Review
Oncology
Gang Li, Hongxiang Ji, Jiang Li, Linfeng Xiao, Zhan Chen
Summary: This meta-analysis found that mastectomy with immediate reconstruction does not affect postoperative survival rates in breast cancer patients who have completed neoadjuvant chemotherapy. However, it may slightly increase the risk of short-term surgical complications.
FRONTIERS IN ONCOLOGY
(2023)
Review
Surgery
Rachel Xue Ning Lee, Maria Joao Cardoso, Kwok-Leung Cheung, Ruth M. Parks
Summary: The uptake of postmastectomy immediate breast reconstruction (PMIBR) in older women is significantly lower than in younger women, and there are definable (and some correctable) barriers to this trend.
BRITISH JOURNAL OF SURGERY
(2022)
Article
Health Care Sciences & Services
Lorenzo Scardina, Alba Di Leone, Ersilia Biondi, Beatrice Carnassale, Alejandro Martin Sanchez, Sabatino D'Archi, Antonio Franco, Francesca Moschella, Stefano Magno, Daniela Terribile, Damiano Gentile, Alessandra Fabi, Anna D'Angelo, Liliana Barone Adesi, Giuseppe Visconti, Marzia Salgarello, Riccardo Masetti, Gianluca Franceschini
Summary: This study compared the outcomes of submuscular versus prepectoral implant placement in conservative mastectomy with immediate prosthetic breast reconstruction. The results showed that prepectoral implant placement is a safe and effective alternative with shorter operative time and fewer complications related to manipulation of the pectoralis major muscle.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Surgery
Ajla Sabitovic, Hannah Trostrup, Tine Engberg Damsgaard
Summary: This study conducted a meta-analysis of previously published studies and found that neoadjuvant chemotherapy (NACT) does not significantly impact the complication rate after breast reconstruction in breast cancer patients. In terms of minor complications, single-stage direct-to-implant (DTI) appears to be a safer procedure than two-staged tissue expander/implant (TE/I).
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2023)
Review
Oncology
Claudia A. Bargon, Danny A. Young-Afat, Mehmet Ikinci, Assa Braakenburg, Hinne A. Rakhorst, Marc A. M. Mureau, Helena M. Verkooijen, Annemiek Doeksen
Summary: The oncological safety of different types and timings of postmastectomy breast reconstruction (PMBR) remains controversial. This study found that delayed autologous PMBR leads to similar (loco)regional recurrence rates as immediate autologous PMBR. Current evidence suggests that oncological concerns should not be a reason to withhold patients from certain reconstructive timings or techniques, and patients should be offered all technically qualified reconstructive options equally.
Review
Oncology
Komla Sena Amouzou, Ameyo Ayoko Ketevi, Damigou Mawuli Sambiani, Angela Caroli
Summary: This study assessed the current modalities of female breast cancer surgeries in sub-Saharan countries, highlighting the need for structured management through shared guidelines, protocols, and specific public health programs. The findings suggest a focus on decreasing radical mastectomy and increasing breast-conserving surgeries.
JOURNAL OF SURGICAL ONCOLOGY
(2022)
Review
Surgery
Remy Liechti, Bryan J. M. van de Wall, Urs Hug, Elmar Fritsche, Alberto Franchi
Summary: This study found that the perioperative use of TXA significantly reduces the risk of postoperative hematoma and seroma formation in breast surgery, without increasing the risk of thromboembolic events and postoperative infection.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Review
Oncology
Kadhim Taqi, Jin-Si Pao, Leo Chen, Crystal Ma, Mabel Zhang, Elaine McKevitt, Amy Bazzarelli, Carol Dingee, Rebecca Warburton
Summary: Immediate breast reconstruction (IBR) following mastectomy is a safe option for patients with locally advanced breast cancer, with higher overall survival compared to mastectomy alone. However, it does not have significant impact on disease-specific survival, disease-free survival, local recurrence, adjuvant therapy use, or reoperation rates.
BREAST CANCER RESEARCH AND TREATMENT
(2021)
Article
Surgery
Hong Bae Jeon, Ji Hyuk Jung, Sang Hee Im, Yong Bae Kim, Jee Suk Chang, Seung Yong Song, Dae Hyun Lew, Tai Suk Roh, Won Jai Lee, Dong Won Lee
Summary: This study aimed to investigate the impact of immediate breast reconstruction on the risk of breast cancer-related lymphedema. The results showed that immediate breast reconstruction can reduce the incidence of lymphedema.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Oncology
Zhen-Yu Wu, Hee Jeong Kim, Jong Won Lee, Il Yong Chung, Jisun Kim, Sae Byul Lee, Byung-Ho Son, Jin Sup Eom, Jae Ho Jeong, Gyungyub Gong, Hak Hee Kim, Sei-Hyun Ahn, BeomSeok Ko
Summary: This study evaluated the factors predicting locoregional recurrence (LRR) in breast cancer patients who underwent neoadjuvant chemotherapy (NACT) and immediate breast reconstruction (IBR). Patients with post-NACT Ki67 >= 10%, high tumor grade, and presence of lymphovascular invasion (LVI) were found to have an increased risk of developing LRR. High LRR rates were observed in patients with all three associated risk factors compared to those with none or fewer factors.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Basilio Duenas-Rodriguez, Joaquin Navarro-Cecilia, Carolina Luque-Lopez, Belen Sanchez-Andujar, Juan Arsenio Garcelan-Trigo, Maria Jesus Ramirez-Exposito, Jose Manuel Martinez-Martos
Summary: This study evaluated postoperative complications, aesthetic results, and satisfaction outcomes in patients with breast cancer who underwent skin-sparing or nipple-sparing mastectomy with immediate prosthetic reconstruction. The use of a biological mesh during reconstruction resulted in lower implant loss and higher satisfaction rates.
Review
Dermatology
Julia A. Cook, Mithun Sinha, Mary Lester, Carla S. Fisher, Chandan K. Sen, Aladdin H. Hassanein
Summary: This article introduces the definition and impact of lymphedema, and proposes a treatment method called ILR, which can reduce the risk of lymphedema through prophylactic lymphovenous anastomosis. Lymphedema has significant effects on the quality of life and morbidity of patients, and ILR may be an effective prophylactic treatment method. Long-term studies are needed in the future to demonstrate the efficacy of ILR.
ADVANCES IN WOUND CARE
(2022)
Article
Oncology
Alessandro Fancellu, Giulia Deiana, Valeria Sanna, Corrado Rubino, Antonio Cossu, Pietrina Cottu, Giuliana Giuliani, Lisa Sant, Giuseppe Norcia, Alberto Porcu
Summary: The use of immediate breast reconstruction (IBR) after mastectomy has been increasing in all age groups. This study evaluated the age-specific trend of IBR and its impact on work organization at an Italian Breast Unit. The results showed that rates of mastectomy + IBR increased over the years, especially among older women. Furthermore, mastectomy + IBR resulted in longer operative times and hospital stay compared to mastectomy alone.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Review
Oncology
Seok Kyung Kang, Dong Il Kim, Seungju Lee, Youn Joo Jung, Jung Yeol Seo, Su Bong Nam, Kyoungjune Pak, Seokwon Lee, Hyun Yul Kim
Summary: A systematic review and meta-analysis of breast reconstruction after mastectomy showed similar event-free survival (EFS) and breast cancer-specific survival (BCSS) rates compared to mastectomy alone, but better overall survival (OS). Breast reconstruction is a feasible and safe treatment option for breast cancer patients.
TRANSLATIONAL CANCER RESEARCH
(2023)
Article
Surgery
Marloes E. Clarijs, Noelle J. M. C. Vrancken Peeters, Sophie A. F. van Dongen, Linetta B. Koppert, Andrea L. Pusic, Marc A. M. Mureau, Bianca F. M. Rijken
Summary: This systematic review compared patient-reported outcomes (PROs) and complication rates after nipple-sparing mastectomy (NSM) and skin-sparing mastectomy (SSM). The study found that NSM resulted in higher scores in sexual and psychosocial well-being, with no differences in overall complication rates between the two groups. Therefore, the decision for NSM or SSM should be made on an individual basis, considering factors such as patient preferences and safety.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Review
Surgery
Pathik Aravind, Salih Colakoglu, Myan Bhoopalam, Ahmed Ibrahim, David Mathes, Christodoulos Kaoutzanis, Marc Mureau, Sashank Reddy
Summary: This study systematically reviewed the characteristics of perforators in deep inferior epigastric perforator (DIEP) flap breast reconstruction and found that a single dominant perforator and medial row perforators may be associated with a higher risk of fat necrosis. Adopting a standardized perforator selection algorithm could help surgeons make operative decisions and improve postoperative outcomes.
JOURNAL OF RECONSTRUCTIVE MICROSURGERY
(2023)
Article
Surgery
L. L. Bruin, C. A. Hundepool, L. S. Duraku, A. J. M. Luijsterburg, T. De Jong, W. F. Willems, M. A. M. Mureau, J. M. Zuidam
Summary: This study aimed to investigate the incidence, prognostic factors, and impact on quality of life of neuropathic pain following radial forearm free flap (RFFF) harvest. The results showed that neuropathic pain was significantly correlated with poorer hand function and a poorer quality of life.
