Sensitive quantitative detection of SARS-CoV-2 in clinical samples using digital warm-start CRISPR assay

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

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A Novel Coronavirus from Patients with Pneumonia in China, 2019

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U1 snRNP regulates cancer cell migration and invasion in vitro

(2020) Jung-Min Oh et al.   Nature Communications

“Sample-to-Answer” Detection of Rare ctDNA Mutation from 2 mL Plasma with a Fully Integrated DNA Extraction and Digital Droplet PCR Microdevice for Liquid Biopsy

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A Reverse-Transcription Recombinase-Aided Amplification Assay for Rapid Detection of the 2019 Novel Coronavirus (SARS-CoV-2)

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Rapid detection of SARS-CoV-2 by low volume real-time single tube reverse transcription recombinase polymerase amplification using an exo probe with an internally linked quencher (exo-IQ)

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Rapid Detection of COVID-19 Coronavirus Using a Reverse Transcriptional Loop-Mediated Isothermal Amplification (RT-LAMP) Diagnostic Platform

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A multiple center clinical evaluation of an ultra-fast single-tube assay for SARS-CoV-2 RNA

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CRISPR–Cas12-based detection of SARS-CoV-2

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Single-copy sensitive, field-deployable, and simultaneous dual-gene detection of SARS-CoV-2 RNA via modified RT–RPA

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Molecular Diagnosis of COVID-19: Challenges and Research Needs

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Rapid and visual detection of 2019 novel coronavirus (SARS-CoV-2) by a reverse transcription loop-mediated isothermal amplification assay

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A Self-Priming Digital Polymerase Chain Reaction Chip for Multiplex Genetic Analysis

(2020) Juxin Yin et al.   ACS Nano

Diagnostics for SARS-CoV-2 detection: A comprehensive review of the FDA-EUA COVID-19 testing landscape

(2020) Neeraja Ravi et al.   BIOSENSORS & BIOELECTRONICS

Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2

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Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing

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SARS-CoV-2 detection using isothermal amplification and a rapid, inexpensive protocol for sample inactivation and purification

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Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection

(2020) Long T. Nguyen et al.   Nature Communications

Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA

(2020) Maturada Patchsung et al.   Nature Biomedical Engineering

An Ultralocalized Cas13a Assay Enables Universal and Nucleic Acid Amplification-Free Single-Molecule RNA Diagnostics

(2020) Tian Tian et al.   ACS Nano

Isothermal Amplification and Ambient Visualization in a Single Tube for the Detection of SARS-CoV-2 Using Loop-Mediated Amplification and CRISPR Technology

(2020) Bo Pang et al.   ANALYTICAL CHEMISTRY

opvCRISPR: One-pot visual RT-LAMP-CRISPR platform for SARS-cov-2 detection

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Digital CRISPR/Cas‐Assisted Assay for Rapid and Sensitive Detection of SARS‐CoV‐2

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Dual-Priming Isothermal Amplification (DAMP) for Highly Sensitive and Specific Molecular Detection with Ultralow Nonspecific Signals

(2019) Xiong Ding et al.   ANALYTICAL CHEMISTRY

Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single cell resolution

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Quantification of HIV-DNA and residual viremia in patients starting ART by droplet digital PCR: Their dynamic decay and correlations with immunological parameters and virological success

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Digital PCR—An Emerging Technology with Broad Applications in Microbiology

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Phosphorothioated Primers Lead to Loop-Mediated Isothermal Amplification at Low Temperatures

(2018) Sheng Cai et al.   ANALYTICAL CHEMISTRY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

Digital PCR as a tool to measure HIV persistence

(2018) Sofie Rutsaert et al.   Retrovirology

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

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Next-generation diagnostics with CRISPR

(2018) Daniel S. Chertow   SCIENCE

Smartphone-based mobile digital PCR device for DNA quantitative analysis with high accuracy

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Self-powered integrated microfluidic point-of-care low-cost enabling (SIMPLE) chip

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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

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Detection and Spatial Mapping of Mercury Contamination in Water Samples Using a Smart-Phone

(2014) Qingshan Wei et al.   ACS Nano

Fluorescent Imaging of Single Nanoparticles and Viruses on a Smart Phone

(2013) Qingshan Wei et al.   ACS Nano

Digital LAMP in a sample self-digitization (SD) chip

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Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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