Visualisation of tumour cells in bone in vivo at single-cell resolution

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

(2021) Michelle M. McDonald et al.   CELL

In vivo dynamic analysis of BMP-2-induced ectopic bone formation

(2020) Kunihiko Hashimoto et al.   Scientific Reports

A Niche-Dependent Myeloid Transcriptome Signature Defines Dormant Myeloma Cells

(2019) Weng Hua Khoo et al.   BLOOD

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

(2019) Ninib Baryawno et al.   CELL

The bone marrow microenvironment at single-cell resolution

(2019) Anastasia N. Tikhonova et al.   NATURE

The Unmixing Problem: A Guide to Applying Single-Cell RNA Sequencing to Bone

(2019) Matthew B Greenblatt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths

(2019) Samuel L. Wolock et al.   Cell Reports

The bone metastasis niche in breast cancer: potential overlap with the haematopoietic stem cell niche in vivo

(2019) Gloria Allocca et al.   Journal of Bone Oncology

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization

(2019) Chiara Baccin et al.   NATURE CELL BIOLOGY

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

(2018) Delfim Duarte et al.   Cell Stem Cell

Direct cell–cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo

(2018) Masayuki Furuya et al.   Nature Communications

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone

(2018) Eleonora Dondossola et al.   Science Translational Medicine

Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear-cytoplasmic labeling

(2017) Soyeon Ahn et al.   PLoS One

Severe rebound-associated vertebral fractures after denosumab discontinuation: nine clinical cases report

(2016) Olivier Lamy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

(2016) Edwin D. Hawkins et al.   NATURE

Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche

(2015) Diego Correa et al.   INTERNATIONAL JOURNAL OF CANCER

Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair

(2015) Chunlan Huang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Severe spontaneous vertebral fractures after denosumab discontinuation: three case reports

(2015) B. Aubry-Rozier et al.   OSTEOPOROSIS INTERNATIONAL

Rebound-associated vertebral fractures after discontinuation of denosumab—from clinic and biomechanics

(2015) A. W. Popp et al.   OSTEOPOROSIS INTERNATIONAL

Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche

(2015) Michelle A. Lawson et al.   Nature Communications

Modifying the osteoblastic niche with zoledronic acid in vivo—Potential implications for breast cancer bone metastasis

(2014) Marie-Therese Haider et al.   BONE

Zoledronic Acid Has Differential Antitumor Activity in the Pre- and Postmenopausal Bone Microenvironment In Vivo

(2014) P. D. Ottewell et al.   CLINICAL CANCER RESEARCH

Castration-induced bone loss triggers growth of disseminated prostate cancer cells in bone

(2014) P. D. Ottewell et al.   ENDOCRINE-RELATED CANCER

Prostate Cancer Cells Preferentially Home to Osteoblast-rich Areas in the Early Stages of Bone Metastasis: Evidence From In Vivo Models

(2014) Ning Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Visualizing Osteogenesis In Vivo Within a Cell–Scaffold Construct for Bone Tissue Engineering Using Two-Photon Microscopy

(2013) Max M. Villa et al.   TISSUE ENGINEERING PART C-METHODS

Quantitative second-harmonic generation microscopy for imaging porcine cortical bone: Comparison to SEM and its potential to investigate age-related changes

(2011) Raghu Ambekar et al.   BONE

Intravital Imaging

(2011) Mikael J. Pittet et al.   CELL

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study

(2011) Karim Fizazi et al.   LANCET

Denosumab Compared With Zoledronic Acid for the Treatment of Bone Metastases in Patients With Advanced Breast Cancer: A Randomized, Double-Blind Study

(2010) Alison T. Stopeck et al.   JOURNAL OF CLINICAL ONCOLOGY

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

(2009) Masaru Ishii et al.   NATURE

Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis

(2009) Steven R. Cummings et al.   NEW ENGLAND JOURNAL OF MEDICINE

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE