Genomics advances the study of inbreeding depression in the wild

Evidence of the phenotypic expression of a lethal recessive allele under inbreeding in a wild population of conservation concern

(2016) Amanda E. Trask et al.   JOURNAL OF ANIMAL ECOLOGY

Genomic analysis reveals depression due to both individual and maternal inbreeding in a free-living mammal population

(2016) Camillo Bérénos et al.   MOLECULAR ECOLOGY

Harnessing the power of RADseq for ecological and evolutionary genomics

(2016) Kimberly R. Andrews et al.   NATURE REVIEWS GENETICS

Inbreeding depression across the lifespan in a wild mammal population

(2016) Jisca Huisman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pedigrees or markers: Which are better in estimating relatedness and inbreeding coefficient?

(2016) Jinliang Wang   THEORETICAL POPULATION BIOLOGY

inbreedR: anRpackage for the analysis of inbreeding based on genetic markers

(2016) Martin A. Stoffel et al.   Methods in Ecology and Evolution

Inferring Population Size History from Large Samples of Genome-Wide Molecular Data - An Approximate Bayesian Computation Approach

(2016) Simon Boitard et al.   PLoS Genetics

Accurate Non-parametric Estimation of Recent Effective Population Size from Segments of Identity by Descent

(2015) Sharon R. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Investigation of regions impacting inbreeding depression and their association with the additive genetic effect for United States and Australia Jersey dairy cattle

(2015) Jeremy T. Howard et al.   BMC GENOMICS

The influence of captive breeding management on founder representation and inbreeding in the ‘Alalā, the Hawaiian crow

(2015) Philip W. Hedrick et al.   CONSERVATION GENETICS

Extremely low genetic variation in endangered Tatra chamois and evidence for hybridization with an introduced Alpine population

(2015) Barbora Zemanová et al.   CONSERVATION GENETICS

Valid estimates of individual inbreeding coefficients from marker-based pedigrees are not feasible in wild populations with low allelic diversity

(2015) Helen R. Taylor et al.   CONSERVATION GENETICS

Complete Genomes Reveal Signatures of Demographic and Genetic Declines in the Woolly Mammoth

(2015) Eleftheria Palkopoulou et al.   CURRENT BIOLOGY

Homozygosity mapping and whole-genome sequencing reveals a deep intronic PROM1 mutation causing cone–rod dystrophy by pseudoexon activation

(2015) Anja K Mayer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Quantifying realized inbreeding in wild and captive animal populations

(2015) U Knief et al.   HEREDITY

Measuring individual inbreeding in the age of genomics: marker-based measures are better than pedigrees

(2015) M Kardos et al.   HEREDITY

Demographic inferences using short-read genomic data in an approximate Bayesian computation framework: in silico evaluation of power, biases and proof of concept in Atlantic walrus

(2015) Aaron B. A. Shafer et al.   MOLECULAR ECOLOGY

Whole-genome resequencing of extreme phenotypes in collared flycatchers highlights the difficulty of detecting quantitative trait loci in natural populations

(2015) Marty Kardos et al.   Molecular Ecology Resources

Evolution of Darwin’s finches and their beaks revealed by genome sequencing

(2015) Sangeet Lamichhaney et al.   NATURE

Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon

(2015) Nicola J. Barson et al.   NATURE

Examining the cause of high inbreeding depression: analysis of whole-genome sequence data in 28 selfed progeny of Eucalyptus grandis

(2015) Philip W. Hedrick et al.   NEW PHYTOLOGIST

Mutations in the heat-shock protein A9 (HSPA9) gene cause the EVEN-PLUS syndrome of congenital malformations and skeletal dysplasia

(2015) Beryl Royer-Bertrand et al.   Scientific Reports

The use and abuse of genetic marker-based estimates of relatedness and inbreeding

(2015) Helen R. Taylor   Ecology and Evolution

Habitat fragmentation and its lasting impact on Earth's ecosystems

(2015) N. M. Haddad et al.   Science Advances

FSuite: exploiting inbreeding in dense SNP chip and exome data

(2014) Steven Gazal et al.   BIOINFORMATICS

Population structure, inbreeding and local adaptation within an endangered riverine specialist: the nase (Chondrostoma nasus)

(2014) Alan G. Hudson et al.   CONSERVATION GENETICS

Inbreeding and runs of homozygosity: A possible solution to an old problem

(2014) Ino Curik et al.   Livestock Science

Relatedness in the post-genomic era: is it still useful?

