Sexual dimorphic impact of adult‐onset somatopause on life span and age‐induced osteoarthritis

Osteoarthritis

(2019) David J Hunter et al.   LANCET

Naturally occurring osteoarthritis in male mice with an extended lifespan

(2019) Dave Ewart et al.   CONNECTIVE TISSUE RESEARCH

The enigmatic role of growth hormone in age-related diseases, cognition, and longevity

(2019) Gabriela Colon et al.   GeroScience

NLRP3 as a potentially novel biomarker for the management of osteoarthritis

(2018) M.J. McAllister et al.   OSTEOARTHRITIS AND CARTILAGE

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

(2017) Rigo Cintron-Colon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex Differences in Lifespan

(2016) Steven N. Austad et al.   Cell Metabolism

Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females

(2016) Riia K. Junnila et al.   ENDOCRINOLOGY

Ageing and the pathogenesis of osteoarthritis

(2016) Richard F. Loeser et al.   Nature Reviews Rheumatology

Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

(2016) Olga Spadaro et al.   Cell Reports

Long- But Not Short-Term Adult-Onset, Isolated GH Deficiency in Male Mice Leads to Deterioration of β-Cell Function, Which Cannot Be Accounted for by Changes in β-Cell Mass

(2014) Jose Cordoba-Chacon et al.   ENDOCRINOLOGY

Ephrin B2/EphB4 Mediates the Actions of IGF-I Signaling in Regulating Endochondral Bone Formation

(2014) Yongmei Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Longevity effect of IGF-1R+/−mutation depends on genetic background-specific receptor activation

(2013) Jie Xu et al.   AGING CELL

Synovial perlecan is required for osteophyte formation in knee osteoarthritis

(2013) Haruka Kaneko et al.   MATRIX BIOLOGY

Effects of aging on articular cartilage homeostasis

(2012) Martin Lotz et al.   BONE

The Rise in Growth Hormone during Starvation Does Not Serve to Maintain Glucose Levels or Lean Mass but Is Required for Appropriate Adipose Tissue Response in Female Mice

(2012) Manuel D. Gahete et al.   ENDOCRINOLOGY

A longer interval without GH replacement and female gender are associated with lower bone mineral density in adults with childhood-onset GH deficiency: a KIMS database analysis

(2012) Nicholas A Tritos et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Fifteen years of GH replacement increases bone mineral density in hypopituitary patients with adult-onset GH deficiency

(2012) M. Elbornsson et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Histopathology of naturally occurring and surgically induced osteoarthritis in mice

(2012) M.A. McNulty et al.   OSTEOARTHRITIS AND CARTILAGE

Metabolic Impact of Adult-Onset, Isolated, Growth Hormone Deficiency (AOiGHD) Due to Destruction of Pituitary Somatotropes

(2011) Raul M. Luque et al.   PLoS One

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

A Comprehensive Histological Assessment of Osteoarthritis Lesions in Mice

(2011) Margaret A. McNulty et al.   Cartilage

GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients

(2010) Simon Doessing et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Additive Effects of Intra-articular Injection of Growth Hormone and Hyaluronic Acid in Rabbit Model of Collagenase-induced Osteoarthritis

(2010) Sang Beom Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice

(2009) Y. Ikeno et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Considerations on Temperature, Longevity and Aging

(2008) B. Conti   CELLULAR AND MOLECULAR LIFE SCIENCES

The Effect of Growth Hormone Replacement on Exercise Capacity in Patients with GH Deficiency: A Metaanalysis

(2008) W. Matthew Widdowson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM