CAR T-Cell Therapy: An Update for Radiologists

Diagnostic Performance of 18F-DCFPyL-PET/CT in Men with Biochemically Recurrent Prostate Cancer: Results from the CONDOR Phase 3, Multicenter Study

(2021) Michael J. Morris et al.   CLINICAL CANCER RESEARCH

Management of hemophagocytic lymphohistiocytosis (HLH) associated with chimeric antigen receptor T-cell (CAR-T) therapy using anti-cytokine therapy: an illustrative case and review of the literature

(2021) Ajay Major et al.   LEUKEMIA & LYMPHOMA

Early Evaluation of Immunotherapy Response in Lymphoma Patients by 18F-FDG PET/CT: A Literature Overview

(2021) Cristina Ferrari et al.   Journal of Personalized Medicine

Chimeric antigen receptor T-cell therapy for multiple myeloma

(2020) Naoki Hosen   INTERNATIONAL JOURNAL OF HEMATOLOGY

Progressive multifocal leukoencephalopathy after CAR T therapy

(2020) Konstantinos Sdrimas et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Invasive Pulmonary Aspergillosis

(2020) Marie-Pierre Ledoux et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

CD4/CD8 T-Cell Selection Affects Chimeric Antigen Receptor (CAR) T-Cell Potency and Toxicity: Updated Results From a Phase I Anti-CD22 CAR T-Cell Trial

(2020) Nirali N. Shah et al.   JOURNAL OF CLINICAL ONCOLOGY

Imaging the cancer immune environment and its response to pharmacological intervention- Part 1- The role of FDG PET/CT

(2020) Amir Iravani et al.   JOURNAL OF NUCLEAR MEDICINE

KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma

(2020) Michael Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diagnosis and Management of Secondary HLH/MAS Following HSCT and CAR-T Cell Therapy in Adults; A Review of the Literature and a Survey of Practice Within EBMT Centres on Behalf of the Autoimmune Diseases Working Party (ADWP) and Transplant Complications Working Party (TCWP)

(2020) Robert David Sandler et al.   Frontiers in Immunology

Hematopoietic recovery and immune reconstitution after axicabtagene ciloleucel in patients with large B-cell lymphoma

(2020) Paolo Strati et al.   HAEMATOLOGICA

Pseudoprogression during Immune Checkpoint Inhibitor Therapy for Solid Tumors: Clarity Amidst Rapid Evolution

(2020) Jonathan D. Dodd et al.   RADIOLOGY

High metabolic tumor volume is associated with decreased efficacy of axicabtagene ciloleucel in large B-cell lymphoma

(2020) Erin A. Dean et al.   Blood Advances

Side-effect management of chimeric antigen receptor (CAR) T-cell therapy.

(2020) M.-L. Schubert et al.   ANNALS OF ONCOLOGY

PET reporter gene imaging and ganciclovir-mediated ablation of chimeric antigen receptor T-cells in solid tumors

(2020) Surya Murty et al.   CANCER RESEARCH

Infections after anti-CD19 chimeric antigen receptor T-cell therapy for hematologic malignancies

(2020) Ghady Haidar et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Multifocal Necrotizing Leukoencephalopathy With Preferential Microglia Toxicity in a Patient Treated With Chimeric Antigen Receptor T-Cells and Review of the Literature

(2020) Daniel F Marker et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study

(2020) Jeremy S Abramson et al.   LANCET

Clinical and radiologic correlates of neurotoxicity after axicabtagene ciloleucel in large B-cell lymphoma

(2020) Paolo Strati et al.   Blood Advances

Prise en charge pratique du syndrome de relargage des cytokines (CRS) post-CAR-T cells chez l’adulte et l’enfant : recommandation de la Société francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)

(2019) Ibrahim Yakoub-Agha et al.   BULLETIN DU CANCER

PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)

(2019) Andrew G. Horti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CAR T-cell associated neurotoxicity: Mechanisms, clinicopathologic correlates, and future directions

(2019) Bradley D Hunter et al.   JNCI-Journal of the National Cancer Institute

Role of Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Predicting the Adverse Effects of Chimeric Antigen Receptor T Cell Therapy in Patients with Non-Hodgkin Lymphoma

(2019) Jiasheng Wang et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Evolution of chimeric antigen receptor (CAR) T cell therapy: current status and future perspectives

(2019) Young-Ho Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)–an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT)

(2019) Ankit J. Kansagra et al.   BONE MARROW TRANSPLANTATION

Imaging of CAR T-cells in cancer patients – paving the way to treatment monitoring and outcome prediction

(2019) Simone Krebs et al.   JOURNAL OF NUCLEAR MEDICINE

Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma

(2019) Noopur Raje et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed/refractory multiple myeloma

(2019) Jie Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CYTOKINE RELEASE SYNDROME AND NEUROTOXICITY BY BASELINE TUMOR BURDEN IN ADULTS WITH RELAPSED OR REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA TREATED WITH TISAGENLECLEUCEL

(2019) R.T. Maziarz et al.   HEMATOLOGICAL ONCOLOGY

Imaging CAR T cell therapy with PSMA-targeted positron emission tomography

(2019) Il Minn et al.   Science Advances

Hemophagocytic Lymphohistiocytosis: A Primer for Radiologists

(2019) Alice C. Shieh et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Haemophagocytic lymphohistiocytosis has variable time to onset following CD19 chimeric antigen receptor T cell therapy

(2019) Hamza Hashmi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Immune-related Adverse Events Associated With Checkpoint Inhibition in the Setting of CAR T Cell Therapy: A Case Series

(2019) Swetha Kambhampati et al.   Clinical Lymphoma Myeloma & Leukemia

Efficacy and Kinetics of CAR-T Cell Therapy in Children and Young Adults with Extramedullary Acute Lymphoblastic Leukemia (ALL) and Non-Hodgkin Lymphoma (NHL)

(2018) Bonnie Yates et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Cytokine Release Syndrome Grade as a Predictive Marker for Infections in Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia Treated With Chimeric Antigen Receptor T Cells

(2018) Jae H Park et al.   CLINICAL INFECTIOUS DISEASES

Management of the Critically Ill Adult Chimeric Antigen Receptor-T Cell Therapy Patient

(2018) Cristina Gutierrez et al.   CRITICAL CARE MEDICINE

T Cells Genetically Modified to Express an Anti–B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma

(2018) Jennifer N. Brudno et al.   JOURNAL OF CLINICAL ONCOLOGY

Immune-Modified Response Evaluation Criteria In Solid Tumors (imRECIST): Refining Guidelines to Assess the Clinical Benefit of Cancer Immunotherapy

(2018) F. Stephen Hodi et al.   JOURNAL OF CLINICAL ONCOLOGY

Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel

(2018) David Porter et al.   Journal of Hematology & Oncology

Positron emission tomography of adoptively transferred chimeric antigen receptor T cells with Zirconium-89 oxine

(2018) Michael Ryan Weist et al.   JOURNAL OF NUCLEAR MEDICINE

Pleural cavity cytokine release syndrome in CD19-directed chimeric antigen receptor-modified T cell therapy

(2018) Lijuan Ding et al.   MEDICINE

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

(2018) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell‐Induced Severe or Life‐Threatening Cytokine Release Syndrome

(2018) Robert Q. Le et al.   ONCOLOGIST

Clinical and Biologic Correlates of Neurotoxicity Associated with CAR T Cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia (B-ALL)

(2018) Bianca D. Santomasso et al.   Cancer Discovery

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

ASBMT Consensus Grading for Cytokine Release Syndrome and Neurological Toxicity Associated with Immune Effector Cells

(2018) Daniel W Lee et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Recent advances in CAR T-cell toxicity: Mechanisms, manifestations and management

(2018) Jennifer N. Brudno et al.   BLOOD REVIEWS

Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies

(2018) Juliane Gust et al.   CNS DRUGS

Early positron emission tomography/computed tomography as a predictor of response after CTL019 chimeric antigen receptor –T-cell therapy in B-cell non-Hodgkin lymphomas

(2018) Nirav N. Shah et al.   CYTOTHERAPY

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial

(2018) Frederick L Locke et al.   LANCET ONCOLOGY

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma

(2018) Stephen J. Schuster et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric antigen receptor T-cell therapy — assessment and management of toxicities

(2017) Sattva S. Neelapu et al.   Nature Reviews Clinical Oncology

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

(2017) Sattva S. Neelapu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma

(2017) Khun Visith Keu et al.   Science Translational Medicine

Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells

(2017) Juliane Gust et al.   Cancer Discovery

T cells expressing an anti-B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma

(2016) S. A. Ali et al.   BLOOD

Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography

(2016) Amer M. Najjar et al.   MOLECULAR IMAGING AND BIOLOGY

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

(2010) Richard A Morgan et al.   MOLECULAR THERAPY

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER

Noninvasive detection of therapeutic cytolytic T cells with 18F–FHBG PET in a patient with glioma

(2008) Shahriar S Yaghoubi et al.   Nature clinical practice. Oncology