Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice

Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

(2020) F. Kyle Satterstrom et al.   CELL

The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin

(2020) Hang Gyeong Chin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genotype–phenotype correlation at codon 1740 of SETD2

(2020) Rachel Rabin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

(2020) Riyad N. H. Seervai et al.   Science Advances

SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

(2019) Alessandro Sessa et al.   NEURON

SETD2 related overgrowth syndrome: Presentation of four new patients and review of the literature

(2019) Pauline Marzin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

(2019) Aviel Even et al.   Science Advances

Two novel cases expanding the phenotype of SETD2 -related overgrowth syndrome

(2018) Maartje C. van Rij et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

SETD2 Haploinsufficiency for Microtubule Methylation is an Early Driver of Genomic Instability in Renal Cell Carcinoma

(2018) Yun Chen Chiang et al.   CANCER RESEARCH

Chromatin in nervous system development and disease

(2018) Shigeki Iwase et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition

(2018) Elena Deliu et al.   NATURE NEUROSCIENCE

Anxiety Disorders and Obsessive-Compulsive Disorder in Individuals with Autism Spectrum Disorder

(2017) Valentina Postorino et al.   Current Psychiatry Reports

Chromatin Remodeling BAF (SWI/SNF) Complexes in Neural Development and Disorders

(2017) Godwin Sokpor et al.   Frontiers in Molecular Neuroscience

Dual Chromatin and Cytoskeletal Remodeling by SETD2

(2016) In Young Park et al.   CELL

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase

(2016) Shuang Yang et al.   GENES & DEVELOPMENT

Methylated α-tubulin antibodies recognize a new microtubule modification on mitotic microtubules

(2016) In Young Park et al.   mAbs

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms

(2015) Alissa M. D’Gama et al.   NEURON

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

(2015) Stephan J. Sanders et al.   NEURON

Mutations inSETD2cause a novel overgrowth condition

(2014) Armelle Luscan et al.   JOURNAL OF MEDICAL GENETICS

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects

(2013) J. M. Simon et al.   GENOME RESEARCH

From neural development to cognition: unexpected roles for chromatin

(2013) Jehnna L. Ronan et al.   NATURE REVIEWS GENETICS

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

(2012) Rodney C Samaco et al.   NATURE GENETICS

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

MEC-17 is an α-tubulin acetyltransferase

(2010) Jyothi S. Akella et al.   NATURE

Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling

(2010) M. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The major  -tubulin K40 acetyltransferase  TAT1 promotes rapid ciliogenesis and efficient mechanosensation

(2010) T. Shida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A partial loss of function allele of Methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

(2008) R. C. Samaco et al.   HUMAN MOLECULAR GENETICS

NeuriteTracer: A novel ImageJ plugin for automated quantification of neurite outgrowth

(2007) Madeline Pool et al.   JOURNAL OF NEUROSCIENCE METHODS