Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity

Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

(2020) Mohammed T.-E. Maghraby et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Recent advancements in the development of heterocyclic anti-inflammatory agents

(2020) Sahil Sharma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors

(2020) Heba E. Hashem et al.   MOLECULES

Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential

(2019) Ola S. Afifi et al.   BIOORGANIC CHEMISTRY

Design, synthesis, modeling studies and biological screening of novel pyrazole derivatives as potential analgesic and anti-inflammatory agents

(2019) Azza T. Taher et al.   BIOORGANIC CHEMISTRY

Anti-Inflammatory and Anti-Hyperuricemic Functions of Two Synthetic Hybrid Drugs with Dual Biological Active Sites

(2019) Rafa S. Almeer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX

(2018) Yasser M. Omar et al.   BIOORGANIC CHEMISTRY

Synthesis, Spectral Characterization, Cytotoxic, and Antimicrobial Activities of Some Novel Heterocycles Utilizing 1,3-Diphenylpyrazole-4-carboxaldehyde Thiosemicarbazone

(2018) Sayed K. Ramadan et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Thiazoles and Thiazolidinones as COX/LOX Inhibitors

(2018) et al.   MOLECULES

Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents

(2017) Eman Nossier et al.   MOLECULES

Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR

(2016) Eman K.A. Abdelall et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

NSAID-induced Gastrointestinal Injury

(2016) James M. Scheiman   JOURNAL OF CLINICAL GASTROENTEROLOGY

Multimodal analgesia: A systematic review of local NSAIDs for non-ophthalmologic postoperative pain management

(2016) Lisa Brubaker et al.   International Journal of Surgery

Synthesis of novel pyrazole–thiadiazole hybrid as potential potent and selective cyclooxygenase-2 (COX-2) inhibitors

(2014) S.G. Alegaon et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents

(2014) S.G. Alegaon et al.   BIOORGANIC CHEMISTRY

Benzimidazole: An emerging scaffold for analgesic and anti-inflammatory agents

(2014) Monika Gaba et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The therapeutic journey of benzimidazoles: A review

(2012) Yogita Bansal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Analogue-based design, synthesis and molecular docking analysis of 2,3-diaryl quinazolinones as non-ulcerogenic anti-inflammatory agents

(2011) E. Manivannan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: An analogue-based drug design approach

(2009) Ritesh N. Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety

(2008) Mohamed R. Shaaban et al.   BIOORGANIC & MEDICINAL CHEMISTRY

TNF-mediated inflammatory disease

(2007) JR Bradley   JOURNAL OF PATHOLOGY