Aurora kinase A and B as new treatment targets in aromatase inhibitor-resistant breast cancer cells

New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane

(2015) STINE HOLE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer

(2015) Shuying Liu et al.   Oncotarget

Estrogen receptor α is the major driving factor for growth in tamoxifen-resistant breast cancer and supported by HER/ERK signaling

(2013) Susan Thrane et al.   BREAST CANCER RESEARCH AND TREATMENT

Aromatase inhibition 2013: clinical state of the art and questions that remain to be solved

(2013) Per Eystein Lønning et al.   ENDOCRINE-RELATED CANCER

The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer

(2012) Julia A Beaver et al.   Future Oncology

Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays

(2011) M. G. Manfredi et al.   CLINICAL CANCER RESEARCH

Aromatase, aromatase inhibitors, and breast cancer

(2011) Saranya Chumsri et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

ER -Dependent E2F Transcription Can Mediate Resistance to Estrogen Deprivation in Human Breast Cancer

(2011) T. W. Miller et al.   Cancer Discovery

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer

(2010) Christopher P Gully et al.   Molecular Cancer

Aurora Kinase Inhibitors - Rising Stars in Cancer Therapeutics?

(2010) A. A. Dar et al.   MOLECULAR CANCER THERAPEUTICS

Aurora B Kinase Regulates the Postmitotic Endoreduplication Checkpoint via Phosphorylation of the Retinoblastoma Protein at Serine 780

(2009) Jayasree S. Nair et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for androgen specificity and oestrogen synthesis in human aromatase

(2009) Debashis Ghosh et al.   NATURE

Genome-Wide Analysis of Aromatase Inhibitor-Resistant, Tamoxifen-Resistant, and Long-Term Estrogen-Deprived Cells Reveals a Role for Estrogen Receptor

(2008) S. Masri et al.   CANCER RESEARCH

The regulatory β-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis

(2008) C W Yde et al.   ONCOGENE