A review of the physiological impact of rare earth elements and their uses in biomedical Mg alloys

Biodegradable magnesium alloy (WE43) in bone‐fixation plate and screw

(2020) Soo‐Hwan Byun et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

A lean magnesium–zinc–calcium alloy ZX00 used for bone fracture stabilization in a large growing-animal model

(2020) Patrick Holweg et al.   Acta Biomaterialia

A lean bioabsorbable magnesium-zinc-calcium alloy ZX00 used for operative treatment of medial malleolus fractures

(2020) Patrick Holweg et al.   Bone & Joint Research

Magnesium-Based Resorbable Scaffold versus Permanent Metallic Sirolimus-Eluting Stent in Patients with ST-Segment Elevation Myocardial Infarction: The MAGSTEMI Randomized Clinical Trial

(2019) Manel Sabaté et al.   CIRCULATION

Comparative in vitro study on binary Mg-RE (Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu) alloy systems

(2019) Jianing Liu et al.   Acta Biomaterialia

Comparison of clinical outcomes between Magmaris and Orsiro drug eluting stent at 12 months: Pooled patient level analysis from BIOSOLVE II–III and BIOFLOW II trials

(2019) Alexandre Hideo-Kajita et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mechanical, corrosion, and biocompatibility properties of Mg-Zr-Sr-Sc alloys for biodegradable implant applications

(2019) Khurram Munir et al.   Acta Biomaterialia

The degradation and transport mechanism of a Mg-Nd-Zn-Zr stent in rabbit common carotid artery: A 20-month study

(2018) Jian Zhang et al.   Acta Biomaterialia

Fixation of medial malleolar fractures with magnesium bioabsorbable headless compression screws: short-term clinical and radiological outcomes in eleven patients

(2018) Ozkan Kose et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

The era of biofunctional biomaterials in orthopedics: what does the future hold?

(2018) Mubashar Rehman et al.   Expert Review of Medical Devices

Lanthanum chloride impairs memory in rats by disturbing the glutamate-glutamine cycle and over-activating NMDA receptors

(2018) Xiaoyu Hu et al.   FOOD AND CHEMICAL TOXICOLOGY

COMPARISON OF CLINICAL OUTCOMES BETWEEN MAGMARIS (DREAMS 2G) AND ORSIRO DRUG ELUTING STENTS: POOLED PATIENT LEVEL ANALYSIS FROM BIOSOLVE II-III AND BIOFLOW II TRIALS

(2018) Alexandre Hideo-Kajita et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effects of scandium addition on biocompatibility of biodegradable Mg–1.5Zn–0.6Zr alloy

(2018) Tao Li et al.   MATERIALS LETTERS

Comparison of a resorbable magnesium implant in small and large growing-animal models

(2018) N.G. Grün et al.   Acta Biomaterialia

Safety and clinical performance of a drug eluting absorbable metal scaffold in the treatment of subjects with de novo lesions in native coronary arteries: Pooled 12-month outcomes of BIOSOLVE-II and BIOSOLVE-III

(2018) Michael Haude et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Response of the freshwater mussel, Dreissena polymorpha to sub-lethal concentrations of samarium and yttrium after chronic exposure

(2018) Houda Hanana et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

TCT-350 Safety and Performance of the Resorbable Magnesium Scaffold, Magmaris in a Real World Setting - First 400 Subjects at 12-month Follow-up of the BIOSOLVE-IV Registry

(2018) Michael Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nephrotoxicity of gadolinium-based contrast in the setting of renal artery intervention: retrospective analysis with 10-year follow-up

(2018) Edwin A. Takahashi et al.   Diagnostic and Interventional Radiology

Mechanical properties, corrosion, and biocompatibility of Mg-Zr-Sr-Dy alloys for biodegradable implant applications

(2017) Yunfei Ding et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Biocompatibility and degradation properties of WE43 Mg alloys with and without heat treatment: In vivo evaluation and comparison in a cranial bone sheep model

(2017) Andrea Torroni et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Magmaris: a new generation metallic sirolimus-eluting fully bioresorbable scaffold: present status and future perspectives

(2017) Claudio Rapetto et al.   Journal of Thoracic Disease

Six cas de série de patients de Magnezix ® . Une vis métallique absorbable pour la fixation de la fracture du carpe et des fusions entre les carpes

(2017) Philip Grieve et al.   Hand Surgery & Rehabilitation

Long-term in vivo degradation behavior and near-implant distribution of resorbed elements for magnesium alloys WZ21 and ZX50

(2016) F. Amerstorfer et al.   Acta Biomaterialia

Design of magnesium alloys with controllable degradation for biomedical implants: From bulk to surface