(2014) Doug Speed et al.   NATURE REVIEWS GENETICS

High-throughput sequencing reveals inbreeding depression in a natural population

(2014) J. I. Hoffman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor

(2014) Matthew C. Keller et al.   PLoS Genetics

Detecting Identity by Descent and Estimating Genotype Error Rates in Sequence Data

(2013) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identity by Descent: Variation in Meiosis, Across Genomes, and in Populations

(2013) E. A. Thompson   GENETICS

Estimating genome-wide heterozygosity: effects of demographic history and marker type

(2013) J M Miller et al.   HEREDITY

Life history trade-offs at a single locus maintain sexually selected genetic variation

(2013) Susan E. Johnston et al.   NATURE

Genome sequencing and population genomics in non-model organisms

(2013) Hans Ellegren   TRENDS IN ECOLOGY & EVOLUTION

Length Distributions of Identity by Descent Reveal Fine-Scale Demographic History

(2012) Pier Francesco Palamara et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic Patterns of Homozygosity in Worldwide Human Populations

(2012) Trevor J. Pemberton et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Understanding and Predicting the Fitness Decline of Shrunk Populations: Inbreeding, Purging, Mutation, and Standard Selection

(2012) A. Garcia-Dorado   GENETICS

Heterozygosity-fitness correlations in zebra finches: microsatellite markers can be better than their reputation

(2012) WOLFGANG FORSTMEIER et al.   MOLECULAR ECOLOGY

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Evidence of Inbreeding Depression on Human Height

(2012) Ruth McQuillan et al.   PLoS Genetics

Translating Effects of Inbreeding Depression on Component Vital Rates to Overall Population Growth in Endangered Bighorn Sheep

(2011) HEATHER E. JOHNSON et al.   CONSERVATION BIOLOGY

Widespread inbreeding and unexpected geographic patterns of genetic variation in eastern hemlock (Tsuga canadensis), an imperiled North American conifer

(2011) Kevin M. Potter et al.   CONSERVATION GENETICS

Quantification of Inbreeding Due to Distant Ancestors and Its Detection Using Dense Single Nucleotide Polymorphism Data

(2011) Matthew C. Keller et al.   GENETICS

Variation in actual relationship as a consequence of Mendelian sampling and linkage

(2011) W.G. HILL et al.   Genetics Research

Combining US and Brazilian Microsatellite Data for a Meta-Analysis of Sheep (Ovis aries) Breed Diversity: Facilitating the FAO Global Plan of Action for Conserving Animal Genetic Resources

(2011) Samuel Rezende Paiva et al.   JOURNAL OF HEREDITY

Risk of breast and prostate cancer is not associated with increased homozygosity in outbred populations

(2010) Victor Enciso-Mora et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Regions of homozygosity and their impact on complex diseases and traits

(2010) Chee Seng Ku et al.   HUMAN GENETICS

On the use of large marker panels to estimate inbreeding and relatedness: empirical and simulation studies of a pedigreed zebra finch population typed at 771 SNPs

(2010) ANNA W. SANTURE et al.   MOLECULAR ECOLOGY

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Reconciling the analysis of IBD and IBS in complex trait studies

(2010) Joseph E. Powell et al.   NATURE REVIEWS GENETICS

Genomics and the future of conservation genetics

(2010) Fred W. Allendorf et al.   NATURE REVIEWS GENETICS

Genomic Runs of Homozygosity Record Population History and Consanguinity

(2010) Mirna Kirin et al.   PLoS One

Approximate Bayesian Computation (ABC) in practice

(2010) Katalin Csilléry et al.   TRENDS IN ECOLOGY & EVOLUTION

Combining genetic and ecological data to assess the conservation status of the endangered Ethiopian walia ibex

(2009) B. Gebremedhin et al.   ANIMAL CONSERVATION

Integrating population genetics and conservation biology in the era of genomics

(2009) N. J. Ouborg   Biology Letters

A quantitative review of heterozygosity-fitness correlations in animal populations

(2009) J. R. CHAPMAN et al.   MOLECULAR ECOLOGY

The genetics of inbreeding depression

(2009) Deborah Charlesworth et al.   NATURE REVIEWS GENETICS

No evidence for excess runs of homozygosity in bipolar disorder

(2009) Anna E. Vine et al.   PSYCHIATRIC GENETICS

Inferring the Joint Demographic History of Multiple Populations from Multidimensional SNP Frequency Data

(2009) Ryan N. Gutenkunst et al.   PLoS Genetics

Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

(2009) Chris C. A. Spencer et al.   PLoS Genetics

Runs of Homozygosity in European Populations

(2008) Ruth McQuillan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide autozygosity mapping in human populations

(2008) Shuang Wang et al.   GENETIC EPIDEMIOLOGY

Analysis of founder-specific inbreeding depression on birth weight in Ripollesa lambs1

(2008) J. Casellas et al.   JOURNAL OF ANIMAL SCIENCE

Highly effective SNP-based association mapping and management of recessive defects in livestock

(2008) Carole Charlier et al.   NATURE GENETICS

Wild pedigrees: the way forward

(2008) J.M Pemberton   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The genealogy and genetic viability of reintroduced Yellowstone grey wolves

(2007) BRIDGETT M. VONHOLDT et al.   MOLECULAR ECOLOGY