature Reviews Neurology

A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients With Alzheimer Disease

(2010) David S. Geldmacher et al.   ARCHIVES OF NEUROLOGY

How does diabetes accelerate Alzheimer disease pathology?

(2010) Catrina Sims-Robinson et al.   Nature Reviews Neurology

APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure

(2009) Lynn M. Bekris et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats

(2008) G. J. Ko et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION