Article
Oncology
S. -A. Im, A. Gennari, Y. H. Park, J. H. Kim, Z. -F. Jiang, S. Gupta, T. H. Fadjari, K. Tamura, M. Y. Mastura, M. L. T. Abesamis-Tiambeng, E. H. Lim, C. -H. Lin, A. Sookprasert, N. Parinyanitikul, L. -M. Tseng, S. -C. Lee, P. Caguioa, M. Singh, Y. Naito, R. A. Hukom, B. K. Smruti, S. -S. Wang, S. B. Kim, K. -H. Lee, H. K. Ahn, S. Peters, T. W. Kim, T. Yoshino, G. Pentheroudakis, G. Curigliano, N. Harbeck
Summary: The most recent version of the ESMO Clinical Practice Guidelines for metastatic breast cancer was published in 2021. In 2022, a special hybrid guidelines meeting was held to adapt these guidelines to the Asian context, with input from Asian oncology societies. The aim is to provide harmonized management of MBC patients across Asia.
Article
Medicine, General & Internal
Armaan Singh, Max J. Hyman, Parth K. Modi
Summary: In this cross-sectional study, it was found that advanced practice clinicians (APCs) in the US receive lower financial benefits from pharmaceutical and medical device companies compared to physicians. The study also reveals that the average value of industry interactions with APCs is lower than that with physicians.
Editorial Material
Oncology
Manish A. Shah, Wayne L. Hofstetter, Erin B. Kennedy
Summary: The ASCO Rapid Recommendations Updates aim to disseminate updated recommendations in a timely manner to provide better information on cancer care.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Review
Medicine, General & Internal
Dimitrios Nasioudis, Erin M. George, Janos L. Tanyi
Summary: Approximately 10-25% of patients with locally advanced cervical cancer have metastases to the para-aortic lymph nodes. PET-CT and surgical staging are important for accurate treatment planning, as imaging techniques can have high false negative rates. However, the impact of para-aortic lymphadenectomy on patient outcomes is still controversial.
Review
Oncology
He Zhang, Weimin Kong, Shuning Chen, Xiaoling Zhao, Dan Luo, Yunkai Xie
Summary: Locally advanced cervical cancer has high recurrence and metastasis rate, and low survival rate under standard treatment. Recent studies have shown that surgical staging is more accurate in determining lymph node metastasis and brings survival benefits to some patients. However, the indications for surgical staging and whether it can improve prognosis are still controversial.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
R. Kanesvaran, E. Castro, A. Wong, K. Fizazi, M. L. K. Chua, Y. Zhu, H. Malhotra, Y. Miura, J. L. Lee, F. L. T. Chong, Y-S Pu, C-C Yen, M. Saad, H. J. Lee, H. Kitamura, K. Prabhash, Q. Zou, G. Curigliano, E. Poon, S. P. Choo, S. Peters, E. Lim, T. Yoshino, G. Pentheroudakis
Summary: To accommodate the specific requirements of prostate cancer treatment in Asia, a special meeting was convened by ESMO and SSO to revise the guidelines published in 2020. These guidelines represent the consensus opinions of prostate cancer treatment experts from Asian countries and aim to provide optimization and harmonization recommendations for the management of prostate cancer patients across different regions in Asia.
Article
Multidisciplinary Sciences
Seung Ho Song, Jun Seok Park, Gyu-Seog Choi, An Na Seo, Soo Yeun Park, Hye Jin Kim, Sung-Min Lee, Ghilsuk Yoon
Summary: The study found a significant association between a short distal resection margin (< 1 cm) and local recurrence in patients with rectal cancer, especially in those with tumor stages ypT2-4.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
T. Yoshino, G. Argiles, E. Oki, E. Martinelli, H. Taniguchi, D. Arnold, Mishima, Y. Li, B. K. Smruti, J. B. Ahn, I. Faud, C. E. Chee, K. -h. Yeh, P. -c. Lin, C. Chua, H. H. Hasbullah, M. A. Lee, A. Sharma, Y. Sun, G. Curigliano, H. Bando, F. Lordick, T. Yamanaka, J. Tabernero, E. Baba, A. Cervantes, A. Ohtsu, S. Peters, C. Ishioka, G. Pentheroudakis
Summary: The ESMO 2020 guidelines for localised colon cancer were adapted to account for ethnic differences in Asian patients during a special virtual meeting convened by ESMO and JSMO in March 2021. These guidelines represent the consensus opinions of experts from various oncological societies in Asia, and the voting was based on scientific evidence.
