MATR3 F115C knock-in mice do not exhibit motor defects or neuropathological features of ALS

Knockdown of genes involved in axonal transport enhances the toxicity of human neuromuscular disease‐linked MATR3 mutations in Drosophila

(2020) Melody Zhao et al.   FEBS LETTERS

Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred

(2020) Sara Saez-Atienzar et al.   NEUROLOGY

Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS

(2020) Ching Serena Kao et al.   Nature Communications

RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

(2020) Nandini Ramesh et al.   Acta Neuropathologica Communications

Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes

(2020) David X. Medina et al.   Stem Cell Research

Mutant TDP-43 Causes Early-Stage Dose-Dependent Motor Neuron Degeneration in a TARDBP Knockin Mouse Model of ALS

(2019) Sarah Y. Ebstein et al.   Cell Reports

Mutant MATR3 mouse model to explain multisystem proteinopathy

(2019) Xiao Zhang et al.   JOURNAL OF PATHOLOGY

Genetics of amyotrophic lateral sclerosis: A review

(2019) Stéphane Mathis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis

(2019) Gina Picchiarelli et al.   NATURE NEUROSCIENCE

Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization

(2018) Ahmed M Malik et al.   eLife

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing

(2018) Jan Attig et al.   CELL

Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

(2018) Christina Moloney et al.   Acta Neuropathologica Communications

Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing

(2017) Ayan Banerjee et al.   NUCLEIC ACIDS RESEARCH

Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications

(2017) Jia Liu et al.   Frontiers in Immunology

ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export

(2017) Ashley Boehringer et al.   Scientific Reports

Gene discovery in amyotrophic lateral sclerosis: implications for clinical management

(2016) Ammar Al-Chalabi et al.   Nature Reviews Neurology

Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS

(2016) Melanie Lalancette-Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB

(2015) M. B. Coelho et al.   EMBO JOURNAL

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

(2014) Janel O Johnson et al.   NATURE NEUROSCIENCE

The involvement of the cerebellum in amyotrophic lateral sclerosis

(2013) Tino Prell et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

The Role of Immune and Inflammatory Mechanisms in ALS

(2011) P. A. McCombe et al.   CURRENT MOLECULAR MEDICINE

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Matrin 3 Binds and Stabilizes mRNA

(2011) Maayan Salton et al.   PLoS One

The “Dying-Back” Phenomenon of Motor Neurons in ALS

(2010) Michal Dadon-Nachum et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Autosomal-Dominant Distal Myopathy Associated with a Recurrent Missense Mutation in the Gene Encoding the Nuclear Matrix Protein, Matrin 3

(2009) Jan Senderek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Gamma and alpha motor neurons distinguished by expression of transcription factor Err3

(2009) A. Friese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA