Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives

Nitrogen Containing Heterocycles as Anticancer Agents: An Overview

(2020) Damanpreet K. Lang et al.   Anti-Cancer Agents in Medicinal Chemistry

Improving the odds of success in antitumoral drug development using scoring approaches towards heterocyclic scaffolds

(2020) George Ion et al.   ONCOLOGY REPORTS

The Effect of Resveratrol or Curcumin on Head and Neck Cancer Cells Sensitivity to the Cytotoxic Effects of Cisplatin

(2020) Marinela Bostan et al.   Nutrients

Novel 1,3,4-oxadiazole Targets STAT3 Signaling to Induce Antitumor Effect in Lung Cancer

(2020) Vikas H. Malojirao et al.   Biomedicines

Groundbreaking Anticancer Activity of Highly Diversified Oxadiazole Scaffolds

(2020) Alessandra Benassi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2

(2020) Rania Hamdy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies

(2020) Ana-Madalina Maciuca et al.   MOLECULES

A novel STAT3 inhibitor, STX-0119, attenuates liver fibrosis by inactivating hepatic stellate cells in mice

(2019) Seungho Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Methylation of tumour suppressor genes associated with thyroid cancer

(2019) Anca Botezatu et al.   Cancer Biomarkers

Discovery of natural naphthoquinones as sortase A inhibitors and potential anti‐infective solutions against Staphylococcus aureus

(2019) Georgiana Nitulescu et al.   DRUG DEVELOPMENT RESEARCH

The potential and controversy of targeting STAT family members in cancer

(2019) Yannick Verhoeven et al.   SEMINARS IN CANCER BIOLOGY

Cisplatin effect on head and neck squamous cell carcinoma cells is modulated by ERK1/2 protein kinases

(2019) Marinela Bostan et al.   Experimental and Therapeutic Medicine

1,3,4-Oxadiazoles as Telomerase Inhibitor: Potential Anticancer Agents

(2018) Shalini Bajaj et al.   Anti-Cancer Agents in Medicinal Chemistry

Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models

(2018) Oana Seremet et al.   Molecular Medicine Reports

Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole

(2018) Teresa Glomb et al.   MOLECULES

ChEMBL: towards direct deposition of bioassay data

(2018) David Mendez et al.   NUCLEIC ACIDS RESEARCH

Pharmacokinetic evaluation, molecular docking and in vitro biological evaluation of 1, 3, 4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors

(2018) Rashmin khanam et al.   Journal of Pharmaceutical Analysis

Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities

(2017) Jawaid Akhtar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, docking and QSAR study of substituted benzimidazole linked oxadiazole as cytotoxic agents, EGFR and erbB2 receptor inhibitors

(2017) Md Jawaid Akhtar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The control of DNA repair by the cell cycle

(2017) Nicole Hustedt et al.   NATURE CELL BIOLOGY

Combretastatin linked 1,3,4-oxadiazole conjugates as a Potent Tubulin Polymerization inhibitors

(2016) Ahmed Kamal et al.   BIOORGANIC CHEMISTRY

MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression

(2016) Chenli Li et al.   BMC CANCER

Synthesis and in vitro antiproliferative activity of new 1,3,4-oxadiazole derivatives possessing sulfonamide moiety

(2015) Mahmoud M. Gamal El-Din et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1,3,4-Oxadiazoles: An emerging scaffold to target growth factors, enzymes and kinases as anticancer agents

(2015) Shalini Bajaj et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis

(2015) Thomas Sander et al.   Journal of Chemical Information and Modeling

Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53 mediated intrinsic pathway

(2015) Neena M. Sankhe et al.   Arabian Journal of Chemistry

Prediction of the Biological Activity Spectra of Organic Compounds Using the Pass Online Web Resource

(2014) D. A. Filimonov et al.   Chemistry of Heterocyclic Compounds

A New Approach to Radial Basis Function Approximation and Its Application to QSAR

(2014) Alexey V. Zakharov et al.   Journal of Chemical Information and Modeling

1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

(2014) Sergio Valente et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, biological evaluation, and molecular docking studies of novel 1,3,4-oxadiazole derivatives possessing benzotriazole moiety as FAK inhibitors with anticancer activity

(2013) Shuai Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel 1,3,4-oxadiazole thioether derivatives targeting thymidylate synthase as dual anticancer/antimicrobial agents

(2013) Qian-Ru Du et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and antitumor activity of 1,3,4-oxadiazole possessing 1,4-benzodioxan moiety as a novel class of potent methionine aminopeptidase type II inhibitors

(2013) Juan Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel Dibenzothiepins with Antibiofilm Activity Demonstrated by Microbiological Assays and Molecular Modeling

(2013) Camelia Stecoza et al.   CURRENT ORGANIC CHEMISTRY

Fragment-based drug design and identification of HJC0123 , a novel orally bioavailable STAT3 inhibitor for cancer therapy

(2013) Haijun Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2,5-Disubstituted-1,3,4-oxadiazoles: thymidine phosphorylase inhibitors

(2013) Khalid Mohammed Khan et al.   MEDICINAL CHEMISTRY RESEARCH

DNA binding and antiproliferative activity toward human carcinoma cells of copper(ii) and zinc(ii) complexes of a 2,5-diphenyl[1,3,4]oxadiazole derivative

(2012) Alessio Terenzi et al.   DALTON TRANSACTIONS

Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents

(2011) Xiao-Min Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: Design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors

(2011) Harish Rajak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, molecular modeling and biological evaluation of 2-(benzylthio)-5-aryloxadiazole derivatives as anti-tumor agents

(2011) Kai Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Oxadiazoles in Medicinal Chemistry

(2011) Jonas Boström et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of a New Series of STAT3 Inhibitors by Virtual Screening

(2010) Kenji Matsuno et al.   ACS Medicinal Chemistry Letters

Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor

(2008) Réjean Ruel et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: Synthesis and preliminary evaluation of biological properties

(2008) Harish Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY