Polyamine: A metabolic compass for T helper cell fate direction

In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

(2021) Hongling Huang et al.   CELL

Metabolic modeling of single Th17 cells reveals regulators of autoimmunity

(2021) Allon Wagner et al.   CELL

Polyamine metabolism is a central determinant of helper T cell lineage fidelity

(2021) Daniel J. Puleston et al.   CELL

Regulating T cell differentiation through the polyamine spermidine

(2020) Guilhermina M. Carriche et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

(2020) Lin Wu et al.   CELL

De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function

(2020) Ruohan Wu et al.   Science Advances

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

(2019) Daniel J. Puleston et al.   Cell Metabolism

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

(2018) Peer W. F. Karmaus et al.   NATURE

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

(2015) Chao Wang et al.   CELL

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY