Journal
ACS CHEMICAL NEUROSCIENCE
Volume 12, Issue 18, Pages 3284-3287Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acschemneuro.1c00526
Keywords
Sugar consumption; flavored alcoholic beverages; alcohol drinking; brain penetrant sugars; alcohol use disorder; central nervous system
Funding
- Rural Drug Addiction Research (RDAR) Center (COBRE) [P20GM130461]
- IMARI (Increasing Minority Admissions to Research Institutions) research program [1R25GM106994-01]
- Nebraska Tobacco Settlement Biochemical Research Funds
- [GM130461]
- [DA046109]
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It is important for basic researchers to consider how the sugars mixed with alcoholic beverages may impact the neurochemical and biological mechanisms influencing alcohol drinking and the development of alcohol use disorder. Commercially available flavored alcoholic beverages are typically sweetened with some kind of sugar, which may potentiate drinking by making the alcohol taste better, especially for adolescents.
While sugar consumption and alcohol drinking have traditionally been studied by different basic science fields, most commercially available flavored alcoholic beverages are sweetened with some kind of sugar. The prevailing view is that these sugars potentiate drinking by making the alcohol taste better, particularly for adolescents, overlooking that some central nervous system circuits implicated in alcohol drinking are also sensitive to brain penetrant sugars like glucose. In this Viewpoint, we highlight the need for basic researchers to carefully consider how the sugars mixed with alcoholic beverages may impact the neurochemical and biological mechanisms influencing alcohol drinking and the development of alcohol use disorder.
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