(2016) Xia Li et al.   Acta Biomaterialia

The in vivo degradation and bone-implant interface of Mg-Nd-Zn-Zr alloy screws: 18 months post-operation results

(2016) Jialin Niu et al.   CORROSION SCIENCE

Magnesium alloys: A stony pathway from intensive research to clinical reality. Different test methods and approval-related considerations

(2016) Elmar Willbold et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

In vivo degradation of magnesium plate/screw osteosynthesis implant systems: Soft and hard tissue response in a calvarial model in miniature pigs

(2016) Benoit Schaller et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Safety and performance of the second-generation drug-eluting absorbable metal scaffold in patients with de-novo coronary artery lesions (BIOSOLVE-II): 6 month results of a prospective, multicentre, non-randomised, first-in-man trial

(2016) Michael Haude et al.   LANCET

Lanthanum nitrate genotoxicity evaluation: Ames test, mouse micronucleus assay, and chromosome aberration test

(2016) Hui Yang et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Long-term clinical study and multiscale analysis of in vivo biodegradation mechanism of Mg alloy

(2016) Jee-Wook Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical properties, in vitro corrosion and biocompatibility of newly developed biodegradable Mg-Zr-Sr-Ho alloys for biomedical applications

(2016) Yunfei Ding et al.   Scientific Reports

Effect of the addition of low rare earth elements (lanthanum, neodymium, cerium) on the biodegradation and biocompatibility of magnesium

(2015) Elmar Willbold et al.   Acta Biomaterialia

In vivo evaluation of a magnesium-based degradable intramedullary nailing system in a sheep model

(2015) Christina Rössig et al.   Acta Biomaterialia

Enhanced antibacterial properties, biocompatibility, and corrosion resistance of degradable Mg-Nd-Zn-Zr alloy

(2015) Hui Qin et al.   BIOMATERIALS

Health effects and toxicity mechanisms of rare earth elements—Knowledge gaps and research prospects

(2015) Giovanni Pagano et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements

(2015) Djordje Antonijevic et al.   JOURNAL OF ENDODONTICS

Cellular response to rare earth mixtures (La and Gd) as components of degradable Mg alloys for medical applications

(2014) Claudia A. Grillo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Corrosion of magnesium alloys: the role of alloying

(2014) K. Gusieva et al.   INTERNATIONAL MATERIALS REVIEWS

Immunological Response to Biodegradable Magnesium Implants

(2014) Karin Pichler et al.   JOM

Genotoxicity analysis of cerium oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral administration

(2014) M. Kumari et al.   MUTAGENESIS

Effects of alloying elements on the corrosion behavior and biocompatibility of biodegradable magnesium alloys: a review

(2014) Yunfei Ding et al.   Journal of Materials Chemistry B

In vitro and in vivo corrosion, cytocompatibility and mechanical properties of biodegradable Mg–Y–Ca–Zr alloys as implant materials

(2013) Da-Tren Chou et al.   Acta Biomaterialia

In vitro and in vivo evaluation of biodegradable, open-porous scaffolds made of sintered magnesium W4 short fibres

(2013) K. Bobe et al.   Acta Biomaterialia

Biodegradable magnesium-based screw clinically equivalent to titanium screw in hallux valgus surgery: short term results of the first prospective, randomized, controlled clinical pilot study

(2013) Henning Windhagen et al.   Biomedical Engineering Online

Degrading magnesium screws ZEK100: biomechanical testing, degradation analysis and soft-tissue biocompatibility in a rabbit model

(2013) Janin Reifenrath et al.   Biomedical Materials

In vivo testing of a bioabsorbable magnesium alloy serving as total ossicular replacement prostheses

(2013) Rebecca Lensing et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

In vivo study of a biodegradable orthopedic screw (MgYREZr-alloy) in a rabbit model for up to 12 months

(2013) Hazibullah Waizy et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

A Comparison of Corrosion Behavior in Saline Environment: Rare Earth Metals (Y, Nd, Gd, Dy) for Alloying of Biodegradable Magnesium Alloys

(2013) Xu Zhao et al.   JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY

Safety and performance of the drug-eluting absorbable metal scaffold (DREAMS) in patients with de-novo coronary lesions: 12 month results of the prospective, multicentre, first-in-man BIOSOLVE-I trial

(2013) Michael Haude et al.   LANCET

Influence of the grain size on the in vivo degradation behaviour of the magnesium alloy LAE442

(2013) Berit Ullmann et al.   PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

