Manipulating macrophage polarization in cancer patients: From nanoparticles to human chimeric antigen receptor macrophages

LncRNA ANCR Promotes Invasion and Migration of Gastric Cancer by Regulating FoxO1 Expression to Inhibit Macrophage M1 Polarization

(2020) Chunying Xie et al.   DIGESTIVE DISEASES AND SCIENCES

CXCR2‐modified CAR‐T cells have enhanced trafficking ability that improves treatment of hepatocellular carcinoma

(2020) Guangna Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

(2020) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage Migration and Phagocytosis Are Controlled by Kindlin-3's Link to the Cytoskeleton

(2020) Huan Liu et al.   JOURNAL OF IMMUNOLOGY

Immune checkpoint signaling and cancer immunotherapy

(2020) Xing He et al.   CELL RESEARCH

Human chimeric antigen receptor macrophages for cancer immunotherapy

(2020) Michael Klichinsky et al.   NATURE BIOTECHNOLOGY

Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C

(2020) Anna Mary Steitz et al.   Cell Death & Disease

Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization

(2020) Alexandra Pritchard et al.   Cells

Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles

(2020) Tom Haber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway

(2020) Yihan Bai et al.   OncoTargets and Therapy

Lipid accumulation in macrophages confers protumorigenic polarization and immunity in gastric cancer

(2020) Qin Luo et al.   CANCER SCIENCE

Role of M2-like macrophages in the progression of ovarian cancer

(2020) Se Hwan Baek et al.   EXPERIMENTAL CELL RESEARCH

Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1

(2020) Venkatesh Krishnan et al.   Communications Biology

Intravesical In Situ Immunostimulatory Gel for Triple Therapy of Bladder Cancer

(2020) Pengyu Guo et al.   ACS Applied Materials & Interfaces

Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

(2020) Linnéa La Fleur et al.   CANCER RESEARCH

STING agonist promotes CAR T cell trafficking and persistence in breast cancer

(2020) Nuo Xu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Astragaloside IV antagonizes M2 phenotype macrophage polarization-evoked ovarian cancer cell malignant progression by suppressing the HMGB1–TLR4 axis

(2020) Xue Wang et al.   MOLECULAR IMMUNOLOGY

Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRPɑ axis

(2019) Hongcheng Yang et al.   Cancer Medicine

Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene

(2019) Mark A. Sellmyer et al.   MOLECULAR THERAPY

Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer

(2019) Wei Li et al.   Cell Death & Disease

Distinct Migratory Properties of M1, M2, and Resident Macrophages Are Regulated by αDβ2 and αMβ2 Integrin-Mediated Adhesion

(2018) Kui Cui et al.   Frontiers in Immunology

CAR T cells ready to go mainstream

(2016) Diana Romero   Nature Reviews Clinical Oncology

Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization

(2016) K. Newick et al.   Cancer Immunology Research

Activated Macrophage Survival Is Coordinated by TAK1 Binding Proteins

(2014) September R. Mihaly et al.   PLoS One

Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma

(2013) Matteo Santoni et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid cells as effector cells for monoclonal antibody therapy of cancer

(2013) Rens Braster et al.   METHODS

Macrophage Migration and Invasion Is Regulated by MMP10 Expression

(2013) Megan Y. Murray et al.   PLoS One

Effective Phagocytosis of Low Her2 Tumor Cell Lines with Engineered, Aglycosylated IgG Displaying High FcγRIIa Affinity and Selectivity

(2012) Sang Taek Jung et al.   ACS Chemical Biology

Critical Role for Antiapoptotic Bcl-xL and Mcl-1 in Human Macrophage Survival and Cellular IAP1/2 (cIAP1/2) in Resistance to HIV-Vpr-induced Apoptosis

(2012) Aurelia Busca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and consequences of macrophage apoptosis in atherosclerosis

(2008) Tracie Seimon et al.   JOURNAL OF LIPID RESEARCH