Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein‐Barr virus–positive gastric cancer

Epstein‐Barr virus positive gastric cancer involves enhancer activation through ATF3

(2020) Yuta Asakawa et al.   CANCER SCIENCE

Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences

(2020) Sushant Kumar et al.   CELL

Gastric cancer: genome damaged by bugs

(2020) Yanan Zhao et al.   ONCOGENE

EHF promotes colorectal carcinoma progression by activating TGF‐β1 transcription and canonical TGF‐β signalling

(2020) Lan Wang et al.   CANCER SCIENCE

Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance

(2020) Li Yuan et al.   Molecular Cancer

Cross-species chromatin interactions drive transcriptional rewiring in Epstein–Barr virus–positive gastric adenocarcinoma

(2020) Atsushi Okabe et al.   NATURE GENETICS

Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma

(2019) Jing Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Epstein-Barr virus infection induces genome-wide de novo DNA methylation in non-neoplastic gastric epithelial cells

(2017) Keisuke Matsusaka et al.   JOURNAL OF PATHOLOGY

Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus

(2017) Atsushi Okabe et al.   Scientific Reports

Pathobiology of Helicobacter pylori–Induced Gastric Cancer

(2016) Manuel Amieva et al.   GASTROENTEROLOGY

Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

(2016) Zachary Steinhart et al.   NATURE MEDICINE

Increased expression of EHF via gene amplification contributes to the activation of HER family signaling and associates with poor survival in gastric cancer

(2016) Jing Shi et al.   Cell Death & Disease

The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

(2016) Domenico Albino et al.   Oncotarget

TET2 functions as a resistance factor against DNA methylation acquisition during Epstein-Barr virus infection

(2016) Hiroe Namba-Fukuyo et al.   Oncotarget

Knockdown of EHF inhibited the proliferation, invasion and tumorigenesis of ovarian cancer cells

(2015) Zhongping Cheng et al.   MOLECULAR CARCINOGENESIS

Enhancer Malfunction in Cancer

(2014) Hans-Martin Herz et al.   MOLECULAR CELL

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Classification of Epstein-Barr Virus-Positive Gastric Cancers by Definition of DNA Methylation Epigenotypes

(2011) K. Matsusaka et al.   CANCER RESEARCH

EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1

(2011) Helene Geddert et al.   CELLULAR ONCOLOGY

Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric Carcinoma

(2009) R. Hino et al.   CANCER RESEARCH

Meta-analysis Shows That Prevalence of Epstein–Barr Virus-Positive Gastric Cancer Differs Based on Sex and Anatomic Location

(2009) Gwen Murphy et al.   GASTROENTEROLOGY

Epstein-Barr virus and gastric carcinoma: virus-host interactions leading to carcinoma

(2008) Masashi Fukayama et al.   CANCER SCIENCE