JOURNAL OF RECONSTRUCTIVE MICROSURGERY
(2023)
Article
Oncology
Anouk H. Eijkelboom, Linda de Munck, C. Willemien Menke-van der Houven Van Oordt, Mireille J. M. Broeders, Desiree H. J. G. van den Bongard, Luc J. A. Strobbe, Marc A. M. Mureau, Marc B. Lobbes, Pieter J. Westenend, Linetta B. Koppert, Agnes Jager, Ester J. M. Siemerink, Jelle Wesseling, Helena M. Verkooijen, Marie-Jeanne T. F. D. Vrancken Peeters, Marjolein L. Smidt, Vivianne C. G. Tjan-Heijnen, Sabine Siesling
Summary: This study compared the treatments and time intervals between treatments of breast cancer patients diagnosed during and before the COVID-19 pandemic, and the number of treatments started during and before the pandemic. The results showed that patients diagnosed during the transition period were less likely to receive neo-adjuvant chemotherapy for stage I, stage II, and hormone receptor+/HER2- tumors compared to 2018/2019. The time between diagnosis and first treatment decreased for patients diagnosed during the lockdown period. Additionally, there was an increase in the number of neo-adjuvant endocrine therapies and surgeries starting in week 14 of 2020, while the number of adjuvant chemotherapies decreased in week 15 and increased in week 22.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Surgery
Babette E. Becherer, Ingrid Hopper, Rodney D. Cooter, Benoit Couturaud, Uwe von Fritschen, Erin Mullen, A. Graeme B. Perks, Andrea L. Pusic, Birgit Stark, Marc A. M. Mureau, Hinne A. Rakhorst
Summary: For the first time, independent, national, registry-based data from four breast implant registries were combined, which is a powerful step forward in optimizing international breast implant monitoring, evidence-based decision-making, and patient safety.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Surgery
Babette E. Becherer, Erik A. Heeg, Danny A. Young-Afat, Marie-Jeanne T. F. D. Vrancken Peeters, Hinne A. Rakhorst, Marc A. M. Mureau
Summary: In this population-based study in the Netherlands, the incidence of unplanned revision surgery was lower in immediate implant-based breast reconstruction using a direct-to-implant approach compared to a two-stage approach. Additionally, more breasts were reconstructed within the planned number of operations in the direct-to-implant group.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Surgery
Marloes E. Clarijs, Noelle J. M. C. Vrancken Peeters, Sophie A. F. van Dongen, Linetta B. Koppert, Andrea L. Pusic, Marc A. M. Mureau, Bianca F. M. Rijken
Summary: This systematic review compared patient-reported outcomes (PROs) and complication rates after nipple-sparing mastectomy (NSM) and skin-sparing mastectomy (SSM). The study found that NSM resulted in higher scores in sexual and psychosocial well-being, with no differences in overall complication rates between the two groups. Therefore, the decision for NSM or SSM should be made on an individual basis, considering factors such as patient preferences and safety.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Public, Environmental & Occupational Health
Jonathan Spoor, Marc A. M. Mureau, Juliette Hommes, Hinne Rakhorst, Anneriet E. Dassen, Hester S. A. Oldenburg, Yvonne L. J. Vissers, Esther M. Heuts, Linetta B. Koppert, Laura H. Zaal, Rene R. W. J. van der Hulst, Marie-Jeanne T. F. D. Vrancken Peeters, Eveline M. A. Bleiker, Flora E. van Leeuwen
Summary: This article introduces the Areola study, which aims to assess the risks of breast implant illness (BII) and autoimmune diseases in Dutch breast cancer survivors with silicone breast implants. The study design includes a retrospective cohort of breast cancer survivors who underwent implant-based reconstruction surgery between 2000 and 2015 in six major hospitals in the Netherlands. A comparison group of breast cancer survivors without breast implants and a group of women who received breast augmentation surgery will also be included. The study will collect data through a web-based questionnaire and link it with population-based databases to evaluate the prevalence, incidence, and risk factors of BII and autoimmune disorders.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Surgery
Yara Lynn Blok, Jaco Suijker, Monique P. van den Tol, Carmen C. van der Pol, Marc A. M. Mureau, Jos A. van der Hage, Nicole M. A. Krekel
Summary: This study investigated the techniques and opinions of Dutch plastic surgeons and oncological breast surgeons regarding the preservation of pectoral fascia (PF) during mastectomy. The results showed that approximately one in five plastic surgeons and breast surgeons routinely preserve the PF, and even more surgeons preserve the PF in specific cases. There were significant differences in surgical techniques and opinions regarding PF preservation among the surgeons. Future studies should clarify the impact of PF preservation on oncological safety, complication rates, postoperative pain, cosmetic outcomes, and patient satisfaction.