Accumulation of Scandium in Plasma in Patients with Chronic Renal Failure

(2013) Cristina Sánchez-González et al.   TheScientificWorldJOURNAL

Effect of a plasmaelectrolytic coating on the strength retention of in vivo and in vitro degraded magnesium implants

(2012) T. Imwinkelried et al.   Acta Biomaterialia

Long-term in vivo degradation behaviour and biocompatibility of the magnesium alloy ZEK100 for use as a biodegradable bone implant

(2012) Dina Dziuba et al.   Acta Biomaterialia

Microstructure, mechanical properties, biocorrosion behavior, and cytotoxicity of as-extruded Mg–Nd–Zn–Zr alloy with different extrusion ratios

(2012) Xiaobo Zhang et al.   Journal of the Mechanical Behavior of Biomedical Materials

Magnesium alloys for temporary implants in osteosynthesis: In vivo studies of their degradation and interaction with bone

(2011) Tanja Kraus et al.   Acta Biomaterialia

Organ Histopathological Changes and its Function Damage in Mice Following Long-term Exposure to Lanthanides Chloride

(2011) Jie Cheng et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Fibroblast Response to Lanthanoid Metal Ion Stimulation: Potential Contribution to Fibrotic Tissue Injury

(2011) William Jenkins et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Genotoxic effects of aluminum, iron and manganese in human cells and experimental systems: A review of the literature

(2011) PDL Lima et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Differential genotoxicity of chemical properties and particle size of rare metal and metal oxide nanoparticles

(2011) Go Hasegawa et al.   JOURNAL OF APPLIED TOXICOLOGY

Effects of extrusion and heat treatment on the mechanical properties and biocorrosion behaviors of a Mg–Nd–Zn–Zr alloy

(2011) Xiaobo Zhang et al.   Journal of the Mechanical Behavior of Biomedical Materials

Biocorrosion properties of as-extruded Mg–Nd–Zn–Zr alloy compared with commercial AZ31 and WE43 alloys

(2011) Xiaobo Zhang et al.   MATERIALS LETTERS

In Vivo Degradation Behavior of the Magnesium Alloy LANd442 in Rabbit Tibiae

(2011) Berit Ullmann et al.   Materials

In Vivo Corrosion of Two Novel Magnesium Alloys ZEK100 and AX30 and Their Mechanical Suitability as Biodegradable Implants

(2011) Tim Andreas Huehnerschulte et al.   Materials

Comparative cytotoxicity evaluation of lanthanide nanomaterials on mouse and human cell lines with metabolic and DNA-quantification assays

(2010) Boon Chin Heng et al.   Biointerphases

The Effect of Ketoconazole on Candida albicans Infection Following Depression of the Retidoendothelial Activity with Gadolinium Chloride: Wirkung von Ketoconazol auf Candida albicans-Infektion bei Gadolinium Chloride-deprimierter reticuloendothelialer Akt

(2010) Beatrix Farkas et al.   MYCOSES

Magnesium Supplementation and Osteoporosis

(2010) J. E. Sojka   NUTRITION REVIEWS

Assessment of embryotoxicity of compounds in cosmetics by the embryonic stem cell test

(2010) Rui Chen et al.   TOXICOLOGY MECHANISMS AND METHODS

In vivo corrosion and corrosion protection of magnesium alloy LAE442☆

(2009) F. Witte et al.   Acta Biomaterialia

On the in vitro and in vivo degradation performance and biological response of new biodegradable Mg–Y–Zn alloys☆

(2009) Anja C. Hänzi et al.   Acta Biomaterialia

Evaluation of short-term effects of rare earth and other elements used in magnesium alloys on primary cells and cell lines☆

(2009) Frank Feyerabend et al.   Acta Biomaterialia

Efficacy and safety of lanthanoids as X-ray contrast agents

(2009) Hubertus Pietsch et al.   EUROPEAN JOURNAL OF RADIOLOGY

Early- and Long-Term Intravascular Ultrasound and Angiographic Findings After Bioabsorbable Magnesium Stent Implantation in Human Coronary Arteries

(2009) Ron Waksman et al.   JACC-Cardiovascular Interventions

Degradation behaviour and mechanical properties of magnesium implants in rabbit tibiae

(2009) Annett Krause et al.   JOURNAL OF MATERIALS SCIENCE

Rare earth metals used in biodegradable magnesium-based stents do not interfere with proliferation of smooth muscle cells but do induce the upregulation of inflammatory genes

(2008) Andreas Drynda et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Dy3+ and Nd3+ induced genetic mutation of bacillus α-amylase

(2008) Dongyan Zhang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Acute effects on the lung and the liver of oral administration of cerium chloride on adult, neonatal and fetal mice

(2007) Masami Kawagoe et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY