Soluble Methane Monooxygenase Component Interactions Monitored by 19F NMR

Assignments of 19F NMR resonances and exploration of dynamics in a long-chain flavodoxin

(2021) Taylor A. Varner et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein

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Expression, purification, and functional reconstitution of 19F-labeled cytochrome b5 in peptide nanodiscs for NMR studies

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19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2

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Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A

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Structural Studies of the Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel

(2020) Jason C. Jones et al.   BIOCHEMISTRY

High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States

(2020) Vivek Srinivas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Soluble Methane Monooxygenase

(2019) Rahul Banerjee et al.   Annual Review of Biochemistry

Side-Chain Dynamics of the Trifluoroacetone Cysteine Derivative Characterized by 19F NMR Relaxation and Molecular Dynamics Simulations

(2019) Suad Rashid et al.   JOURNAL OF PHYSICAL CHEMISTRY B

SAR by (Protein-Observed) 19F NMR

(2019) Anand Divakaran et al.   ACCOUNTS OF CHEMICAL RESEARCH

2-Fluorotyrosine is a valuable but understudied amino acid for protein-observed 19F NMR

(2019) Peter D. Ycas et al.   JOURNAL OF BIOMOLECULAR NMR

Dioxygen Activation by Nonheme Diiron Enzymes: Diverse Dioxygen Adducts, High-Valent Intermediates, and Related Model Complexes

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Defining a conformational ensemble that directs activation of PPARγ

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Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells

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High-Resolution Extended X-ray Absorption Fine Structure Analysis Provides Evidence for a Longer Fe···Fe Distance in the Q Intermediate of Methane Monooxygenase

(2018) George E. Cutsail et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In-crystal reaction cycle of a toluene-bound diiron hydroxylase

(2017) Justin F. Acheson et al.   NATURE

A tale of two methane monooxygenases

(2016) Matthew O. Ross et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Protein-observed 19F-NMR for fragment screening, affinity quantification and druggability assessment

(2016) Clifford T Gee et al.   Nature Protocols

Structure of T4moF, the Toluene 4-Monooxygenase Ferredoxin Oxidoreductase

(2015) Justin F. Acheson et al.   BIOCHEMISTRY

Protein-Observed Fluorine NMR: A Bioorthogonal Approach for Small Molecule Discovery

(2015) Keith E. Arntson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Single Turnover Reveals Oxygenated Intermediates in Toluene/o-Xylene Monooxygenase in the Presence of the Native Redox Partners

(2015) Alexandria Deliz Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorinated Aromatic Amino Acids Are Sensitive 19F NMR Probes for Bromodomain-Ligand Interactions

(2014) Neeraj K. Mishra et al.   ACS Chemical Biology

Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy

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Fluorine as a Hydrogen-Bond Acceptor: Experimental Evidence and Computational Calculations

(2014) Claudio Dalvit et al.   CHEMISTRY-A EUROPEAN JOURNAL

Electron Transfer Control in Soluble Methane Monooxygenase

(2014) Weixue Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diiron Oxidation State Control of Substrate Access to the Active Site of Soluble Methane Monooxygenase Mediated by the Regulatory Component

(2014) Weixue Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for biomolecular recognition in overlapping binding sites in a diiron enzyme system

(2014) Justin F. Acheson et al.   Nature Communications

Intermediate P* from Soluble Methane Monooxygenase Contains a Diferrous Cluster

(2013) Rahul Banerjee et al.   BIOCHEMISTRY

Control of substrate access to the active site in methane monooxygenase

(2013) Seung Jae Lee et al.   NATURE

Simple and inexpensive incorporation of 19F-Tryptophan for protein NMR spectroscopy

(2012) Peter B. Crowley et al.   CHEMICAL COMMUNICATIONS

Dioxygen Activation in Soluble Methane Monooxygenase

(2011) Christine E. Tinberg et al.   ACCOUNTS OF CHEMICAL RESEARCH

Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b

(2010) Nates An Elango et al.   PROTEIN SCIENCE

Revisiting the Mechanism of Dioxygen Activation in Soluble Methane Monooxygenase fromM. capsulatus(Bath): Evidence for a Multi-Step, Proton-Dependent Reaction Pathway

(2009) Christine E. Tinberg et al.   BIOCHEMISTRY

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

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CD and MCD Studies of the Effects of Component B Variant Binding on the Biferrous Active Site of Methane Monooxygenase†

(2008) Nataša Mitić et al.   BIOCHEMISTRY

Structural consequences of effector protein complex formation in a diiron hydroxylase

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