Microneedle Arrays for Sampling and Sensing Skin Interstitial Fluid

Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

(2021) Zheyu Wang et al.   Nature Biomedical Engineering

Lab under the Skin: Microneedle Based Wearable Devices

(2021) Hazhir Teymourian et al.   Advanced Healthcare Materials

One-Shot Fabrication of Polymeric Hollow Microneedles by Standard Photolithography

(2021) Principia Dardano et al.   Polymers

Gelatin Methacryloyl Microneedle Patches for Minimally Invasive Extraction of Skin Interstitial Fluid

(2020) Jixiang Zhu et al.   Small

Engineering Microneedles for Therapy and Diagnosis: A Survey

(2020) Liping Xie et al.   Micromachines

Osmosis‐Powered Hydrogel Microneedles for Microliters of Skin Interstitial Fluid Extraction within Minutes

(2020) Mengjia Zheng et al.   Advanced Healthcare Materials

Surface Enhanced Raman Spectroscopy Based Biosensor with a Microneedle Array for Minimally Invasive In Vivo Glucose Measurements

(2020) Jian Ju et al.   ACS Sensors

An Interface–Particle Interaction Approach for Evaluation of the Co-Encapsulation Efficiency of Cells in a Flow-Focusing Droplet Generator

(2020) Mohammad Yaghoobi et al.   SENSORS

A microfluidic concentration gradient generator for simultaneous delivery of two reagents on a millimeter-sized sample

(2020) Milad Rismanian et al.   Journal of Flow Chemistry

RhoA and Rac1 in Liver Cancer Cells: Induction of Overexpression Using Mechanical Stimulation

(2020) Sharda Yadav et al.   Micromachines

PCR-Free Detection of Long Non-Coding HOTAIR RNA in Ovarian Cancer Cell Lines and Plasma Samples

(2020) Narshone Soda et al.   Cancers

Swellable Gelatin Methacryloyl Microneedles for Extraction of Interstitial Skin Fluid toward Minimally Invasive Monitoring of Urea

(2020) Daniela F. S. Fonseca et al.   MACROMOLECULAR BIOSCIENCE

Magnetofluidic spreading in circular chambers under a uniform magnetic field

(2020) Mohammad Amin Maleki et al.   Microfluidics and Nanofluidics

Sampling interstitial fluid from human skin using a microneedle patch

(2020) Pradnya P. Samant et al.   Science Translational Medicine

3D-printed microneedles in biomedical applications

(2020) Sajjad Rahmani Dabbagh et al.   iScience

Microneedle-assisted technology for minimally invasive medical sensing

(2020) Bao Li Zhang et al.   MICROCHEMICAL JOURNAL

Microneedle based electrochemical (Bio)Sensing: Towards decentralized and continuous health status monitoring

(2020) Juan José García-Guzmán et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Minimally-invasive Microneedle-based Biosensor Array for Simultaneous Lactate and Glucose Monitoring in Artificial Interstitial Fluid

(2019) Paolo Bollella et al.   ELECTROANALYSIS

Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch

(2019) Chandana Kolluru et al.   Advanced Healthcare Materials

Effects of magnetic nanoparticles on mixing in droplet-based microfluidics

(2019) Mohammad Amin Maleki et al.   PHYSICS OF FLUIDS

Fabrication of microporous inorganic microneedles by centrifugal casting method for transdermal extraction and delivery

(2019) Samira Gholami et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Monitoring drug pharmacokinetics and immunologic biomarkers in dermal interstitial fluid using a microneedle patch

(2019) Chandana Kolluru et al.   BIOMEDICAL MICRODEVICES

Stretching cells – An approach for early cancer diagnosis

(2019) Sharda Yadav et al.   EXPERIMENTAL CELL RESEARCH

Simple, Cost-Effective, and Continuous 3D Dielectrophoretic Microchip for Concentration and Separation of Bioparticles

(2019) Parham Tajik et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Design of composite microneedle sensor systems for the measurement of transdermal pH

(2019) Catherine Hegarty et al.   MATERIALS CHEMISTRY AND PHYSICS

Gold microneedles fabricated by casting of gold ink used for urea sensing

(2019) Mehmet Senel et al.   MATERIALS LETTERS

Plasmonic paper microneedle patch for on-patch detection of molecules in dermal interstitial fluid

(2019) CHANDANA KOLLURU et al.   ACS Sensors

Development of a Minimally Invasive Microneedle-Based Sensor for Continuous Monitoring of β-Lactam Antibiotic Concentrations in Vivo

(2019) Sally A. N. Gowers et al.   ACS Sensors

Encoded Microneedle Arrays for Detection of Skin Interstitial Fluid Biomarkers

(2019) Xiaoxuan Zhang et al.   ADVANCED MATERIALS

Fabrication of sponge-forming microneedle patch for rapidly sampling interstitial fluid for analysis

(2019) Jianmin Chen et al.   BIOMEDICAL MICRODEVICES

Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid

(2019) Paolo Bollella et al.   Catalysts

Electrochemically Controlled Dissolution of Nanocarbon–Cellulose Acetate Phthalate Microneedle Arrays

(2019) Ashleigh Anderson et al.   ACS Applied Materials & Interfaces

Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid

(2019) Dana Al Sulaiman et al.   ACS Nano

Lipid profiling of suction blister fluid: comparison of lipids in interstitial fluid and plasma

(2019) Anders K. Nilsson et al.   Lipids in Health and Disease

Plasmonic Microneedle Arrays for in Situ Sensing with Surface-Enhanced Raman Spectroscopy (SERS)

(2019) Ji Eun Park et al.   NANO LETTERS

Three-Dimensional Modeling of Avascular Tumor Growth in Both Static and Dynamic Culture Platforms

(2019) Ali Taghibakhshi et al.   Micromachines

Wearable Electrochemical Microneedle Sensor for Continuous Monitoring of Levodopa: Toward Parkinson Management

(2019) K. Yugender Goud et al.   ACS Sensors

Rapid Softlithography Using 3D‐Printed Molds

(2019) Sajad Razavi Bazaz et al.   Advanced Materials Technologies

In Situ Sampling and Monitoring Cell-Free DNA of the Epstein–Barr Virus from Dermal Interstitial Fluid Using Wearable Microneedle Patches

(2019) Bin Yang et al.   ACS Applied Materials & Interfaces

Biocompatible 3D Printed Microneedles for Transdermal, Intradermal, and Percutaneous Applications

(2019) Khalil Moussi et al.   ADVANCED ENGINEERING MATERIALS

Microneedle-Based Detection of Ketone Bodies along with Glucose and Lactate: Toward Real-Time Continuous Interstitial Fluid Monitoring of Diabetic Ketosis and Ketoacidosis

(2019) Hazhir Teymourian et al.   ANALYTICAL CHEMISTRY

A tool for designing tree-like concentration gradient generators for lab-on-a-chip applications

(2019) Milad Ebadi et al.   CHEMICAL ENGINEERING SCIENCE

3D Printed Multi-Functional Hydrogel Microneedles Based on High-Precision Digital Light Processing

(2019) Wei Yao et al.   Micromachines

Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics

(2018) Megan M. Niedzwiecki et al.   ANALYTICAL CHEMISTRY

Rapid and selective sampling of IgG from skin in less than 1 min using a high surface area wearable immunoassay patch

(2018) Jacob W. Coffey et al.   BIOMATERIALS

Recent advances and current challenges in magnetophoresis based micro magnetofluidics

(2018) Ahmed Munaz et al.   Biomicrofluidics

Organ/body-on-a-chip based on microfluidic technology for drug discovery

(2018) Hiroshi Kimura et al.   Drug Metabolism and Pharmacokinetics

Rapid paper based colorimetric detection of glucose using a hollow microneedle device

(2018) Dean Nicholas et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Full-thickness human skin-on-chip with enhanced epidermal morphogenesis and barrier function

(2018) Gopu Sriram et al.   Materials Today

Nonenzymatic determination of glucose at near neutral pH values based on the use of nafion and platinum black coated microneedle electrode array

(2018) Somasekhar R. Chinnadayyala et al.   MICROCHIMICA ACTA

Mechanisms of sampling interstitial fluid from skin using a microneedle patch

(2018) Pradnya P. Samant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Flexible Interdigital Electrode Used in Skin Penetration Promotion and Evaluation with Electroporation and Reverse Iontophoresis Synergistically

(2018) Rongjian Zhao et al.   SENSORS

Wearable non-invasive epidermal glucose sensors: A review

(2018) Jayoung Kim et al.   TALANTA

Wearable Wireless Tyrosinase Bandage and Microneedle Sensors: Toward Melanoma Screening

(2018) Bianca Ciui et al.   Advanced Healthcare Materials

Uniform sensing layer of immiscible enzyme-mediator compounds developed via a spray aerosol mixing technique towards low cost minimally invasive microneedle continuous glucose monitoring devices

(2018) Siamak Samavat et al.   BIOSENSORS & BIOELECTRONICS

Microneedle-based biosensor for minimally-invasive lactate detection

(2018) Paolo Bollella et al.   BIOSENSORS & BIOELECTRONICS

Magnetophoretic separation of diamagnetic particles through parallel ferrofluid streams

(2018) Ahmed Munaz et al.   SENSORS AND ACTUATORS B-CHEMICAL

Simultaneous Monitoring of Sweat and Interstitial Fluid Using a Single Wearable Biosensor Platform

(2018) Jayoung Kim et al.   Advanced Science

Differences in biocompatibility of microneedles from cyclic olefin polymers with human endothelial and epithelial skin cells

(2018) Klaudia Schossleitner et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Cell and fluid sampling microneedle patches for monitoring skin-resident immunity

(2018) Anasuya Mandal et al.   Science Translational Medicine

Microfluidics for Porous Systems: Fabrication, Microscopy and Applications

(2018) Alireza Gerami et al.   TRANSPORT IN POROUS MEDIA

Proteomic Characterization of Dermal Interstitial Fluid Extracted Using a Novel Microneedle-Assisted Technique

(2017) Bao Quoc Tran et al.   JOURNAL OF PROTEOME RESEARCH

Numerical Simulation of the Behavior of Toroidal and Spheroidal Multicellular Aggregates in Microfluidic Devices with Microwell and U-Shaped Barrier

(2017) Maryam Barisam et al.   Micromachines

Epidermal Microfluidic Electrochemical Detection System: Enhanced Sweat Sampling and Metabolite Detection

(2017) Aida Martín et al.   ACS Sensors

Wearable/disposable sweat-based glucose monitoring device with multistage transdermal drug delivery module

(2017) Hyunjae Lee et al.   Science Advances

Epidermal Tattoo Patch for Ultrasound-Based Transdermal Microballistic Delivery

(2017) Fernando Soto et al.   Advanced Materials Technologies

Evaluation of a minimally invasive glucose biosensor for continuous tissue monitoring

(2016) Sanjiv Sharma et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dynamic application of microprojection arrays to skin induces circulating protein extravasation for enhanced biomarker capture and detection

(2016) Jacob W. Coffey et al.   BIOMATERIALS

A continuous glucose monitoring device by graphene modified electrochemical sensor in microfluidic system

(2016) Zhihua Pu et al.   Biomicrofluidics

Transdermal microneedle sensor arrays based on palladium: Polymer composites

(2016) Aaron McConville et al.   ELECTROCHEMISTRY COMMUNICATIONS

Hydrogel-forming microneedle arrays: Potential for use in minimally-invasive lithium monitoring

(2016) Eyman Eltayib et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Therapeutic Drug Monitoring of Vancomycin in Dermal Interstitial Fluid Using Dissolving Microneedles

(2016) Yukako Ito et al.   International Journal of Medical Sciences

A lab-on-a-chip device for investigating the fusion process of olfactory ensheathing cell spheroids

(2016) Ahmed Munaz et al.   LAB ON A CHIP

Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

(2016) Eneko Larrañeta et al.   MATERIALS SCIENCE & ENGINEERING R-REPORTS

Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer

(2016) Ann Rita Halvorsen et al.   Molecular Oncology

A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy

(2016) Hyunjae Lee et al.   Nature Nanotechnology

Polymeric microneedles based enzymatic electrodes for electrochemical biosensing of glucose and lactic acid

(2016) A. Caliò et al.   SENSORS AND ACTUATORS B-CHEMICAL

A patch type non-enzymatic biosensor based on 3D SUS micro-needle electrode array for minimally invasive continuous glucose monitoring

(2016) Su Jin Lee et al.   SENSORS AND ACTUATORS B-CHEMICAL

Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics

(2016) Jaime A. Espinoza et al.   OncoImmunology

Wearable Chemical Sensors: Present Challenges and Future Prospects

(2016) Amay J. Bandodkar et al.   ACS Sensors

Integrated hollow microneedle-optofluidic biosensor for therapeutic drug monitoring in sub-nanoliter volumes

(2016) Sahan A. Ranamukhaarachchi et al.   Scientific Reports

Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

(2016) Maierdanjiang Wufuer et al.   Scientific Reports

Blood, sweat, and tears: developing clinically relevant protein biosensors for integrated body fluid analysis

(2015) S. R. Corrie et al.   ANALYST

PVDF-Nafion nanomembranes coated microneedles for in vivo transcutaneous implantable glucose sensing

(2015) Dajing Chen et al.   BIOSENSORS & BIOELECTRONICS

Self-powered microneedle-based biosensors for pain-free high-accuracy measurement of glycaemia in interstitial fluid

(2015) L.M. Strambini et al.   BIOSENSORS & BIOELECTRONICS

Nitrogen-incorporated ultrananocrystalline diamond microneedle arrays for electrochemical biosensing

(2015) Shelby A. Skoog et al.   DIAMOND AND RELATED MATERIALS

A needle-free technique for interstitial fluid sample acquisition using a lorentz-force actuated jet injector

(2015) Jean H. Chang et al.   JOURNAL OF CONTROLLED RELEASE

Microneedles for Transdermal Biosensing: Current Picture and Future Direction

(2015) Letizia Ventrelli et al.   Advanced Healthcare Materials

Development of Low Cost Rapid Fabrication of Sharp Polymer Microneedles for In Vivo Glucose Biosensing Applications

(2015) Colm Barrett et al.   ECS Journal of Solid State Science and Technology

Hydrogel-Forming Microneedle Arrays Allow Detection of Drugs and Glucose In Vivo: Potential for Use in Diagnosis and Therapeutic Drug Monitoring

(2015) Ester Caffarel-Salvador et al.   PLoS One

Collection of Analytes from Microneedle Patches

(2014) Andrey V. Romanyuk et al.   ANALYTICAL CHEMISTRY

Microneedle-based self-powered glucose sensor

(2014) Gabriela Valdés-Ramírez et al.   ELECTROCHEMISTRY COMMUNICATIONS

A proposed model membrane and test method for microneedle insertion studies

(2014) Eneko Larrañeta et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Hydrogel-Forming Microneedles Increase in Volume During Swelling in Skin, but Skin Barrier Function Recovery is Unaffected

(2014) Ryan F. Donnelly et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Microscopic gel–liquid interfaces supported by hollow microneedle array for voltammetric drug detection

(2014) Patricia Vazquez et al.   SENSORS AND ACTUATORS B-CHEMICAL

Interstitial fluid flow in cancer: implications for disease progression and treatment

(2014) Jennifer Munson et al.   Cancer Management and Research

Design, fabrication and characterization of drug delivery systems based on lab-on-a-chip technology

(2013) Nam-Trung Nguyen et al.   ADVANCED DRUG DELIVERY REVIEWS

Early circulating biomarker detection using a wearable microprojection array skin patch

(2013) Jacob W. Coffey et al.   BIOMATERIALS

Arrays of hollow out-of-plane microneedles made by metal electrodeposition onto solvent cast conductive polymer structures

(2013) I Mansoor et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Influence of Array Interspacing on the Force Required for Successful Microneedle Skin Penetration: Theoretical and Practical Approaches

(2013) Ololade Olatunji et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effect of Microneedle Geometry and Supporting Substrate on Microneedle Array Penetration into Skin

(2013) Jaspreet Singh Kochhar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Subcutaneous interstitial pressure and volume characteristics in renal impairment associated with edema

(2013) Leonard M. Ebah et al.   KIDNEY INTERNATIONAL

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

(2013) Jason D Ulrich et al.   Molecular Neurodegeneration

Numerical Modeling of Interstitial Fluid Flow Coupled with Blood Flow through a Remodeled Solid Tumor Microvascular Network

(2013) M. Soltani et al.   PLoS One

Interstitial Fluid Flow and Drug Delivery in Vascularized Tumors: A Computational Model

(2013) Michael Welter et al.   PLoS One

Age-dependent biomechanical properties of the skin

(2013) Mariola Pawlaczyk et al.   Postepy Dermatologii i Alergologii

Effect of microneedles shape on skin penetration and minimally invasive continuous glucose monitoring in vivo

(2013) Beelee Chua et al.   SENSORS AND ACTUATORS A-PHYSICAL

Microneedle-Based Transdermal Sensor for On-Chip Potentiometric Determination of K+

(2013) Philip R. Miller et al.   Advanced Healthcare Materials

The Importance of Mast Cells in Dermal Scarring

(2013) Traci A. Wilgus et al.   Advances in Wound Care

Cytotoxic Effects of Gold Nanoparticles: A Multiparametric Study

(2012) Stefaan J. Soenen et al.   ACS Nano

Interstitial fluid flow within bone canaliculi and electro-chemo-mechanical features of the canalicular milieu

(2012) Vittorio Sansalone et al.   Biomechanics and Modeling in Mechanobiology

A Minimally Invasive System for Glucose Area Under the Curve Measurement Using Interstitial Fluid Extraction Technology: Evaluation of the Accuracy and Usefulness with Oral Glucose Tolerance Tests in Subjects With and Without Diabetes

(2012) Kazuhiko Sakaguchi et al.   Diabetes Technology & Therapeutics

Interstitial Fluid Flow: The Mechanical Environment of Cells and Foundation of Meridians

(2012) Wei Yao et al.   Evidence-based Complementary and Alternative Medicine

An Interstitial Fluid Transdermal Extraction System for Continuous Glucose Monitoring

(2012) Haixia Yu et al.   JOURNAL OF MICROELECTROMECHANICAL SYSTEMS

Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer

(2012) Helge Wiig et al.   PHYSIOLOGICAL REVIEWS

High density and high aspect ratio solid micro-nanoprojection arrays for targeted skin vaccine delivery and specific antibody extraction

(2012) Derek Jenkins et al.   RSC Advances

Microneedle array-based carbon paste amperometric sensors and biosensors

(2011) Joshua Ray Windmiller et al.   ANALYST

Integrated carbon fiber electrodes within hollow polymer microneedles for transdermal electrochemical sensing

(2011) Philip R. Miller et al.   Biomicrofluidics

Microfluidic device to investigate factors affecting performance in biosensors designed for transdermal applications

(2011) Jakub Trzebinski et al.   LAB ON A CHIP

Multiplexed microneedle-based biosensor array for characterization of metabolic acidosis

(2011) Philip R. Miller et al.   TALANTA

Analysis of mechanical failure of polymer microneedles by axial force

(2010) Jung-Hwan Park et al.   JOURNAL OF THE KOREAN PHYSICAL SOCIETY

Characterization of the Liver Tissue Interstitial Fluid (TIF) Proteome Indicates Potential for Application in Liver Disease Biomarker Discovery

(2009) Wei Sun et al.   JOURNAL OF PROTEOME RESEARCH

Microneedle-based drug delivery: studies on delivery parameters and biocompatibility

(2008) Yan Wu et al.   BIOMEDICAL MICRODEVICES

Follicular transport route – Research progress and future perspectives

(2008) Fanny Knorr et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Role of Mast Cells in Acupuncture Effect: A Pilot Study

(2008) Di Zhang et al.   Explore-The Journal of Science and Healing

Optimizing microneedle arrays for transdermal drug delivery: Extension to non-square distribution of microneedles

(2008) Barrak Al-Qallaf et al.   JOURNAL OF DRUG TARGETING

Electrochemical Glucose Biosensors

(2007) Joseph Wang   CHEMICAL REVIEWS