Promising anti-SARS-CoV-2 drugs by effective dual targeting against the viral and host proteases

Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations

(2021) Chun-Hui Zhang et al.   ACS Central Science

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

(2020) Guangdi Li et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics

(2020) Jinnong Zhang et al.   Lancet Respiratory Medicine

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

Drug Development and Medicinal Chemistry Efforts toward SARS‐Coronavirus and Covid‐19 Therapeutics

(2020) Arun K. Ghosh et al.   ChemMedChem

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

(2020) Linlin Zhang et al.   SCIENCE

Drug treatment options for the 2019-new coronavirus (2019-nCoV)

(2020) Hongzhou Lu   BioScience Trends

Homology modeling and in silico design of novel and potential dual-acting inhibitors of human histone deacetylases HDAC5 and HDAC9 isozymes

(2020) Ammar D. Elmezayen et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

The SARS-CoV-2 main protease as drug target

(2020) Sven Ullrich et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2

(2020) Ahmed Mostafa et al.   Pharmaceuticals

Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation

(2019) Jessica C. de Greef et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetically Engineered Cell-Derived Nanoparticles for Targeted Breast Cancer Immunotherapy

(2019) Xiaojing Shi et al.   MOLECULAR THERAPY

Development and Testing of Druglike Screening Libraries

(2018) Junmei Wang et al.   Journal of Chemical Information and Modeling

Proteases and protease inhibitors in infectious diseases

(2017) Ayodeji A. Agbowuro et al.   MEDICINAL RESEARCH REVIEWS