JOURNAL OF SURGICAL RESEARCH
(2023)
Article
Surgery
J. Xavier Harmeling, Leonie A. E. Woerdeman, Ezgi Ozdemir, Michael Schaapveld, Hester S. A. Oldenburg, Cecile P. M. Janus, Nicola S. Russell, Linetta B. Koppert, Inge M. Krul, Flora E. van Leeuwen, Marc A. M. Mureau
Summary: There is no increased risk of adverse outcomes for breast reconstruction after previous chest radiotherapy for Hodgkin lymphoma (HL). These findings are important for counseling patients and making shared decisions about breast reconstruction.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Public, Environmental & Occupational Health
Sri K. Devarakonda, Reinier Timman, Paul F. Bouvy, Arvind Oemrawsingh, Inge Apon, Marc A. M. Mureau, Linetta B. Koppert, Leonieke W. Kranenburg
Summary: This study aimed to explore the trends in emotional functioning and psychosocial wellbeing of breast cancer survivors, as well as the demographic and treatment characteristics that may influence these trends. The findings showed a decline in psychosocial wellbeing and a steady improvement in emotional functioning over time. Women who underwent breast reconstruction experienced a more significant improvement in emotional functioning, while women with no partner or children showed a marginal decline in psychosocial wellbeing.
Article
Medicine, Research & Experimental
F. P. Tange, P. S. Verduijn, B. G. Sibinga Mulder, L. van Capelle, S. Koning, C. Driessen, M. A. M. Mureau, A. L. Vahrmeijer, J. R. van der Vorst
Summary: This study aims to reduce the occurrence of fat necrosis by using ICG-NIR-FA technology to evaluate the perfusion of DIEP flaps. A total of 280 females undergoing autologous breast reconstruction with DIEP or msTRAM flaps will be randomly assigned to the intervention or control group. The main endpoint of the study is the difference in clinically relevant fat necrosis between the two groups evaluated at two weeks and three months after reconstruction.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2023)
Article
Oncology
Dave T. Hamersma, Kay Schreuder, Gijs Geleijnse, Erik Heeg, Matteo Cellamare, Marc B. I. Lobbes, Marc A. M. Mureau, Linetta B. Koppert, Helle Skjerven, Jan F. Nygard, Catharina G. M. Groothuis-Oudshoorn, Sabine Siesling
Summary: The aim of this study was to compare breast cancer care quality indicators (QIs) between Norway and the Netherlands using federated analytics. Data from breast cancer patients in both countries were retrieved and assessed using European Society of Breast Cancer Specialists (EUSOMA) QIs. The study found that both countries scored high on the QIs, but differences were observed in the use of MRI and proportion of patients receiving single surgery.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Dentistry, Oral Surgery & Medicine
Kira S. van Hof, Marlies Wakkee, Aniel Sewnaik, Aimee F. Herkendaal, Lisa Tans, Hetty Mast, Renate R. van den Bos, Marc A. M. Mureau, Marinella P. J. Offerman, Robert J. Baatenburg de Jong
Summary: The purpose of this retrospective study was to describe the medical outcomes, patient-reported outcomes, and costs of different treatments for early stage lip SCC. The study findings showed that Mohs micrographic surgery (MMS) had the best outcomes and lowest costs among the treatments evaluated.
Article
Health Care Sciences & Services
N. J. M. C. Vrancken Peeters, Z. L. R. Kaplan, M. E. Clarijs, M. A. M. Mureau, C. Verhoef, T. van Dalen, O. Husson, L. B. Koppert
Summary: This study examined the long-term effects of axillary treatments on health-related quality of life in breast cancer patients. Except for axillary lymph node dissection (ALND) with axillary radiotherapy, other axillary treatments showed no significant impact on physical and psychosocial wellbeing. Patients who received ALND with radiotherapy experienced a significant decrease in physical and psychosocial wellbeing postoperatively.
QUALITY OF LIFE RESEARCH
(2023)
Article
Surgery
E. R. Eijsink, J. X. Harmeling, M. A. M. Mureau, E. M. L. Corten
Summary: This study examined the factors influencing plastic surgeons' choice of breast implants and found substantial variation in the weighing of these factors among different surgeons. It also revealed that the choice of breast implants is not solely based on scientific evidence, but brand reputation plays a significant role. Therefore, it is crucial for patients to have comprehensive knowledge about all aspects of breast implants during shared decision making.
