Changes of Lipopolysaccharide-Induced Acute Kidney and Liver Injuries in Rats Based on Metabolomics Analysis

PCTR1 ameliorates lipopolysaccharide-induced acute inflammation and multiple organ damage via regulation of linoleic acid metabolism by promoting FADS1/FASDS2/ELOV2 expression and reducing PLA2 expression

(2020) Yong-jian Liu et al.   LABORATORY INVESTIGATION

Identification of key metabolites during cisplatin-induced acute kidney injury using an HPLC-TOF/MS-based non-targeted urine and kidney metabolomics approach in rats

(2020) Xiaoyu Qu et al.   TOXICOLOGY

Integration of GC-MS and LC-MS For Untargeted Metabolomics Profiling

(2020) Özge Cansın Zeki et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Comprehensive Evaluation of Lipopolysaccharide-Induced Changes in Rats Based on Metabolomics

(2020) Chunmei Geng et al.   Journal of Inflammation Research

A Cell-Based Metabonomics Approach to Investigate the Varied Influences of Chrysophanol-8-O-β-D-Glucoside With Different Concentrations on L-02 Cells

(2019) Meichen Liu et al.   Frontiers in Pharmacology

The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance

(2019) Xing Huang et al.   Autophagy

Glutamine Therapy Reduces Inflammation and Extracellular Trap Release in Experimental Acute Respiratory Distress Syndrome of Pulmonary Origin

(2019) Gisele Pena de Oliveira et al.   Nutrients

Dexmedetomidine ameliorates LPS induced acute lung injury via GSK-3β/STAT3-NF-κB signaling pathway in rats

(2019) Huayun Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metabolic profiling of liver tissues in mice after instillation of fine particulate matter

(2019) Chunzhen Shi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Enhancing the activity and stability of Mn-superoxide dismutase by one-by-one ligation to catalase

(2018) Rong Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipid profile perturbations in the plasma and lungs of mice with LPS-induced acute lung injury revealed by UHPLC-ESI-Q Exactive HF MS analysis

(2018) Jinjun Shan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Response to different dietary carbohydrate and protein levels of pearl oysters (Pinctada fucata martensii) as revealed by GC–TOF/MS-based metabolomics

(2018) Chuangye Yang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Taurine alleviates lipopolysaccharide-induced liver injury by anti-inflammation and antioxidants in rats

(2017) Yueyan Liu et al.   Molecular Medicine Reports

Metabolomics as a Driver in Advancing Precision Medicine in Sepsis

(2017) Michelle Eckerle et al.   PHARMACOTHERAPY

A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus

(2017) Ying Zhu et al.   mBio

Glutamine inhibits CCl4 induced liver fibrosis in mice and TGF-β1 mediated epithelial–mesenchymal transition in mouse hepatocytes

(2016) Nirajan Shrestha et al.   FOOD AND CHEMICAL TOXICOLOGY

Apocynin ameliorates endotoxin-induced acute lung injury in rats

(2016) Marwa E. Abdelmageed et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Untargeted Metabolomics Strategies—Challenges and Emerging Directions

(2016) Alexandra C. Schrimpe-Rutledge et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism

(2016) Ameer Y. Taha et al.   MOLECULAR NEUROBIOLOGY

Protection of baicalin against lipopolysaccharide induced liver and kidney injuries based on 1H NMR metabolomic profiling

(2016) Shanting Liao et al.   Toxicology Research

Moderate Exercise Attenuates Lipopolysaccharide-Induced Inflammation and Associated Maternal and Fetal Morbidities in Pregnant Rats

(2016) Karina T. Kasawara et al.   PLoS One

Malondialdehyde; Lipid peroxidation plasma biomarker correlated with hepatic fibrosis in human Schistosoma mansoni infection

(2015) Inas Abdel Aziz et al.   ACTA PARASITOLOGICA

Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse

(2015) Seán T. Anderson et al.   BRAIN BEHAVIOR AND IMMUNITY

Application of Glutathione as Anti-Oxidative and Anti-Aging Drugs

(2015) Takujiro Homma et al.   CURRENT DRUG METABOLISM

Analysis of the Human Adult Urinary Metabolome Variations with Age, Body Mass Index, and Gender by Implementing a Comprehensive Workflow for Univariate and OPLS Statistical Analyses

(2015) Etienne A. Thévenot et al.   JOURNAL OF PROTEOME RESEARCH

Metabolomic analysis of arginine metabolism in acute hepatic injury in rats

(2014) Wataru Saitoh et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Potential Role of Uric Acid in Metabolic Syndrome, Hypertension, Kidney Injury, and Cardiovascular Diseases: Is It Time for Reappraisal?

(2013) Zohreh Soltani et al.   CURRENT HYPERTENSION REPORTS

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type-Specific Functions of TLR4 during Sepsis

(2013) M. Deng et al.   JOURNAL OF IMMUNOLOGY

Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

(2013) Gordon F. Rushworth et al.   PHARMACOLOGY & THERAPEUTICS

Primary antioxidant free radical scavenging and redox signaling pathways in higher plant cells

(2012) Hong-Bo Shao et al.   International Journal of Biological Sciences

Global metabolic profiling of animal and human tissues via UPLC-MS

(2012) Elizabeth J Want et al.   Nature Protocols

Experimental Human Endotoxemia: A Model of the Systemic Inflammatory Response Syndrome?

(2012) Steve E. Calvano et al.   Surgical Infections

Long-term Ambient Fine Particulate Matter Air Pollution and Lung Cancer in a Large Cohort of Never-Smokers

(2011) Michelle C. Turner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

(2011) Warwick B Dunn et al.   Nature Protocols

Development of a Robust and Repeatable UPLC−MS Method for the Long-Term Metabolomic Study of Human Serum

(2009) Eva Zelena et al.   ANALYTICAL CHEMISTRY

Glutamine attenuates lipopolysaccharide-induced acute lung injury

(2009) Feng Zhang et al.   NUTRITION