Article
Biotechnology & Applied Microbiology
Eric Caroca, Mariela Elorrieta, Carolyn Palma, Daniel Navia, Raquel Lebrero, Andrea Carvajal
Summary: This study successfully valorized common bean pods through a sequential process of SSF with the WRF T. versicolor and SSAD, producing stable and effective enzymes as well as biogas from the remaining solids.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Physical
S. S. Timofeeva, J. V. Karaeva, A. A. Kovalev, D. A. Kovalev, Yu. V. Litti
Summary: This study investigates the possibility of using steam gasification of digestates after anaerobic digestion and dark fermentation to obtain syngas with high hydrogen content. The syngas from digestates after dark fermentation has a high H2/CO ratio, making it promising for conversion to liquid fuel through Fischer-Tropsch synthesis. This research is significant for the processing of agricultural industrial waste and the production of high value-added products.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Review
Agricultural Engineering
Dibyajyoti Haldar, Asma Musfira Shabbirahmed, Reeta Rani Singhania, Chiu-Wen Chen, Cheng-Di Dong, Vinoth Kumar Ponnusamy, Anil Kumar Patel
Summary: Increased urbanization and industrialization have led to higher energy demand, increased waste output, and negative environmental impacts. This highlights the need for effective solid-waste-management policies, particularly for food waste. The global generation of food waste is estimated at 1.6 gigatons per year, with an economic value of 750 billion USD. However, the diverse composition and varying moisture content of food waste pose challenges in transforming it into value-added products. This review comprehensively discusses the socio-economic challenges and environmental concerns associated with solid waste management, and critically reviews engineering aspects for efficient food waste management.
BIORESOURCE TECHNOLOGY
(2022)
Article
Agricultural Engineering
Michal Piatek, Aleksander Lisowski, Magdalena Dabrowska
Summary: Lignocellulose is a major substrate for biogas production, requiring proper pretreatment for increased yield; solid lignin can have long-term inhibitory effects on hydrolysis and methanogenesis; a new method was developed to model these effects, showing the potential impact on biomethane production.
BIORESOURCE TECHNOLOGY
(2021)
Review
Engineering, Environmental
Sonil Nanda, Franco Berruti
Summary: This paper reviews various waste-to-energy technologies, including traditional thermal incineration and modern hydrothermal incineration, as well as thermochemical and biological conversion technologies for the transformation of solid waste into biofuel products. Furthermore, it comprehensively discusses the current status, opportunities, and challenges of municipal solid waste management.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Najmul Haque Barbhuiya, Ashish Kumar, Ayush Singh, Munish K. Chandel, Christopher J. Arnusch, James M. Tour, Swatantra P. Singh
Summary: The method of flash graphene (FG) production converts bulk quantities of carbonaceous materials into graphene, providing a way to convert various solid wastes containing carbon into valuable products, thus reducing waste volume and enabling resource valorization.
Article
Green & Sustainable Science & Technology
Ahmad Reza Salehiyoun, Hamid Zilouei, Mohammad Safari, Francesco Di Maria, Seyed Hashem Samadi, Omid Norouzi
Summary: This study investigates the effect of biochar addition on the dry anaerobic digestion of organic solid waste. The results show that adding biochar can enhance methane production and yield, control acidification, and shorten the lag phase. However, the synergistic effects at higher biochar doses are limited, and organic waste with a higher C/N ratio obtains less benefits.
Article
Biotechnology & Applied Microbiology
G. Dimitriv Jojoa-Unigarro, Simon Gonzalez-Martinez
Summary: Thermodynamically, lactic acid and ethanol offer the highest energy recovery for methane production compared to other common metabolites. Fermentation of previously processed organic fraction of municipal solid waste (OFMSW) is essential for rapid methane production. This study investigates the fermentation of OFMSW in batch reactors at pH values of 4, 5, and 6, at 35 degrees C. The results demonstrate that lower pH and shorter fermentation times result in higher production of ethanol and lactic acid, and the liquid fractions of fermented OFMSW produce more methane than the solid fractions.
BIOCHEMICAL ENGINEERING JOURNAL
(2023)
Article
Green & Sustainable Science & Technology
Siswo Sumardiono, Gebyar Adisukmo, Muthia Hanif, Budiyono Budiyono, Heri Cahyono
Summary: The study indicates that controlling the particle size of solid sago waste, biological pretreatment, NaOH pretreatment, and the ratio between solid sago waste and cow rumen can improve biogas production rate, with the 1:1 ratio showing the best results.
Review
Environmental Sciences
Himanshu K. Khuntia, Aastha Paliwal, D. Ravi Kumar, H. N. Chanakya
Summary: The sustainable management of organic solid wastes, particularly municipal solid waste (MSW), is crucial for achieving various sustainable development goals (SDGs). Solid-state anaerobic digestion (SSAD) is a biomethanation process that offers advantages over conventional anaerobic slurry digesters, such as smaller footprint, lower freshwater consumption, and simpler upstream and downstream processes. This review critically assesses different aspects of SSAD, including bioreactor design, operational strategy, process performance, microbial ecology, applications, and mathematical models. The evaluation revealed various challenges and factors influencing the success of SSAD, such as process failures and the role of microbial acclimatization in enhancing performance.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2022)
Article
Engineering, Environmental
Mario F. Castellon-Zelaya, Simon Gonzalez-Martinez
Summary: The study shows that the production of metabolites during silage increases with decreasing solids concentration regardless of the temperature, and methane production from ensiled OFMSW at 10% solids concentration is better than from fresh OFMSW under all tested conditions. Ensiled OFMSW produces more methane than fresh OFMSW, and methane production is highest at 35 degrees C.
WATER SCIENCE AND TECHNOLOGY
(2021)
Article
Agricultural Engineering
Shuohui Shi, Meng Cao, Ying Zhang, Xing Fan, Shihu Liu, Jiahao Chen, Jian Zhou
Summary: A thermal-alkali-biofilm pretreatment (TAB) was established to improve the anaerobic digestion of high-solid and low-organic-content sludge. TAB significantly enhanced WAS reduction, hydrolysis/acidogenesis efficiency, and biochemical methane potential by stimulating proteolysis and solubilizing WAS. In addition, biofilm assistance accelerated the elimination of autochthonous bacteria and promoted the enrichment of specialized fermentative microorganisms and relevant functional genes, contributing to enhanced hydrolysis/acidogenesis in TAB.
BIORESOURCE TECHNOLOGY
(2023)
Review
Agricultural Engineering
Ruolin Guan, Hairong Yuan, Shuai Yuan, Beibei Yan, Xiaoyu Zuo, Xiteng Chen, Xiujin Li
Summary: This paper reviewed recent research on anaerobic bioconversion of crop stalks, focusing on the effects of pretreatment methods, AD operation parameters, and technology development on AD performance, and proposed recommendations for future development.
BIORESOURCE TECHNOLOGY
(2022)
Review
Green & Sustainable Science & Technology
T. Angelin Swetha, K. Mohanrasu, Muniyasamy Sudhakar, Rathinam Raja, Kumar Ponnuchamy, Govarthanan Muthusamy, A. Arun
Summary: The bioeconomy is a bio-based economy that utilizes renewable biological resources to develop materials, chemicals, and energy, and it offers a solution to the major challenges faced by humanity in the modern world. By converting waste into bioeconomic products using microbes, the bioeconomy has the potential to make a significant impact with minimal environmental harm.
SUSTAINABLE ENERGY TECHNOLOGIES AND ASSESSMENTS
(2022)
Article
Chemistry, Physical
Marina Tomasini, Mariana De Oliveira Faber, Viridiana Santana Ferreira-Leitao
Summary: Sugarcane straw is not effectively utilized in the industry currently, but sugarcane straw hemicellulose hydrolyzate (HH) shows promise as a raw material for H2 and CH4 production.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Ecology
Trish. O. Nyarumbu, Tinotenda Kaseke, Vimbai Gobvu, Chrispen Murungweni, Arnold. B. Mashingaidze, Zedias Chikwambi
Article
Biotechnology & Applied Microbiology
Reckson Kamusoko, Raphael M. Jingura, Wilson Parawira, Zedias Chikwambi
Summary: This short communication characterizes the proximate composition of locally available lignocellulosic crop residues as potential feedstocks for biogas production. The results show that buffering is needed in anaerobic digestion and wheat straw is considered to be the most competitive feedstock for AD.
BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR
(2022)
Article
Pharmacology & Pharmacy
Vincent Aketch Nyangwara, Tinashe Mazhindu, Zedias Chikwambi, Collen Masimirembwa, Thomas B. Campbell, Margaret Borok, Ntokozo Ndlovu
Summary: This study aims to establish the frequency of doxorubicin-induced cardiotoxicity (DIC) in Zimbabwean breast cancer patients and test the predictive power of genetic biomarkers. A cohort of 50 patients were followed up for 12 months and genotyped for UGTA1A6*4, SLC28A3 and RARG. DIC occurred in 11% of the patients. No association between DIC and the three genetic variants was observed. Larger sample size and longer follow-up time are needed for future studies.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Bianza Tinotenda Mbavha, Roslyn Stella Thelingwani, Zedias Chikwambi, Anna Mary Nyakabau, Collen Masimirembwa
Summary: This study aimed to determine the association between CYP2D6 polymorphisms and endoxifen plasma concentrations in a cohort of Zimbabwean breast cancer patients (n = 40). The results showed that CYP2D6 phenotypes and activity scores were significantly associated with endoxifen plasma concentrations and endoxifen to N-desmethyl-tamoxifen ratios.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Nyasha Lorraine Mapira, Roslyn Stella Thelingwani, Zedias Chikwambi, Patience Kuona, Collen Masimirembwa
Summary: This cross-sectional study in 106 Zimbabwean sickle cell disease (SCD) patients demonstrated the significant correlation between UGT2B7 polymorphism and pain management in SCD patients.
Article
Pharmacology & Pharmacy
Pageneck Chikondowa, Derick Munkombwe, Zedias Chikwambi, Patience Kuona, Collen Masimirembwa
Summary: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy in Zimbabwe. This study aimed to determine the frequency of specific gene polymorphisms and their association with drug intolerance in ALL patients. Genotyping for TPMT and NUDT15 alleles was performed on 41 patients, and the results showed a high frequency (9.8%) of the defective TPMT*3C variant. Although not statistically significant, TPMT*1/*3C patients had a considerably lower median dose intensity compared to TPMT*1/*1 patients. This study highlights the importance of pharmacogenetics testing for safe usage of 6-mercaptopurine in the Zimbabwean population.
Article
Health Care Sciences & Services
Boluwatife Lawrence Afolabi, Tinashe Mazhindu, Chikwambi Zedias, Margaret Borok, Ntokozo Ndlovu, Collen Masimirembwa
Summary: Fluoropyrimidines are commonly used in colorectal cancer treatment, but they come with adverse events, such as gastrointestinal reactions, myelosuppression, and palmar-plantar erythrodysesthesia. Clinical guidelines for fluoropyrimidine dosing based on DPYD genetic polymorphism have been effective in reducing these adverse events in European patients. However, this study found that the known DPYD variants were absent in a Zimbabwean cancer patient cohort, suggesting the need for modification of the guidelines to include minority populations.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Agriculture, Dairy & Animal Science
Ngavaite Chigede, Zedias Chikwambi, Irvin D. T. Mpofu, James Madzimure
Summary: Improper use of antibiotics in livestock products has led to an increasing threat of antimicrobial drug resistance (AMR) worldwide. Microorganisms can produce bioactive compounds that can combat AMR. This study isolated, identified, and characterized microbes from broiler birds' gastrointestinal tracts that can produce biosurfactants. The biosurfactants were found to have antibacterial properties, suggesting their potential use as feed additives for broilers.
ANIMAL BIOTECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Marie Madeleine M. Hidjo, Zedias Chikwambi, Gift Ngwende, Jonathan A. Matenga, Collen Masimirembwa
Summary: A prospective observational study was conducted to evaluate the feasibility of implementing clinical guidelines for warfarin dosing in black Zimbabwean patients. Variations in CYP2C9*5, CYP2C9*6, CYP2C9*8, CYP2C9*11, and VKORC1 c. 1639 G>A were observed in 62 study patients. The results showed that the Clinical Pharmacogenetics Implementation Consortium guidelines are suitable for implementation in Zimbabwean patients and could help optimize warfarin dosing.
Article
Biotechnology & Applied Microbiology
Kumbirai Beaton, Allen Mazadza, Zedias Chikwambi
Summary: The study successfully identified the locally grown bananas through genetic and morphological evaluation, marking an important step towards breeding pure line cultivars.
JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY
(2023)