ANNALS OF ONCOLOGY
(2021)
Article
Oncology
T. Yoshino, A. Cervantes, H. Bando, E. Martinelli, E. Oki, R. -H. Xu, N. A. Mulansari, K. Govind Babu, M. A. Lee, C. K. Tan, G. Cornelio, D. Q. Chong, L. -T. Chen, S. Tanasanvimon, N. Prasongsook, K. -H. Yeh, C. Chua, M. D. Sacdalan, W. J. Sow (Jenson), S. T. Kim, R. T. Chacko, R. A. Syaiful, S. Z. Zhang, G. Curigliano, S. Mishima, Y. Nakamura, H. Ebi, Y. Sunakawa, M. Takahashi, E. Baba, S. Peters, C. Ishioka, G. Pentheroudakis
Summary: The ESMO Guidelines for metastatic colorectal cancer (mCRC) were adapted to produce the Pan-Asian adapted (PAGA) ESMO consensus guidelines for Asian patients. The guidelines were developed by a panel of experts from Asian oncological societies, based on scientific evidence and independent of treatment practices and reimbursement decisions. The aim is to optimize and harmonize the management of mCRC across Asia, considering the differences in screening practices, molecular profiling, and drug approvals and reimbursement strategies.
Article
Gastroenterology & Hepatology
Marianna V. Papageorge, Susanna W. L. de Geus, Jian Zheng, Alison P. Woods, Sing Chau Ng, Michael R. Cassidy, David McAneny, Jennifer F. Tseng, Teviah E. Sachs
Summary: This study revealed significant discordance between clinical and pathologic staging in resectable locally advanced gastric adenocarcinoma. Predictors of up-staging included younger age, male sex, poor tumor grade, positive margin status, and days from diagnosis to surgery. Patients who were up-staged had a lower survival rate compared to those who were accurately staged.
JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Review
Oncology
Kristin A. Higgins, Sonam Puri, Jhanelle E. Gray
Summary: The treatment of locally advanced non-small-cell lung cancer has undergone significant changes, with consolidative immunotherapy becoming the new standard of care. Despite improvements, further developments are needed for patients who experience disease progression after concurrent chemoradiation and immunotherapy, as well as those with driver mutations.
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Oncology
R. Kanesvaran, C. Porta, A. Wong, T. Powles, Q. S. Ng, M. Schmidinger, D. Ye, H. Malhotra, Y. Miura, J. L. Lee, F. L. T. Chong, Y-S Pu, C-C Yen, M. Saad, H. J. Lee, H. Kitamura, G. S. Bhattacharyya, G. Curigliano, E. Poon, S. P. Choo, S. Peters, E. Lim, T. Yoshino, G. Pentheroudakis
Summary: The ESMO and SSO held a special virtual guidelines meeting in May 2021 to adapt the 2019 guidelines for renal cell carcinoma treatment to account for ethnic differences in Asian patients. Expert opinions from oncological societies in China, India, Japan, Korea, Malaysia, Singapore, and Taiwan were considered based on scientific evidence independent of current treatment practices and drug access restrictions in Asian countries.
Review
Oncology
Anabela G. Barros, Catarina F. Pulido, Manuela Machado, Maria Jose Brito, Nuno Couto, Olga Sousa, Sonia A. Melo, Helder Mansinho
Summary: PDAC is a deadly malignant tumor with limited treatment options. Surgery is the only curative treatment, but many patients are diagnosed at a late stage. A multidisciplinary approach and molecular research are promising for future treatments.
INTERNATIONAL JOURNAL OF ONCOLOGY
(2021)
Article
Oncology
Marc W. Fromer, Jenci Hawthorne, Prejesh Philips, Michael E. Egger, Charles R. Scoggins, Kelly M. McMasters, Robert C. G. Martin
Summary: Pancreatic cancer is a complex malignancy, and with advancements in treatment techniques, more locally-advanced tumors are being successfully resected. Therefore, a new staging system has been proposed to better differentiate cases and guide treatment.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Leslie Y. Kam, Daniel Q. Huang, Alfred F. Tobias, Kitty Poon, Linda Henry, Paul Kwo, Ramsey Cheung, Mindie H. Nguyen
Summary: This study retrospectively analyzed the management of patients with chronic hepatitis B (CHB) under the assistance of advanced practice providers (APP) compared to physician-only care. The results showed that treatment-eligible patients with CHB receiving APP care were more likely to receive antiviral therapy. APP care may help to expand the pool of providers for patients with CHB, and to improve current suboptimal treatment rates.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
