Tumor hypoxia-activated combinatorial nanomedicine triggers systemic antitumor immunity to effectively eradicate advanced breast cancer

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

(2020) John D. Martin et al.   Nature Reviews Clinical Oncology

Translational Nanomedicine Boosts Anti-PD1 Therapy to Eradicate Orthotopic PTEN-Negative Glioblastoma

(2020) Hiroaki Kinoh et al.   ACS Nano

Clinical development and potential of photothermal and photodynamic therapies for cancer

(2020) Xingshu Li et al.   Nature Reviews Clinical Oncology

Cancer immunotherapy comes of age and looks for maturity

(2020) Amanda Finck et al.   Nature Communications

A Semiconducting Polymer Nano-prodrug for Hypoxia-Activated Photodynamic Cancer Therapy

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Combining Nanomedicine and Immunotherapy

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Engineering Magnetosomes for Ferroptosis/Immunomodulation Synergism in Cancer

(2019) Fan Zhang et al.   ACS Nano

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Self‐Amplified Drug Delivery with Light‐Inducible Nanocargoes to Enhance Cancer Immunotherapy

(2019) Bing Feng et al.   ADVANCED MATERIALS

Redox-Activated Porphyrin-Based Liposome Remote-Loaded with Indoleamine 2,3-Dioxygenase (IDO) Inhibitor for Synergistic Photoimmunotherapy through Induction of Immunogenic Cell Death and Blockage of IDO Pathway

(2019) Dechun Liu et al.   NANO LETTERS

Co-localized delivery of nanomedicine and nanovaccine augments the postoperative cancer immunotherapy by amplifying T-cell responses

(2019) Xiang Liu et al.   BIOMATERIALS

Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect

(2018) Zhikuan Chen et al.   ACS Nano

Hypoxia and acidosis: immune suppressors and therapeutic targets

(2018) Sultan Damgaci et al.   IMMUNOLOGY

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

(2018) Jutaek Nam et al.   Nature Communications

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

Interferon gamma in cancer immunotherapy

(2018) Ling Ni et al.   Cancer Medicine

Acidity/Reducibility Dual-Responsive Hollow Mesoporous Organosilica Nanoplatforms for Tumor-Specific Self-Assembly and Synergistic Therapy

(2018) Wei Tang et al.   ACS Nano

Cancer immunotherapy: the beginning of the end of cancer?

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Overcoming the Achilles' heel of photodynamic therapy

(2016) Wenpei Fan et al.   CHEMICAL SOCIETY REVIEWS

A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy

(2016) Peng Mi et al.   Nature Nanotechnology

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Hybrid Calcium Phosphate-Polymeric Micelles Incorporating Gadolinium Chelates for Imaging-Guided Gadolinium Neutron Capture Tumor Therapy

(2015) Peng Mi et al.   ACS Nano

Dually pH/Reduction-Responsive Vesicles for Ultrahigh-Contrast Fluorescence Imaging and Thermo-Chemotherapy-Synergized Tumor Ablation

(2015) Aijun Zhu et al.   ACS Nano

Development of individualized anti-metastasis strategies by engineering nanomedicines

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Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery

(2015) Jicheng Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer

(2014) Takahiro Nomoto et al.   Nature Communications

IL-12p70–producing patient DC vaccine elicits Tc1-polarized immunity

(2013) Beatriz M. Carreno et al.   JOURNAL OF CLINICAL INVESTIGATION

Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer

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Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer

(2013) Charles G. Drake et al.   Nature Reviews Clinical Oncology

Tumour Hypoxia Affects the Responsiveness of Cancer Cells to Chemotherapy and Promotes Cancer Progression

(2012) Jean-Philippe Cosse et al.   Anti-Cancer Agents in Medicinal Chemistry

Multifunctional Core-Shell Upconverting Nanoparticles for Imaging and Photodynamic Therapy of Liver Cancer Cells

(2012) Zengxia Zhao et al.   Chemistry-An Asian Journal

CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients

(2012) A. J. Rech et al.   Science Translational Medicine

Effect of mesenchymal stem cells on hypoxia-induced desensitization of β2-adrenergic receptors in rat osteosarcoma cells

(2012) AKIRA KIDO et al.   Oncology Letters

Tumor Metastasis: Molecular Insights and Evolving Paradigms

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Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Enhanced Tumor Eradication by Combining CTLA-4 or PD-1 Blockade With CpG Therapy

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Hypoxia and Radiation Therapy: Past History, Ongoing Research, and Future Promise

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Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α

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Generation of Oxygen Deficiency in Cell Culture Using a Two-Enzyme System to Evaluate Agents Targeting Hypoxic Tumor Cells

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