Review
Radiology, Nuclear Medicine & Medical Imaging
Jung Jae Park, Chan Kyo Kim
Summary: This article reviews recent literature on the diagnostic value of pre-biopsy prostate MRI as a triage tool and discusses unresolved issues regarding the paradigm shift in the diagnosis of prostate cancer.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Silvia D. Chang, Sangeet Ghai, Chan Kyo Kim, Aytekin Oto, Francesco Giganti, Caroline M. Moore
Summary: Prostate cancer is the second most common malignancy in men worldwide. In recent years, MRI targeted biopsy has been found to detect more clinically significant cancer compared to systematic biopsy. The three common MRI targeted biopsy techniques have advantages and shortcomings, and studies to date have had mixed results on the preferred technique.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Oncology
Youdong Lin, Guihua Liu, Chun Liu, Hui Xie, Xiaoxian Wang, Yudian Huang, Long Jin, Huidan Chen
Summary: By incorporating urine urothelial carcinoembryonic antigen 1 (UCA1) gene expression levels and serum prostate-specific antigen (PSA) levels, the early detection and risk prediction of prostate cancer can be improved. The UCA1 score is superior to PSA alone in detecting and predicting the risk of prostate cancer, and the combination of PSA level and UCA1 score can significantly reduce the burden of prostate biopsy.
Article
Multidisciplinary Sciences
Kazushige Sakaguchi, Michikata Hayashida, Naoto Tanaka, Suguru Oka, Shinji Urakami
Summary: This study developed a risk model for detecting clinically significant prostate cancer (sPC) based on clinical parameters and bi-parametric magnetic resonance imaging (bpMRI) results in a Japanese cohort. The risk model, including age, log prostate-specific antigen, prostate volume, and PI-RADS scores, outperformed individual parameters alone in predicting sPC.
SCIENTIFIC REPORTS
(2021)
Review
Urology & Nephrology
M. Noureldin, D. Eldred-Evans, C. C. Khoo, M. Winkler, H. Sokhi, H. Tam, H. U. Ahmed
Summary: Traditionally, transrectal ultrasound (TRUS)-guided biopsy has been used in detecting prostate cancer, but alternative methods such as transperineal template biopsy are being explored. Current research is focused on refining biopsy techniques to maximize detection of significant cancers while minimizing risks and complications. MRI-targeted prostate biopsy has shown to be effective in detecting significant cancers and is an essential component in the diagnostic pathway of prostate cancer.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Richard C. Wu, Amir H. Lebastchi, Boris A. Hadaschik, Mark Emberton, Caroline Moore, Pilar Laguna, Jurgen J. Futterer, Arvin K. George
Summary: The use of multiparametric MRI in the diagnosis and management of prostate cancer has been accelerated and extensively discussed in the literature over the past decade. However, prostate cancer remains the only solid organ malignancy routinely diagnosed with random sampling.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Oncology
Matthew Parsons, Zoya Sandhu, Bridget Foy, Ernest Chan, Bryan Crawford, Libby Petersen, Benjamin Romney, Daniel Sommers, Jay Bishoff, Steven Lynch, Logan Mclean, David Gill
Summary: This study investigated the detection efficacy of MRI-guided fusion biopsy and systematic 12-core biopsy for MRI-visible prostate lesions. The results showed that MRI-guided fusion biopsy and systematic 12-core biopsy were consistent in detecting prostate cancer and clinically significant cancer, and combining both biopsies increased the detection rate of clinically significant cancer.
FRONTIERS IN ONCOLOGY
(2022)
Article
Urology & Nephrology
David Eldred-Evans, Martin J. Connor, Mariana Bertoncelli Tanaka, Edward Bass, Deepika Reddy, Uma Walters, Luke Stroman, Easter Espinosa, Raj Das, Nalin Khosla, Henry Tam, Elizabeth Pegers, Hasan Qazi, Stephen Gordon, Mathias Winkler, Hashim U. Ahmed
Summary: The RAPID prostate cancer diagnostic pathway allows 43% of men to avoid biopsy while accurately detecting clinically significant cancers and having a low detection rate for insignificant cancers. There are some variations among different centers.
