The future of immunotherapy for sarcoma

CAR T Cell Therapy in Acute Lymphoblastic Leukemia and Potential for Chronic Lymphocytic Leukemia

(2016) Nathan Singh et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+Memory Stem Cells in Acquired Aplastic Anemia

(2016) Kohei Hosokawa et al.   JOURNAL OF IMMUNOLOGY

Prospects for gene-engineered T cell immunotherapy for solid cancers

(2016) Christopher A Klebanoff et al.   NATURE MEDICINE

Reconstruction After Tumor Resection in the Growing Child

(2016) John S. Groundland et al.   ORTHOPEDIC CLINICS OF NORTH AMERICA

Current status of treatment for pediatric rhabdomyosarcoma in the USA and Japan

(2016) Hajime Hosoi   PEDIATRICS INTERNATIONAL

Phase II study of ipilimumab monotherapy in Japanese patients with advanced melanoma

(2015) N. Yamazaki et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A phase I trial combining decitabine/dendritic cell vaccine targeting MAGE-A1, MAGE-A3 and NY-ESO-1 for children with relapsed or therapy-refractory neuroblastoma and sarcoma

(2015) Deepa K. Krishnadas et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Biologic Activity of Autologous, Granulocyte-Macrophage Colony-Stimulating Factor Secreting Alveolar Soft-Part Sarcoma and Clear Cell Sarcoma Vaccines

(2015) J. M. Goldberg et al.   CLINICAL CANCER RESEARCH

Polarization diversity of human CD4+ stem cell memory T cells

(2015) Masaru Takeshita et al.   CLINICAL IMMUNOLOGY

Immunotherapeutic Approaches to Sarcoma

(2015) Melissa Burgess et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

New toxicity profile for novel immunotherapy agents: focus on immune-checkpoint inhibitors

(2015) C Ciccarese et al.   Expert Opinion on Drug Metabolism & Toxicology

Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment

(2015) Sandra P. D’Angelo et al.   HUMAN PATHOLOGY

Osteosarcoma: Current Treatment and a Collaborative Pathway to Success

(2015) Michael S. Isakoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase 1 Study of Intratumoral Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus, in Pediatric Cancer Patients

(2015) Timothy P Cripe et al.   MOLECULAR THERAPY

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

Long-lasting stem cell–like memory CD8 + T cells with a naïve-like profile upon yellow fever vaccination

(2015) Silvia A. Fuertes Marraco et al.   Science Translational Medicine

Current Perspectives in Immunotherapy for Non-Small Cell Lung Cancer

(2015) Edward B. Garon   SEMINARS IN ONCOLOGY

Exome Sequencing to Predict Neoantigens in Melanoma

(2015) A. L. Pritchard et al.   Cancer Immunology Research

Plastic Surgery in the Multimodal Treatment Concept of Soft Tissue Sarcoma: Influence of Radiation, Chemotherapy, and Isolated Limb Perfusion on Plastic Surgery Techniques

(2015) Nicolai Kapalschinski et al.   Frontiers in Oncology

Secondary malignant neoplasms among children, adolescents, and young adults with osteosarcoma

(2014) Jean S. Lee et al.   CANCER

Finding suitable targets is the major obstacle to cancer gene therapy

(2014) Steven A Rosenberg   CANCER GENE THERAPY

A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response

(2014) P. F. Robbins et al.   CLINICAL CANCER RESEARCH

Serial Transfer of Single-Cell-Derived Immunocompetence Reveals Stemness of CD8+ Central Memory T Cells

(2014) Patricia Graef et al.   IMMUNITY

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

Programmed Cell Death Ligand 1 Expression in Osteosarcoma

(2014) J. K. Shen et al.   Cancer Immunology Research

Phase II study of personalized peptide vaccination for refractory bone and soft tissue sarcoma patients

(2013) Ryuji Takahashi et al.   CANCER SCIENCE

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

(2013) Richard A. Morgan et al.   JOURNAL OF IMMUNOTHERAPY

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

(2013) Paul F Robbins et al.   NATURE MEDICINE

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

High Expression of CD109 Antigen Regulates the Phenotype of Cancer Stem-Like Cells/Cancer-Initiating Cells in the Novel Epithelioid Sarcoma Cell Line ESX and Is Related to Poor Prognosis of Soft Tissue Sarcoma

(2013) Makoto Emori et al.   PLoS One

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

SYT-SSX breakpoint peptide vaccines in patients with synovial sarcoma: A study from the Japanese Musculoskeletal Oncology Group

(2012) Satoshi Kawaguchi et al.   CANCER SCIENCE

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

(2012) Hidekazu Kameshima et al.   CANCER SCIENCE

Lack of T-cell responses following autologous tumour lysate pulsed dendritic cell vaccination, in patients with relapsed osteosarcoma

(2012) Nourredine Himoudi et al.   Clinical & Translational Oncology

Sorting Through Subsets

(2012) Christopher A. Klebanoff et al.   JOURNAL OF IMMUNOTHERAPY

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeted Therapy in Bone and Soft Tissue Sarcoma in Children and Adolescents

(2012) Patrick A. Thompson et al.   Current Oncology Reports

Cytotoxic T lymphocytes: Sniping cancer stem cells

(2012) Yoshihiko Hirohashi et al.   OncoImmunology

Autologous CTL response against cancer stem-like cells/cancer-initiating cells of bone malignant fibrous histiocytoma

(2011) Masanobu Kano et al.   CANCER SCIENCE

Determinants of Successful CD8 + T-Cell Adoptive Immunotherapy for Large Established Tumors in Mice

(2011) Christopher A. Klebanoff et al.   CLINICAL CANCER RESEARCH

Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

(2011) Paul F. Robbins et al.   JOURNAL OF CLINICAL ONCOLOGY

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis

(2010) Maria R Parkhurst et al.   MOLECULAR THERAPY

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas

(2009) M Murase et al.   BRITISH JOURNAL OF CANCER

A Distinct Subset of Self-Renewing Human Memory CD8+ T Cells Survives Cytotoxic Chemotherapy

(2009) Cameron J. Turtle et al.   IMMUNITY

HLA-A*0201-restricted CTL epitope of a novel osteosarcoma antigen, papillomavirus binding factor

(2009) Tomohide Tsukahara et al.   Journal of Translational Medicine

Prognostic impact and immunogenicity of a novel osteosarcoma antigen, papillomavirus binding factor, in patients with osteosarcoma

(2008) Tomohide Tsukahara et al.   CANCER SCIENCE

A Pilot Study of Consolidative Immunotherapy in Patients with High-Risk Pediatric Sarcomas

(2008) C. L. Mackall et al.   CLINICAL CANCER RESEARCH

T-cell responses in osteosarcoma patients vaccinated with an anti-idiotypic antibody, 105AD7, mimicking CD55

(2008) G.J. Ullenhag et al.   CLINICAL IMMUNOLOGY

Osteosarcoma: The Addition of Muramyl Tripeptide to Chemotherapy Improves Overall Survival—A Report From the Children's Oncology Group

(2008) Paul A. Meyers et al.   JOURNAL OF CLINICAL ONCOLOGY

Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer

(2008) Tetsuhiro Tsuruma et al.   Journal of Translational Medicine

Clonal T-cell response against autologous pleomorphic malignant fibrous histiocytoma antigen presented by retrieved HLA-A*0206

(2007) Shigeharu Kimura et al.   JOURNAL OF ORTHOPAEDIC RESEARCH