Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy

SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

(2021) Jianwei Chen et al.   Aging-US

Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of Sirtuin 1

(2021) Lili Zhang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

NFATc4 mediates ethanol-triggered hepatocyte senescence

(2021) Ruoman Wu et al.   TOXICOLOGY LETTERS

Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles

(2020) Ren-Qi Yao et al.   Autophagy

Pterostilbene as a protective antioxidant attenuates diquat-induced liver injury and oxidative stress in 21-day-old broiler chickens

(2020) Yanan Chen et al.   POULTRY SCIENCE

Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition

(2020) Ying-Jan Wang et al.   Frontiers in Cell and Developmental Biology

Inhibition of cellular communication network factor 1 (CCN1)-driven senescence slows down cartilage inflammaging and osteoarthritis

(2020) Meng Feng et al.   BONE

Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis

(2020) Renchao Dong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pterostilbene Exerts Hepatoprotective Effects through Ameliorating LPS/D-Gal-Induced Acute Liver Injury in Mice

(2020) Ziyi Liu et al.   INFLAMMATION

Pterostilbene attenuates liver injury and oxidative stress in intrauterine growth–retarded weanling piglets

(2020) Hao Zhang et al.   NUTRITION

Cobalt oxide nanoparticle-synergized protein degradation and phototherapy for enhanced anticancer therapeutics

(2020) Xueqin Huang et al.   Acta Biomaterialia

Identifying CYR 61 as a Potential Anti‐fibrotic and Pro‐angiogenic Mediator in Scleroderma

(2019) Pei‐Suen Tsou et al.   Arthritis & Rheumatology

Dysregulated autophagy and lysosome function are linked to exosome production via miR‐155 in alcoholic liver disease

(2019) Mrigya Babuta et al.   HEPATOLOGY

Inhibition of eIF2α dephosphorylation accelerates pterostilbene-induced cell death in human hepatocellular carcinoma cells in an ER stress and autophagy-dependent manner

(2019) Chen-Lin Yu et al.   Cell Death & Disease

CCN1-Induced Cellular Senescence Promotes Heart Regeneration

(2019) Teng Feng et al.   CIRCULATION

The role of senescence in the development of non-alcoholic fatty liver disease and progression to non-alcoholic steatohepatitis

(2019) Alkistis-Maria Papatheodoridi et al.   HEPATOLOGY

Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism

(2019) Ying Zhou et al.   TOXICOLOGY IN VITRO

SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence

(2019) Gloria Salazar et al.   Autophagy

Effects of pterostilbene on diabetes, liver steatosis and serum lipids

(2019) Saioa Gómez-Zorita et al.   CURRENT MEDICINAL CHEMISTRY

Oroxylin A inhibits ethanol-induced hepatocyte senescence via  YAP pathway

(2018) Huanhuan Jin et al.   CELL PROLIFERATION

Pterostilbene protects against acetaminophen-induced liver injury by restoring impaired autophagic flux

(2018) Ki-Young Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Mitochondria and cellular senescence: Implications for musculoskeletal ageing

(2018) Leena Habiballa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pterostilbene alleviates polymicrobial sepsis-induced liver injury: Possible role of SIRT1 signaling

(2017) Xiaojing Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Nrf2 induces lipocyte phenotype via a SOCS3-dependent negative feedback loop on JAK2/STAT3 signaling in hepatic stellate cells

(2017) Chunfeng Lu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence

(2016) Haoran Tai et al.   Autophagy

Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis

(2016) Chunfeng Lu et al.   MOLECULAR PHARMACEUTICS

Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes

(2016) Chunfeng Lu et al.   TOXICOLOGICAL SCIENCES

Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation

(2016) Chunfeng Lu et al.   TOXICOLOGY

The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions

(2015) RM Gorojod et al.   FREE RADICAL BIOLOGY AND MEDICINE

A method to measure cardiac autophagic flux in vivo

(2014) Eri Iwai-Kanai et al.   Autophagy

Hedgehog signaling pathway regulates autophagy in human hepatocellular carcinoma cells

(2013) Ying Wang et al.   HEPATOLOGY

CCN1 expression in hepatocytes contributes to macrophage infiltration in nonalcoholic fatty liver disease in mice

(2012) Zhaolian Bian et al.   JOURNAL OF LIPID RESEARCH

The emerging role of autophagy in alcoholic liver disease

(2011) Wen-Xing Ding et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY