Combining a chimeric antigen receptor and a conventional T-cell receptor to generate T cells expressing two additional receptors (TETARs) for a multi-hit immunotherapy of melanoma

Generation of CD8+T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy

(2015) Sandra Höfflin et al.   CANCER BIOLOGY & THERAPY

Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone

(2015) Christian Krug et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Chimeric Antigen Receptor– and TCR-Modified T Cells Enter Main Street and Wall Street

(2015) David M. Barrett et al.   JOURNAL OF IMMUNOLOGY

Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma

(2015) Laura A. Johnson et al.   Science Translational Medicine

Antibody-modified T cells: CARs take the front seat for hematologic malignancies

(2014) M. V. Maus et al.   BLOOD

Engineered T cells for cancer therapy

(2014) Carl H. June et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Emergence of T-Bodies/CAR T Cells

(2014) Zelig Eshhar et al.   CANCER JOURNAL

Mechanisms of tumor escape from immune system: Role of mesenchymal stromal cells

(2014) Alessandro Poggi et al.   IMMUNOLOGY LETTERS

Molecular architecture of the αβ T cell receptor–CD3 complex

(2014) Michael E. Birnbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

(2013) G. P. Linette et al.   BLOOD

Engineered T cells for cancer treatment

(2013) Usanarat Anurathapan et al.   CYTOTHERAPY

Chimeric antigen receptors for the adoptive T cell therapy of hematologic malignancies

(2013) Marco L. Davila et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity

(2013) Cor HJ Lamers et al.   MOLECULAR THERAPY

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

(2013) Stephan A. Grupp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetically Modified T Cells for the Treatment of Malignant Disease

(2013) Agnieszka Wieczorek et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies

(2013) G. L. Beatty et al.   Cancer Immunology Research

T cell-based gene therapy of cancer

(2012) Saar Gill et al.   Translational Research

Human T cells expressing two additional receptors (TETARs) specific for HIV-1 recognize both epitopes

(2011) C. Hofmann et al.   BLOOD

Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells

(2011) David M. Barrett et al.   HUMAN GENE THERAPY

Treating cancer with genetically engineered T cells

(2011) Tristen S. Park et al.   TRENDS IN BIOTECHNOLOGY

Genetic Modification of T Cells

(2010) Chiara Bonini et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

A High Molecular Weight Melanoma-Associated Antigen-Specific Chimeric Antigen Receptor Redirects Lymphocytes to Target Human Melanomas

(2010) W. R. Burns et al.   CANCER RESEARCH

Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor

(2010) Y. Zhao et al.   CANCER RESEARCH

Selected Murine Residues Endow Human TCR with Enhanced Tumor Recognition

(2010) G. Bialer et al.   JOURNAL OF IMMUNOLOGY

A fast and robust method to clone and functionally validate T-cell receptors

(2009) Katrin Birkholz et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Analysis of HLA class I expression in progressing and regressing metastatic melanoma lesions after immunotherapy

(2008) Rafael Carretero et al.   IMMUNOGENETICS