4.5 Article

Synthesis and anti-tumor activity of marine alkaloids

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 41, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2021.128009

Keywords

Marine alkaloid; Synthesis; Anti-tumor activity

Funding

  1. key project of science and technology research program of Chongqing Education Commission of China [KJZD-K202000503]
  2. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry [20151098]
  3. Chongqing Key Research Project of Basic Science & Frontier Technology [cstc2017jcyjBX0012]

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Marine alkaloids were categorized into five groups based on their anti-tumor activity. The optimization process, chemical synthesis, anti-tumor activity evaluation and structure-activity relationship of various compounds were discussed.
Marine alkaloids were divided into five categories from the perspective of anti-tumor activity. The optimization process, chemical synthesis, anti-tumor activity evaluation and structure?activity relationship of various com-pounds were discussed.

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