Article
Health Care Sciences & Services
Pawel Rajwa, Nicolai A. Huebner, Dadjar I. Hostermann, Nico C. Grossmann, Victor M. Schuettfort, Stephan Korn, Fahad Quhal, Frederik Koenig, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Reza Sari Motlagh, Takafumi Yanagisawa, Abdulmajeed Aydh, Piotr Bryniarski, Benjamin Pradere, Andrzej Paradysz, Pascal A. Baltzer, Bernhard Grubmueller, Shahrokh F. Shariat
Summary: This study evaluated the predictive value of pre-biopsy blood-based markers in patients undergoing fusion biopsy for suspicious prostate MRI. It found that high dNLR and low PNI were associated with unfavorable biopsy outcomes, but most blood-based biomarkers did not significantly improve clinical decision-making.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Oncology
Xueqing Cheng, Jinshun Xu, Yuntian Chen, Zhenhua Liu, Guangxi Sun, Ling Yang, Jin Yao, Hao Zeng, Bin Song
Summary: TB alone had a higher detection rate of csPCa in the entire cohort, while SB alone had a higher detection rate of cisPCa. Additional SB only marginally increased the detection rate of csPCa compared to targeted biopsy, but significantly increased the detection rate of cisPCa. Stratification by PI-RADS category and prostate volume also showed similar results.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Xiaobin Wei, Li Zhu, Yanyan Zeng, Ke Xue, Yongming Dai, Jianrong Xu, Guiqin Liu, Fang Liu, Wei Xue, Dongmei Wu, Guangyu Wu
Summary: This study evaluated the performance of DR-CSI combined with SVM in detecting prostate cancer. The results showed that the DR-CSI model outperformed ADC and T-2 values in the exploration stage. The validation stage determined the requirements for mapping. In the test stage, DR-CSI showed higher diagnostic performance than PI-RADS and GE; 3 for both patients and lesions, as well as PI-RADS and GE; 4 for lesions. DR-CSI also had higher accuracy than PI-RADS and GE; 3 for clinically significant PCa.
Article
Radiology, Nuclear Medicine & Medical Imaging
Anwar R. R. Padhani, Ivo G. G. Schoots
Summary: This article comprehensively reviews the integration of MRI as a diagnostic tool in prostate cancer screening and provides practical recommendations for optimizing its use. To strike a balance between the benefits of early detection and minimizing harm, understanding the context of MRI use is crucial. Patient selection and MRI-targeted biopsies are key to optimization, along with screening-specific MRI protocols and accuracy levels. Automation, image quality monitoring, post-processing, radiologist certification, and deep-learning computer-aided software contribute to improved readings. The optimal utilization of MRI involves integrating it into a multi-step diagnostic pathway with quality-assured, cost-effective infrastructure ensuring community-wide access.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Byeongdo Song, Sung Il Hwang, Hak Jong Lee, Seong Jin Jeong, Sung Kyu Hong, Seok-Soo Byun, Sangchul Lee
Summary: This study compared the complications and pathological outcomes between TRUS-PB and MRI-TRUS FTPB, and found that MRI-TRUS FTPB is as safe as TRUS-PB in terms of complications. Additionally, the study showed that prostate volume is an important predictor of complications after prostate biopsy.
Article
Multidisciplinary Sciences
Linghui Liang, Feng Qi, Yifei Cheng, Lei Zhang, Dongliang Cao, Gong Cheng, Lixin Hua
Summary: This study analyzed the clinical characteristics of patients with negative bpMRI who did not require PBs, finding that some patients could safely avoid PB. Conversely, PB should be considered in patients with older age, suspicious DRE, significantly increased PSA value, significantly small PV on MRI, and PSAD>0.15 ng/ml/cm(3).
SCIENTIFIC REPORTS
(2021)
Article
Urology & Nephrology
Gabriele Sorce, Armando Stabile, Roberta Luciano, Giovanni Motterle, Simone Scuderi, Francesco Barletta, Francesco Pellegrino, Vito Cucchiara, Giorgio Gandaglia, Nicola Fossati, Francesco De Cobelli, Francesco Montorsi, R. Jeffrey Karnes, Ilaria Guccini, Alberto Briganti
Summary: This study found that mpMRI significantly underestimated the volume of the index lesion, especially for small visible lesions, regardless of the PI-RADS score. This should be taken into consideration when planning tailored focal therapy approaches, which are often delivered to men with smaller prostatic lesions.
