- Home
- Publications
- Publication Search
- Publication Details
Title
Drug discovery beyond the rule of 5 - Opportunities and challenges
Authors
Keywords
-
Journal
Expert Opinion on Drug Discovery
Volume 12, Issue 2, Pages 115-119
Publisher
Informa UK Limited
Online
2016-11-24
DOI
10.1080/17460441.2017.1264385
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cell permeability beyond the rule of 5
- (2016) Pär Matsson et al. ADVANCED DRUG DELIVERY REVIEWS
- Small-Molecule PROTACS: New Approaches to Protein Degradation
- (2016) Momar Toure et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs
- (2016) Adrian Whitty et al. DRUG DISCOVERY TODAY
- How Beyond Rule of 5 Drugs and Clinical Candidates Bind to Their Targets
- (2015) Bradley C. Doak et al. JOURNAL OF MEDICINAL CHEMISTRY
- iPPI-DB: an online database of modulators of protein–protein interactions
- (2015) Céline M. Labbé et al. NUCLEIC ACIDS RESEARCH
- Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
- (2014) Michelle R. Arkin et al. CHEMISTRY & BIOLOGY
- Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
- (2014) Bradley Croy Doak et al. CHEMISTRY & BIOLOGY
- Conformational restriction: an effective tactic in 'follow-on'-based drug discovery
- (2014) Zengjun Fang et al. Future Medicinal Chemistry
- Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones
- (2014) Juan Pablo Maianti et al. NATURE
- How proteins bind macrocycles
- (2014) Elizabeth A Villar et al. Nature Chemical Biology
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Regulation of protein phosphatase 1 by intrinsically disordered proteins
- (2012) Meng S. Choy et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Structural Biology and Drug Discovery of Difficult Targets: The Limits of Ligandability
- (2012) Sachin Surade et al. CHEMISTRY & BIOLOGY
- Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa
- (2010) N. Srinivas et al. SCIENCE
- Design Strategies of Novel NNRTIs to Overcome Drug Resistance
- (2009) Peng Zhan et al. CURRENT MEDICINAL CHEMISTRY
- The exploration of macrocycles for drug discovery — an underexploited structural class
- (2008) Edward M. Driggers et al. NATURE REVIEWS DRUG DISCOVERY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now