Pharmacodynamic considerations in the use of matrix metalloproteinase inhibitors in cancer treatment

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Phosphonate Emerging Zinc Binding Group in Matrix Metalloproteinase Inhibitors

(2015) Cristina Campestre et al.   CURRENT DRUG TARGETS

Current mechanistic insights into the roles of matrix metalloproteinases in tumour invasion and metastasis

(2015) Gordon T Brown et al.   JOURNAL OF PATHOLOGY

Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature

(2015) Elena I. Deryugina et al.   MATRIX BIOLOGY

New strategies for targeting matrix metalloproteinases

(2015) Gregg B. Fields   MATRIX BIOLOGY

Matrix remodeling by MMPs during wound repair

(2015) Maryam G. Rohani et al.   MATRIX BIOLOGY

Moving targets: Emerging roles for MMPs in cancer progression and metastasis

(2015) Gemma Shay et al.   MATRIX BIOLOGY

Matrix metalloproteinase inhibitors: a patent review (2011 – 2013)

(2014) Nian-Guang Li et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

High Level of Plasma Matrix Metalloproteinase-11 Is Associated with Clinicopathological Characteristics in Patients with Oral Squamous Cell Carcinoma

(2014) Chung-Han Hsin et al.   PLoS One

Matrix metalloproteinases and their tissue inhibitors in gastric cancer as molecular markers

(2013) ClaraL Sampieri et al.   Journal of Cancer Research and Therapeutics

Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid

(2012) P.G. Dedes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Matrix metalloproteinase-2 as a target for head and neck cancer therapy

(2012) Ming-Hsien Chien et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Role of lipocalin 2 and its complex with matrix metalloproteinase-9 in oral cancer

(2012) C-W Lin et al.   ORAL DISEASES

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression

(2011) Brigitte Bauvois   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Biological role of matrix metalloproteinases: a critical balance

(2010) S. Loffek et al.   EUROPEAN RESPIRATORY JOURNAL

Metalloproteinase binding proteins: WO2009097397

(2010) Yoshifumi Itoh   EXPERT OPINION ON THERAPEUTIC PATENTS

Role of Matrix Metalloproteinase-9 Dimers in Cell Migration

(2010) Antoine Dufour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models

(2009) Miriam Fanjul-Fernández et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structural and functional bases for allosteric control of MMP activities: Can it pave the path for selective inhibition?

(2009) Netta Sela-Passwell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Catalytic Domain Architecture of Metzincin Metalloproteases

(2009) F. Xavier Gomis-Rüth   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Hematin Interaction with the Hemopexin Domain of Gelatinase B/MMP-9 Provokes Autocatalytic Processing of the Propeptide, Thereby Priming Activation by MMP-3†

(2008) Nathalie Geurts et al.   BIOCHEMISTRY