Hypermethylation of BRCA1 gene: implication for prognostic biomarker and therapeutic target in sporadic primary triple-negative breast cancer

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Promoter methylation of BRCA1 in triple-negative breast cancer predicts sensitivity to adjuvant chemotherapy

(2013) Y. Xu et al.   ANNALS OF ONCOLOGY

BRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC

(2013) T. Ignatov et al.   BREAST CANCER RESEARCH AND TREATMENT

Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis

(2013) Liang Wu et al.   BREAST CANCER RESEARCH AND TREATMENT

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers

(2013) E H Lips et al.   BRITISH JOURNAL OF CANCER

BRCA1-methylated sporadic breast cancers are BRCA-like in showing a basal phenotype and absence of ER expression

(2012) Amanjit Bal et al.   VIRCHOWS ARCHIV

Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents

(2012) Nicolai J. Birkbak et al.   Cancer Discovery

BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype

(2011) Manuela Santarosa et al.   CANCER AND METASTASIS REVIEWS

Contribution of epigenetic alteration of BRCA1 and BRCA2 genes in breast carcinomas in Tunisian patients

(2011) R. Ben Gacem et al.   Cancer Epidemiology

CpG island hypermethylation ofBRCA1and loss of pRb as co-occurring events in basal/triple-negative breast cancer

(2011) Olafur Andri Stefansson et al.   Epigenetics

Epigenetic silencing of BRCA1 gene associated with demographic and pathologic factors in sporadic breast cancer

(2011) Alok Kumar Singh et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese

(2011) Da Pang et al.   MEDICAL ONCOLOGY

Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors

(2010) Simon A. Joosse et al.   GENES CHROMOSOMES & CANCER

Therapeutic Potential of Poly(ADP-ribose) Polymerase Inhibitor AG014699 in Human Cancers With Mutated or Methylated BRCA1 or BRCA2

(2010) Yvette Drew et al.   JNCI-Journal of the National Cancer Institute

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

(2010) Fiona M. Blows et al.   PLOS MEDICINE

Sensitivity to First-Line Chemotherapy for Metastatic Breast Cancer inBRCA1andBRCA2Mutation Carriers

(2009) Mieke Kriege et al.   JOURNAL OF CLINICAL ONCOLOGY

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

BRCA1 promoter methylation is associated with increased mortality among women with breast cancer

(2008) Xinran Xu et al.   BREAST CANCER RESEARCH AND TREATMENT