Letter
Emergency Medicine
Hongxia Wang, Lili Chu, Dongze Li, Fating Zhou, Zhiyuan Wang, Guo Sui, Yi Zeng, Yu Cao
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Biochemical Research Methods
Wenya Hu, Qiong Pan, Yinghao Wang, Dongze Li, Yanfen Zhang, Honggang Nie, Yehua Han, Chang Samuel Hsu
Summary: This study developed a detailed analytical methodology to enhance the characterization of wood extractives at a molecular level. By selecting compatible solvent, evaluating ionization solvent, and using multi-dimensional data analysis, the complex compositions in wood extractives were comprehensively characterized. The extraction capability of seven solvents with varied polarities was examined and evaluated based on a large number of compounds. Various data-processing approaches were used to explore the chemodiversity of the extractives from different perspectives. This work greatly expanded the compound library of wood extractives and could guide the analysis of other biomass materials.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Oncology
Weiwei Yang, Jing Li, Minghui Zhang, Haichuan Yu, Yuan Zhuang, Lingyu Zhao, Lili Ren, Jinan Gong, Hongjie Bi, Lixuan Zeng, Yang Xue, Jinjin Yang, Yan Zhao, Shuoshuo Wang, Shuangshu Gao, Zitong Fu, Dongze Li, Jinxing Zhang, Tianzhen Wang, Ming Shan, Bo Tang, Xiaobo Li
Summary: This study aimed to evaluate the aberrant expression of 32 rhythm genes in breast cancer and found that NFIL3 promotes the proliferation and metastasis of TNBC cells. NFIL3 suppresses NFKBIA transcription, enhancing NF-kappa B signaling-mediated cancer-associated inflammation, and thereby promoting TNBC progression.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
(2022)
Article
Engineering, Electrical & Electronic
Jinwei Li, Bing Sun, Dongze Li, Qingzhen Xia, Jiawei Huang, Lei Wu, Hudong Chang, Rui Jia, Honggang Liu
Summary: This paper presents a K-band CMOS broadband low noise amplifier (LNA) based on the magnetically coupled resonator (MCR) matching network technique. The LNA consists of two common-source pseudo-differential stages, which use capacitive neutralization technique to enhance the inversion isolation and gain. The MCR-based input matching network achieves good balance and loss performance, improving the linearity and Noise Figure (NF) of the LNA.
IEICE ELECTRONICS EXPRESS
(2022)
Article
Multidisciplinary Sciences
Changbo Du, Dongze Li, Fu Yi, Laigui Wang, Ben Niu
Summary: This paper proposes a trilinear softening model for geotextile-reinforced tailings, which provides accurate numerical solutions through dimensionalization and finite difference methods. New interaction terms are introduced to analyze the interface characteristics, and a method is proposed for estimating the interface stiffness. The accuracy of the model is verified through comparison with experimental results.
Review
Medicine, General & Internal
Ling Zhu, Dongze Li, Xiao-Lian Jiang, Yu Jia, Yi Liu, Fanghui Li, Xiaoli Chen, Tao Lin, Dongmei Diao, Yongli Gao
Summary: This study aims to systematically evaluate and describe the impact of telemedicine interventions on essential hypertension. The study will include randomized controlled trials and assess primary outcomes (systolic and diastolic blood pressure) as well as secondary outcomes (medication adherence, quality of life, blood pressure control rate, and adverse events). The findings will be published in peer-reviewed journals through meta-analysis.
Article
Food Science & Technology
Ling Zhu, Fan Yang, Dongze Li, Gangcheng Wu, Hui Zhang
Summary: Pterostilbene (PTS) has received attention due to its health benefits, but its poor solubility limits its use in the food industry. This study prepared protein conjugates of PTS using whey protein isolate, soybean protein isolate, and flaxseed protein isolate, which improved its solubility and stability. The protein-based nano-complexes showed good stability and have potential applications in functional foods.
Article
Engineering, Electrical & Electronic
Yi You, Wei Wang, Dongze Li, Yu Jia, Dong Li, Rui Zeng, Lei Zhang
Summary: Electrocardiogram is a non-invasive method for diagnosing cardiovascular diseases. Deep neural networks are being increasingly utilized in electrocardiogram analysis, exhibiting higher efficiency and accuracy compared to traditional machine learning methods. While exercise electrocardiogram is useful in diagnosing ischemic heart disease, there is still limited research on its long-term predictive value.
ELECTRONICS LETTERS
(2023)
Article
Cardiac & Cardiovascular Systems
Yu Jia, Dongze Li, Jing Yu, Wenli Jiang, Yi Liu, Fanghui Li, Wentao Li, Rui Zeng, Xiaoyang Liao, Zhi Wan
Summary: This study aimed to investigate the relationship between plasma levels of IL-33, sST2, MPO, and MMP-9 and all-cause mortality in patients with AAD. The results showed that sST2, MPO, and MMP-9 were independently associated with mortality in patients with AAD, suggesting a pathogenic role for the IL-33/ST2/neutrophil granzyme system in these patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Nanoscience & Nanotechnology
Enhua Wang, Yidong Song, Jinlin Mei, Aocheng Wang, Dongze Li, Shanbin Gao, Lili Jin, Hui Shang, Aijun Duan, Xilong Wang
Summary: Hydrogenation of naphthalene can effectively reduce aromatic content in oil, and Pt-based aluminum-modified core-shell-structured nanoparticles showed excellent performance in this process. The synthesized Pt/Al-x-PMOs@MSNs catalysts exhibited preferable mass transfer and increased total acidity, leading to high conversion and selectivity of trans-decalin. The presence of sulfur had a temporary negative effect on naphthalene hydrogenation, but the catalysts ultimately recovered their original performance due to their unique texture and chemical properties.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Cardiac & Cardiovascular Systems
Lianjing Liang, Dongze Li, Rui Zeng, Haihong Zhang, Lin Lv, Wei Wei, Zhi Wan
Summary: This study evaluated the relationship between plasma ceramide levels and acute kidney injury (AKI) in patients with acute coronary syndrome (ACS). The study found that levels of certain ceramides were independently associated with AKI risk. These results suggest that long-chain and very-long-chain ceramide levels may help determine high AKI risk beyond traditional assessments.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Nursing
Haihong Zhang, Zhengli Luo, Dan Jia, Dongze Li, Yu Jia, Zhi Wan
INTERNATIONAL EMERGENCY NURSING
(2023)
Article
Geriatrics & Gerontology
Fanghui Li, Dongze Li, Jing Yu, Yu Jia, Jirui Wen, Wentao Li, Yao Tong, Jiang Wu, Zhi Wan, Yu Cao, Qing Zhang, Rui Zeng
Summary: This study found that the plasma lipidome profile at admission was associated with one-year mortality in patients with ACS. Measurements of long-chain ceramides and very-long-chain ceramides may help in identifying a high risk of mortality in ACS patients.
CLINICAL INTERVENTIONS IN AGING
(2023)
Article
Emergency Medicine
Tongyao Li, Yiwu Zhou, Dongze Li, Zhi Zeng, Shu Zhang
Summary: This study investigated the expression pattern of leukocyte long noncoding RNAs (lncRNAs) in patients with acute aortic dissection (AAD), and identified three potentially important diagnostic lncRNAs. The study also revealed the anti-inflammatory role of these lncRNAs in AAD and suggested ENST00000593848.1 as a promising candidate for further exploration as a diagnostic and prognostic factor.
Article
Chemistry, Multidisciplinary
Yuanyuan Yao, Dongze Li, Shaohua Jin, Zifeng Wang, Dongxu Wang, Qinghai Shu
Summary: In this study, MXene/NTO composites were synthesized, which effectively reduced the particle size of explosives and decreased their sensitivity to impact and friction. Additionally, MXene also improved the corrosion resistance and thermal stability of the composites, making them highly applicable in explosive technology.
NEW JOURNAL OF CHEMISTRY
(2022)
